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Protein

54S ribosomal protein L23, mitochondrial

Gene

MRPL23

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • mRNA binding Source: GO_Central
  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • mitochondrial translation Source: SGD
  • translation Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-33667-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
54S ribosomal protein L23, mitochondrial
Alternative name(s):
YmL23
Gene namesi
Name:MRPL23
Ordered Locus Names:YOR150W
ORF Names:O3530
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOR150W.
SGDiS000005676. MRPL23.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial large ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
PropeptideiPRO_00000304622 – 41 Publication3
ChainiPRO_00000304635 – 16354S ribosomal protein L23, mitochondrialAdd BLAST159

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiQ12487.
PRIDEiQ12487.

Interactioni

Subunit structurei

Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).2 Publications

Protein-protein interaction databases

BioGridi34546. 14 interactors.
DIPiDIP-5385N.
IntActiQ12487. 7 interactors.
MINTiMINT-502479.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J6Belectron microscopy3.20H1-163[»]
ProteinModelPortaliQ12487.
SMRiQ12487.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L13P family.Curated

Phylogenomic databases

GeneTreeiENSGT00390000001515.
HOGENOMiHOG000225288.
InParanoidiQ12487.
KOiK02871.
OMAiAYARVWH.
OrthoDBiEOG092C59OH.

Family and domain databases

CDDicd00392. Ribosomal_L13. 1 hit.
Gene3Di3.90.1180.10. 1 hit.
HAMAPiMF_01366. Ribosomal_L13. 1 hit.
InterProiIPR005822. Ribosomal_L13.
IPR005823. Ribosomal_L13_bac-type.
IPR023563. Ribosomal_L13_CS.
[Graphical view]
PANTHERiPTHR11545. PTHR11545. 1 hit.
PfamiPF00572. Ribosomal_L13. 1 hit.
[Graphical view]
PIRSFiPIRSF002181. Ribosomal_L13. 1 hit.
SUPFAMiSSF52161. SSF52161. 1 hit.
TIGRFAMsiTIGR01066. rplM_bact. 1 hit.
PROSITEiPS00783. RIBOSOMAL_L13. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q12487-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQKIGHSGL AFARLWHHVD VARDKRTLGR LASAIAITLI GRHKPVYHPS
60 70 80 90 100
QDCGDYVVVT NCQKIRVTGK KFEQKTYWSH SGRPGQLKLQ TMNKVVADKG
110 120 130 140 150
FGEILKKAVS GMLPKNKLRK QRLDRLKVFD GSENPYKQNI TAFAHEQSSI
160
PEPLKESIFN QLK
Length:163
Mass (Da):18,463
Last modified:November 1, 1996 - v1
Checksum:i5FD27E5A965F6315
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti5I → K AA sequence (PubMed:9151978).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U55020 Genomic DNA. Translation: AAC49636.1.
Z75058 Genomic DNA. Translation: CAA99356.1.
AY558133 Genomic DNA. Translation: AAS56459.1.
BK006948 Genomic DNA. Translation: DAA10923.1.
PIRiS67038.
RefSeqiNP_014793.1. NM_001183569.1.

Genome annotation databases

EnsemblFungiiYOR150W; YOR150W; YOR150W.
GeneIDi854321.
KEGGisce:YOR150W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U55020 Genomic DNA. Translation: AAC49636.1.
Z75058 Genomic DNA. Translation: CAA99356.1.
AY558133 Genomic DNA. Translation: AAS56459.1.
BK006948 Genomic DNA. Translation: DAA10923.1.
PIRiS67038.
RefSeqiNP_014793.1. NM_001183569.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J6Belectron microscopy3.20H1-163[»]
ProteinModelPortaliQ12487.
SMRiQ12487.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34546. 14 interactors.
DIPiDIP-5385N.
IntActiQ12487. 7 interactors.
MINTiMINT-502479.

Proteomic databases

MaxQBiQ12487.
PRIDEiQ12487.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYOR150W; YOR150W; YOR150W.
GeneIDi854321.
KEGGisce:YOR150W.

Organism-specific databases

EuPathDBiFungiDB:YOR150W.
SGDiS000005676. MRPL23.

Phylogenomic databases

GeneTreeiENSGT00390000001515.
HOGENOMiHOG000225288.
InParanoidiQ12487.
KOiK02871.
OMAiAYARVWH.
OrthoDBiEOG092C59OH.

Enzyme and pathway databases

BioCyciYEAST:G3O-33667-MONOMER.

Miscellaneous databases

PROiQ12487.

Family and domain databases

CDDicd00392. Ribosomal_L13. 1 hit.
Gene3Di3.90.1180.10. 1 hit.
HAMAPiMF_01366. Ribosomal_L13. 1 hit.
InterProiIPR005822. Ribosomal_L13.
IPR005823. Ribosomal_L13_bac-type.
IPR023563. Ribosomal_L13_CS.
[Graphical view]
PANTHERiPTHR11545. PTHR11545. 1 hit.
PfamiPF00572. Ribosomal_L13. 1 hit.
[Graphical view]
PIRSFiPIRSF002181. Ribosomal_L13. 1 hit.
SUPFAMiSSF52161. SSF52161. 1 hit.
TIGRFAMsiTIGR01066. rplM_bact. 1 hit.
PROSITEiPS00783. RIBOSOMAL_L13. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRM23_YEAST
AccessioniPrimary (citable) accession number: Q12487
Secondary accession number(s): D6W2K7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 141 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 6700 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.