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Protein

PHO85 cyclin-9

Gene

PCL9

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

M/G1-specific cyclin partner of the cyclin-dependent kinase (CDK) PHO85. May have a role in bud site selection in G1 phase.2 Publications

GO - Molecular functioni

  • cyclin-dependent protein serine/threonine kinase regulator activity Source: SGD
  • protein kinase binding Source: InterPro

GO - Biological processi

Keywordsi

Molecular functionCyclin
Biological processCell cycle, Cell division

Enzyme and pathway databases

BioCyciYEAST:G3O-29566-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
PHO85 cyclin-9
Gene namesi
Name:PCL9
Ordered Locus Names:YDL179W
ORF Names:D1408
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDL179W.
SGDiS000002338. PCL9.

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002717881 – 304PHO85 cyclin-9Add BLAST304

Proteomic databases

PRIDEiQ12477.

Expressioni

Inductioni

By transcription factor SWI5 in a cell cycle-regulated manner. Peaks in late M, early G1 phase (at protein level).2 Publications

Interactioni

Subunit structurei

Forms a cyclin-CDK complex with PHO85.

Binary interactionsi

WithEntry#Exp.IntActNotes
PHO85P171574EBI-38090,EBI-13327

GO - Molecular functioni

Protein-protein interaction databases

BioGridi31887. 58 interactors.
DIPiDIP-1510N.
IntActiQ12477. 12 interactors.
MINTiMINT-408364.
STRINGi4932.YDL179W.

Structurei

3D structure databases

ProteinModelPortaliQ12477.
SMRiQ12477.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 146Cyclin N-terminalAdd BLAST128

Sequence similaritiesi

Belongs to the cyclin family. PCL1,2 subfamily.Curated

Phylogenomic databases

GeneTreeiENSGT00390000004809.
HOGENOMiHOG000000866.
InParanoidiQ12477.
OrthoDBiEOG092C3KSL.

Family and domain databases

CDDicd00043. CYCLIN. 1 hit.
Gene3Di1.10.472.10. 2 hits.
InterProiView protein in InterPro
IPR013763. Cyclin-like.
IPR006671. Cyclin_N.
IPR012104. PHO85_cyclin_1/2/9.
PfamiView protein in Pfam
PF00134. Cyclin_N. 1 hit.
PIRSFiPIRSF016511. Cyclin_Pcl. 1 hit.
SMARTiView protein in SMART
SM00385. CYCLIN. 1 hit.
SUPFAMiSSF47954. SSF47954. 1 hit.

Sequencei

Sequence statusi: Complete.

Q12477-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISDYDALLQ FNKKPVSQEM IQFLATSTAS IIKIRENNNP IQGCRPPDLS
60 70 80 90 100
IFIKNVVIQS NVQTPTLMAT SVYLNKLKSV IPKNVYGINT TRHRIFLGCL
110 120 130 140 150
ILAAKTLNDS SPWNKHWTTY TEGLLRIREV NTIERELLEY LNWDVRITTP
160 170 180 190 200
DLIDSLSYFL GPIKEQLFLQ RRQEMLLFNA PSPGQLKEYI NHRRPVSHSR
210 220 230 240 250
TSSAISVPSL TSMATVSTTD SRSSLLAKYQ PSLPLVESDN FNKKNHVPLR
260 270 280 290 300
NNNDICNNFR AEENIHSVNH IDVTMGSSPV MSHKPTIHQR LNFTRRGWSS

FFKQ
Length:304
Mass (Da):34,798
Last modified:November 1, 1996 - v1
Checksum:i183820067EC00D23
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z67750 Genomic DNA. Translation: CAA91566.1.
Z74227 Genomic DNA. Translation: CAA98753.1.
AY557655 Genomic DNA. Translation: AAS55981.1.
BK006938 Genomic DNA. Translation: DAA11683.1.
PIRiS61033.
RefSeqiNP_010102.1. NM_001180239.1.

Genome annotation databases

EnsemblFungiiYDL179W; YDL179W; YDL179W.
GeneIDi851375.
KEGGisce:YDL179W.

Similar proteinsi

Entry informationi

Entry nameiPCL9_YEAST
AccessioniPrimary (citable) accession number: Q12477
Secondary accession number(s): D6VRH3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: November 1, 1996
Last modified: September 27, 2017
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names