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Protein

MIOREX complex component 4

Gene

MRX4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression.1 Publication

Enzyme and pathway databases

BioCyciYEAST:G3O-34064-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
MIOREX complex component 41 Publication
Alternative name(s):
Mitochondrial organization of gene expression protein 41 Publication
Gene namesi
Name:MRX41 Publication
Ordered Locus Names:YPL168WImported
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPL168W.
SGDiS000006089. MRX4.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei403 – 42018HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 2727MitochondrionSequence analysisAdd
BLAST
Chaini28 – 430403MIOREX complex component 4PRO_0000238656Add
BLAST

Proteomic databases

MaxQBiQ12467.
PRIDEiQ12467.

Expressioni

Inductioni

During M phase of cell cycle.1 Publication

Interactioni

Subunit structurei

Associates with the mitochondrial ribosome.1 Publication

Protein-protein interaction databases

BioGridi36015. 14 interactions.
IntActiQ12467. 1 interaction.
MINTiMINT-4505189.

Structurei

3D structure databases

ProteinModelPortaliQ12467.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ12467.
OMAiTIANNAW.
OrthoDBiEOG092C5P6Q.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q12467-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVLYTSASL KKMKCLAFNM GMNCVRTVSH ARSGGAKFGG RNVFNIFDSK
60 70 80 90 100
TPDSVRIKAF KNTIYQSAMG KGKTKFSAME INLITSLVRG YKGEGKKNAI
110 120 130 140 150
NPLQTNVQIL NKLLLTHRLT DKDILEGMNL AAGPVNVAIP RDITPQEEKK
160 170 180 190 200
KVELRNRKAE NMDLHPSRKM HIKELLHSLN LDMCNDEEVY QKISLYLQKN
210 220 230 240 250
EESRTSVGAS QQNHVDIDIN SLKRYLQNIE KKARQKSAID KQKKNQARIY
260 270 280 290 300
QWNTQSFSEI VPLSAGNILF KREPNRLWKR LQNGISVFLG SNGGGKKSKT
310 320 330 340 350
TKKVLQGNNI LLHSLENNKD MTLSNNFDHS VFNINFTDLF GVINASGSPP
360 370 380 390 400
DRVLNEINEI ELKGWKCVGN LYDNNKIVVF QSSNPLLEDT KIPQKSFTNS
410 420 430
KRFLISLSAL LASFFAYYRY RLSQRQESKK
Length:430
Mass (Da):48,827
Last modified:November 1, 1996 - v1
Checksum:i235ACBBC212D0541
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X96770 Genomic DNA. Translation: CAA65553.1.
Z73524 Genomic DNA. Translation: CAA97874.1.
BK006949 Genomic DNA. Translation: DAA11266.1.
PIRiS65179.
RefSeqiNP_015157.1. NM_001183982.1.

Genome annotation databases

EnsemblFungiiYPL168W; YPL168W; YPL168W.
GeneIDi855935.
KEGGisce:YPL168W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X96770 Genomic DNA. Translation: CAA65553.1.
Z73524 Genomic DNA. Translation: CAA97874.1.
BK006949 Genomic DNA. Translation: DAA11266.1.
PIRiS65179.
RefSeqiNP_015157.1. NM_001183982.1.

3D structure databases

ProteinModelPortaliQ12467.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36015. 14 interactions.
IntActiQ12467. 1 interaction.
MINTiMINT-4505189.

Proteomic databases

MaxQBiQ12467.
PRIDEiQ12467.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYPL168W; YPL168W; YPL168W.
GeneIDi855935.
KEGGisce:YPL168W.

Organism-specific databases

EuPathDBiFungiDB:YPL168W.
SGDiS000006089. MRX4.

Phylogenomic databases

InParanoidiQ12467.
OMAiTIANNAW.
OrthoDBiEOG092C5P6Q.

Enzyme and pathway databases

BioCyciYEAST:G3O-34064-MONOMER.

Miscellaneous databases

PROiQ12467.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiMRX4_YEAST
AccessioniPrimary (citable) accession number: Q12467
Secondary accession number(s): D6W3K0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.