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Protein

MIOREX complex component 4

Gene

MRX4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression.1 Publication

Enzyme and pathway databases

BioCyciYEAST:G3O-34064-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
MIOREX complex component 41 Publication
Alternative name(s):
Mitochondrial organization of gene expression protein 41 Publication
Gene namesi
Name:MRX41 Publication
Ordered Locus Names:YPL168WImported
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPL168W
SGDiS000006089 MRX4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei403 – 420HelicalSequence analysisAdd BLAST18

Keywords - Cellular componenti

Membrane, Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 27MitochondrionSequence analysisAdd BLAST27
ChainiPRO_000023865628 – 430MIOREX complex component 4Add BLAST403

Proteomic databases

MaxQBiQ12467
PaxDbiQ12467
PRIDEiQ12467

Expressioni

Inductioni

During M phase of cell cycle.1 Publication

Interactioni

Subunit structurei

Associates with the mitochondrial ribosome.1 Publication

Protein-protein interaction databases

BioGridi36015, 90 interactors
IntActiQ12467, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliQ12467
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ12467
OMAiTIANNAW
OrthoDBiEOG092C5P6Q

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q12467-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVLYTSASL KKMKCLAFNM GMNCVRTVSH ARSGGAKFGG RNVFNIFDSK
60 70 80 90 100
TPDSVRIKAF KNTIYQSAMG KGKTKFSAME INLITSLVRG YKGEGKKNAI
110 120 130 140 150
NPLQTNVQIL NKLLLTHRLT DKDILEGMNL AAGPVNVAIP RDITPQEEKK
160 170 180 190 200
KVELRNRKAE NMDLHPSRKM HIKELLHSLN LDMCNDEEVY QKISLYLQKN
210 220 230 240 250
EESRTSVGAS QQNHVDIDIN SLKRYLQNIE KKARQKSAID KQKKNQARIY
260 270 280 290 300
QWNTQSFSEI VPLSAGNILF KREPNRLWKR LQNGISVFLG SNGGGKKSKT
310 320 330 340 350
TKKVLQGNNI LLHSLENNKD MTLSNNFDHS VFNINFTDLF GVINASGSPP
360 370 380 390 400
DRVLNEINEI ELKGWKCVGN LYDNNKIVVF QSSNPLLEDT KIPQKSFTNS
410 420 430
KRFLISLSAL LASFFAYYRY RLSQRQESKK
Length:430
Mass (Da):48,827
Last modified:November 1, 1996 - v1
Checksum:i235ACBBC212D0541
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X96770 Genomic DNA Translation: CAA65553.1
Z73524 Genomic DNA Translation: CAA97874.1
BK006949 Genomic DNA Translation: DAA11266.1
PIRiS65179
RefSeqiNP_015157.1, NM_001183982.1

Genome annotation databases

EnsemblFungiiYPL168W; YPL168W; YPL168W
GeneIDi855935
KEGGisce:YPL168W

Similar proteinsi

Entry informationi

Entry nameiMRX4_YEAST
AccessioniPrimary (citable) accession number: Q12467
Secondary accession number(s): D6W3K0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names

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