Q12467 (YP168_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YPL168W

Gene names

Ordered Locus Names:

YPL168W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	430 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Mitochondrion membrane; Single-pass membrane protein Potential Ref.4.
Induction	During M phase of cell cycle. Ref.5

Ontologies

Keywords
Cellular component	Membrane Mitochondrion
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW mitochondrial membrane Inferred from electronic annotation. Source: UniProtKB-SubCell mitochondrion Inferred from direct assay Ref.4. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 430	430	Uncharacterized protein YPL168W		PRO_0000238656
Regions
	Transmembrane	403 – 420	18	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q12467 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 235ACBBC212D0541	FASTA	430	48,827
	10 20 30 40 50 60 MTVLYTSASL KKMKCLAFNM GMNCVRTVSH ARSGGAKFGG RNVFNIFDSK TPDSVRIKAF 70 80 90 100 110 120 KNTIYQSAMG KGKTKFSAME INLITSLVRG YKGEGKKNAI NPLQTNVQIL NKLLLTHRLT 130 140 150 160 170 180 DKDILEGMNL AAGPVNVAIP RDITPQEEKK KVELRNRKAE NMDLHPSRKM HIKELLHSLN 190 200 210 220 230 240 LDMCNDEEVY QKISLYLQKN EESRTSVGAS QQNHVDIDIN SLKRYLQNIE KKARQKSAID 250 260 270 280 290 300 KQKKNQARIY QWNTQSFSEI VPLSAGNILF KREPNRLWKR LQNGISVFLG SNGGGKKSKT 310 320 330 340 350 360 TKKVLQGNNI LLHSLENNKD MTLSNNFDHS VFNINFTDLF GVINASGSPP DRVLNEINEI 370 380 390 400 410 420 ELKGWKCVGN LYDNNKIVVF QSSNPLLEDT KIPQKSFTNS KRFLISLSAL LASFFAYYRY 430 RLSQRQESKK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The sequence of 55 kb on the left arm of yeast chromosome XVI identifies a small nuclear RNA, a new putative protein kinase and two new putative regulators." Purnelle B., Coster F., Goffeau A. Yeast 12:1483-1492(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI." Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M. , Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J. Nature 387:103-105(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[3]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[4]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]	"New weakly expressed cell cycle-regulated genes in yeast." de Lichtenberg U., Wernersson R., Jensen T.S., Nielsen H.B., Fausboell A., Schmidt P., Hansen F.B., Knudsen S., Brunak S. Yeast 22:1191-1201(2005) [PubMed] [Europe PMC] [Abstract] Cited for: INDUCTION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X96770 Genomic DNA. Translation: CAA65553.1. Z73524 Genomic DNA. Translation: CAA97874.1. BK006949 Genomic DNA. Translation: DAA11266.1.
PIR	S65179.
RefSeq	NP_015157.1. NM_001183982.1.
3D structure databases
ProteinModelPortal	Q12467.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q12467. 1 interaction.
STRING	4932.YPL168W.
Proteomic databases
PaxDb	Q12467.
PRIDE	Q12467.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YPL168W; YPL168W; YPL168W.
GeneID	855935.
KEGG	sce:YPL168W.
Organism-specific databases
CYGD	YPL168w.
SGD	S000006089. YPL168W.
Phylogenomic databases
eggNOG	NOG68856.
OMA	HTIANNA.
OrthoDB	EOG40GH1N.
Gene expression databases
Genevestigator	Q12467.
GermOnline	YPL168W. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other
NextBio	980684.

Entry information

Entry name

YP168_YEAST

Accession

Primary (citable) accession number: Q12467
Secondary accession number(s): D6W3K0

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2006
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program