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Protein

Peroxisomal membrane protein PMP27

Gene

PEX11

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in peroxisomal proliferation. Promotes peroxisome division and biogenesis.3 Publications

Miscellaneous

Present with 1630 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • fatty acid oxidation Source: SGD
  • peroxisome fission Source: UniProtKB
  • peroxisome organization Source: UniProtKB
  • regulation of peroxisome size Source: UniProtKB
  • signal transduction Source: UniProtKB

Keywordsi

Biological processPeroxisome biogenesis

Enzyme and pathway databases

BioCyciYEAST:G3O-33537-MONOMER

Protein family/group databases

TCDBi1.A.101.1.1 the peroxisomal pore-forming pex11 (pex11) family
3.A.20.1.5 the peroxisomal protein importer (ppi) family

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxisomal membrane protein PMP27
Alternative name(s):
Peroxin-11
Gene namesi
Name:PEX11
Synonyms:PMP24, PMP27
Ordered Locus Names:YOL147C
ORF Names:O0454
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOL147C
SGDiS000005507 PEX11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved2 Publications
ChainiPRO_00001059742 – 236Peroxisomal membrane protein PMP27Add BLAST235

Proteomic databases

MaxQBiQ12462
PaxDbiQ12462
PRIDEiQ12462

Interactioni

Subunit structurei

Homooligomer. Interacts with PEX34.3 Publications

Protein-protein interaction databases

BioGridi34270, 73 interactors
DIPiDIP-3839N
IntActiQ12462, 34 interactors
MINTiQ12462
STRINGi4932.YOL147C

Structurei

3D structure databases

ProteinModelPortaliQ12462
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peroxin-11 family.Curated

Phylogenomic databases

HOGENOMiHOG000214966
InParanoidiQ12462
OMAiCDFFIPL
OrthoDBiEOG092C46ES

Family and domain databases

InterProiView protein in InterPro
IPR008733 PEX11
PfamiView protein in Pfam
PF05648 PEX11, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q12462-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVCDTLVYHP SVTRFVKFLD GSAGREKVLR LLQYLARFLA VQNSSLLARQ
60 70 80 90 100
LQAQFTTVRK FLRFLKPLNH LQAAAKFYDN KLASDNVVRV CNVLKNIFFA
110 120 130 140 150
AYLSLDQVNL LRILKVIPVT VLTGKKIPRW SNWCWLFGLL SGLAMDLRKI
160 170 180 190 200
QTSHAQIAAF VKAKSQSQGD EHEDHKKVLG KAYQDRYTAL RRLFWDAADS
210 220 230
FIVLNNLGYL SSNEEYVALS GVVTSILGMQ DMWKAT
Length:236
Mass (Da):26,875
Last modified:January 23, 2007 - v2
Checksum:i26B95896D57018DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48239 Genomic DNA Translation: CAA88280.1
Z74889 Genomic DNA Translation: CAA99168.1
X81465 Genomic DNA Translation: CAA57223.1
Z46846 Genomic DNA Translation: CAA86903.1
AY558010 Genomic DNA Translation: AAS56336.1
BK006948 Genomic DNA Translation: DAA10638.1
PIRiA56509
RefSeqiNP_014494.1, NM_001183401.1

Genome annotation databases

EnsemblFungiiYOL147C; YOL147C; YOL147C
GeneIDi854018
KEGGisce:YOL147C

Similar proteinsi

Entry informationi

Entry nameiPEX11_YEAST
AccessioniPrimary (citable) accession number: Q12462
Secondary accession number(s): D6W1S2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: January 23, 2007
Last modified: April 25, 2018
This is version 138 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome
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Main funding by: National Institutes of Health