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Protein

Peroxisomal membrane protein PMP27

Gene

PEX11

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Involved in peroxisomal proliferation. Promotes peroxisome division and biogenesis.3 Publications

GO - Biological processi

  • fatty acid oxidation Source: SGD
  • peroxisome fission Source: UniProtKB
  • peroxisome organization Source: UniProtKB
  • regulation of peroxisome size Source: UniProtKB
  • signal transduction Source: UniProtKB
Complete GO annotation...

Keywords - Biological processi

Peroxisome biogenesis

Enzyme and pathway databases

BioCyciYEAST:G3O-33537-MONOMER.

Protein family/group databases

TCDBi1.A.101.1.1. the peroxisomal pore-forming pex11 (pex11) family.
3.A.20.1.5. the peroxisomal protein importer (ppi) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxisomal membrane protein PMP27
Alternative name(s):
Peroxin-11
Gene namesi
Name:PEX11
Synonyms:PMP24, PMP27
Ordered Locus Names:YOL147C
ORF Names:O0454
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOL147C.
SGDiS000005507. PEX11.

Subcellular locationi

GO - Cellular componenti

  • endoplasmic reticulum Source: SGD
  • integral component of peroxisomal membrane Source: UniProtKB
  • peroxisomal importomer complex Source: SGD
  • peroxisomal membrane Source: SGD
  • peroxisome Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved2 Publications
ChainiPRO_00001059742 – 236Peroxisomal membrane protein PMP27Add BLAST235

Proteomic databases

MaxQBiQ12462.
PRIDEiQ12462.

Interactioni

Subunit structurei

Homooligomer. Interacts with PEX34.3 Publications

Protein-protein interaction databases

BioGridi34270. 44 interactors.
DIPiDIP-3839N.
IntActiQ12462. 28 interactors.
MINTiMINT-500737.

Structurei

3D structure databases

ProteinModelPortaliQ12462.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peroxin-11 family.Curated

Phylogenomic databases

HOGENOMiHOG000214966.
InParanoidiQ12462.
OMAiYLHFTEG.
OrthoDBiEOG092C46ES.

Family and domain databases

InterProiIPR008733. PEX11.
[Graphical view]
PfamiPF05648. PEX11. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q12462-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVCDTLVYHP SVTRFVKFLD GSAGREKVLR LLQYLARFLA VQNSSLLARQ
60 70 80 90 100
LQAQFTTVRK FLRFLKPLNH LQAAAKFYDN KLASDNVVRV CNVLKNIFFA
110 120 130 140 150
AYLSLDQVNL LRILKVIPVT VLTGKKIPRW SNWCWLFGLL SGLAMDLRKI
160 170 180 190 200
QTSHAQIAAF VKAKSQSQGD EHEDHKKVLG KAYQDRYTAL RRLFWDAADS
210 220 230
FIVLNNLGYL SSNEEYVALS GVVTSILGMQ DMWKAT
Length:236
Mass (Da):26,875
Last modified:January 23, 2007 - v2
Checksum:i26B95896D57018DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48239 Genomic DNA. Translation: CAA88280.1.
Z74889 Genomic DNA. Translation: CAA99168.1.
X81465 Genomic DNA. Translation: CAA57223.1.
Z46846 Genomic DNA. Translation: CAA86903.1.
AY558010 Genomic DNA. Translation: AAS56336.1.
BK006948 Genomic DNA. Translation: DAA10638.1.
PIRiA56509.
RefSeqiNP_014494.1. NM_001183401.1.

Genome annotation databases

EnsemblFungiiYOL147C; YOL147C; YOL147C.
GeneIDi854018.
KEGGisce:YOL147C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48239 Genomic DNA. Translation: CAA88280.1.
Z74889 Genomic DNA. Translation: CAA99168.1.
X81465 Genomic DNA. Translation: CAA57223.1.
Z46846 Genomic DNA. Translation: CAA86903.1.
AY558010 Genomic DNA. Translation: AAS56336.1.
BK006948 Genomic DNA. Translation: DAA10638.1.
PIRiA56509.
RefSeqiNP_014494.1. NM_001183401.1.

3D structure databases

ProteinModelPortaliQ12462.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34270. 44 interactors.
DIPiDIP-3839N.
IntActiQ12462. 28 interactors.
MINTiMINT-500737.

Protein family/group databases

TCDBi1.A.101.1.1. the peroxisomal pore-forming pex11 (pex11) family.
3.A.20.1.5. the peroxisomal protein importer (ppi) family.

Proteomic databases

MaxQBiQ12462.
PRIDEiQ12462.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYOL147C; YOL147C; YOL147C.
GeneIDi854018.
KEGGisce:YOL147C.

Organism-specific databases

EuPathDBiFungiDB:YOL147C.
SGDiS000005507. PEX11.

Phylogenomic databases

HOGENOMiHOG000214966.
InParanoidiQ12462.
OMAiYLHFTEG.
OrthoDBiEOG092C46ES.

Enzyme and pathway databases

BioCyciYEAST:G3O-33537-MONOMER.

Miscellaneous databases

PROiQ12462.

Family and domain databases

InterProiIPR008733. PEX11.
[Graphical view]
PfamiPF05648. PEX11. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPEX11_YEAST
AccessioniPrimary (citable) accession number: Q12462
Secondary accession number(s): D6W1S2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 126 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1630 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.