Q12407 (YD199_YEAST) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 91.
History...
Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Putative metabolite transport protein YDL199C | ||||
| Gene names |
| ||||
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | ||||
| Taxonomic identifier | 559292 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 687 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Subcellular location | |
| Sequence similarities | Belongs to the major facilitator superfamily. Sugar transporter family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Transport |
| Cellular component | Membrane |
| Domain | Transmembrane Transmembrane helix |
| PTM | Phosphoprotein |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Cellular component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | protein binding Inferred from physical interaction. Source: IntAct substrate-specific transmembrane transporter activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Binary interactions
With | Entry | #Exp. | IntAct | Notes |
|---|---|---|---|---|
| HSP82 | P02829 | 2 | EBI-33162,EBI-8659 |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 687 | 687 | Putative metabolite transport protein YDL199C | PRO_0000242140 | |||||
Regions | |||||||||
| Topological domain | 1 – 122 | 122 | Extracellular Potential | ||||||
| Transmembrane | 123 – 143 | 21 | Helical; Potential | ||||||
| Topological domain | 144 – 164 | 21 | Cytoplasmic Potential | ||||||
| Transmembrane | 165 – 185 | 21 | Helical; Potential | ||||||
| Topological domain | 186 – 192 | 7 | Extracellular Potential | ||||||
| Transmembrane | 193 – 213 | 21 | Helical; Potential | ||||||
| Topological domain | 214 – 216 | 3 | Cytoplasmic Potential | ||||||
| Transmembrane | 217 – 237 | 21 | Helical; Potential | ||||||
| Topological domain | 238 – 251 | 14 | Extracellular Potential | ||||||
| Transmembrane | 252 – 272 | 21 | Helical; Potential | ||||||
| Topological domain | 273 – 283 | 11 | Cytoplasmic Potential | ||||||
| Transmembrane | 284 – 304 | 21 | Helical; Potential | ||||||
| Topological domain | 305 – 410 | 106 | Extracellular Potential | ||||||
| Transmembrane | 411 – 431 | 21 | Helical; Potential | ||||||
| Topological domain | 432 – 439 | 8 | Cytoplasmic Potential | ||||||
| Transmembrane | 440 – 460 | 21 | Helical; Potential | ||||||
| Topological domain | 461 – 469 | 9 | Extracellular Potential | ||||||
| Transmembrane | 470 – 490 | 21 | Helical; Potential | ||||||
| Topological domain | 491 – 500 | 10 | Cytoplasmic Potential | ||||||
| Transmembrane | 501 – 521 | 21 | Helical; Potential | ||||||
| Topological domain | 522 – 533 | 12 | Extracellular Potential | ||||||
| Transmembrane | 534 – 554 | 21 | Helical; Potential | ||||||
| Topological domain | 555 – 687 | 133 | Cytoplasmic Potential | ||||||
Amino acid modifications | |||||||||
| Modified residue | 534 | 1 | Phosphotyrosine Ref.6 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "New open reading frames, one of which is similar to the nifV gene of Azotobacter vinelandii, found on a 12.5 kbp fragment of chromosome IV of Saccharomyces cerevisiae." Verhasselt P., Voet M., Volckaert G. Yeast 11:961-966(1995) [PubMed: 8533471] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679. |
| [2] | "The nucleotide sequence of a 39 kb segment of yeast chromosome IV: 12 new open reading frames, nine known genes and one gene for Gly-tRNA." Bahr A., Moeller-Rieker S., Hankeln T., Kraemer C., Protin U., Schmidt E.R. Yeast 13:163-169(1997) [PubMed: 9046097] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679. |
| [3] | "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV." Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T. Zaccaria P.Nature 387:75-78(1997) [PubMed: 9169867] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c. |
| [4] | Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c. |
| [5] | "A global topology map of the Saccharomyces cerevisiae membrane proteome." Kim H., Melen K., Oesterberg M., von Heijne G. Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed: 16847258] [Abstract] Cited for: TOPOLOGY [LARGE SCALE ANALYSIS]. Strain: ATCC 208353 / W303-1A. |
| [6] | "A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-534, MASS SPECTROMETRY. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | X83276 Genomic DNA. Translation: CAA58248.1. X99000 Genomic DNA. Translation: CAA67470.1. Z74247 Genomic DNA. Translation: CAA98776.1. BK006938 Genomic DNA. Translation: DAA11665.1. |
| PIR | S58778. |
| RefSeq | NP_010082.1. NM_001180259.1. |
3D structure databases | |
| ProteinModelPortal | Q12407. |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP-8956N. |
| IntAct | Q12407. 2 interactions. |
| MINT | MINT-2491777. |
| STRING | Q12407. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblFungi | YDL199C; YDL199C; YDL199C. |
| GeneID | 851328. |
| KEGG | sce:YDL199C. |
| NMPDR | fig|4932.3.peg.815. |
Organism-specific databases | |
| CYGD | YDL199c. |
| SGD | S000002358. YDL199C. |
Phylogenomic databases | |
| eggNOG | fuNOG06872. |
| GeneTree | EFGT00070000008780. |
| OMA | DVEDDHA. |
| OrthoDB | EOG4DJP4W. |
Gene expression databases | |
| ArrayExpress | Q12407. |
| Genevestigator | Q12407. |
| GermOnline | YDL199C. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR020846. MFS_dom. IPR016196. MFS_dom_general_subst_transpt. IPR005828. Sub_transporter. IPR003663. Sugar/inositol_transpt. IPR005829. Sugar_transporter_CS. [Graphical view] |
| Pfam | PF00083. Sugar_tr. 1 hit. [Graphical view] |
| PRINTS | PR00171. SUGRTRNSPORT. |
| SUPFAM | SSF103473. MFS_gen_substrate_transporter. 1 hit. |
| PROSITE | PS50850. MFS. 1 hit. PS00217. SUGAR_TRANSPORT_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 968384. |
Entry information
| Entry name | YD199_YEAST | ||||||||
| Accession | Primary (citable) accession number: Q12407 Secondary accession number(s): D6VRF5 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| SIMILARITY comments Index of protein domains and families |

Clusters with