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Protein

Protein YOP1

Gene

YOP1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in membrane/vesicle trafficking.1 Publication

Miscellaneous

Present with 1759 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • endoplasmic reticulum inheritance Source: UniProtKB
  • endoplasmic reticulum organization Source: SGD
  • endoplasmic reticulum tubular network organization Source: UniProtKB
  • ER-dependent peroxisome organization Source: SGD
  • nuclear pore complex assembly Source: SGD
  • response to endoplasmic reticulum stress Source: SGD
  • vesicle-mediated transport Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-34187-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein YOP1
Alternative name(s):
YIP1 partner protein 1
YPT-interacting protein 2
Gene namesi
Name:YOP1
Synonyms:YIP2
Ordered Locus Names:YPR028W
ORF Names:YP9367.08
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi

Organism-specific databases

EuPathDBiFungiDB:YPR028W
SGDiS000006232 YOP1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei39 – 59HelicalSequence analysisAdd BLAST21
Transmembranei61 – 81HelicalSequence analysisAdd BLAST21
Transmembranei89 – 109HelicalSequence analysisAdd BLAST21
Transmembranei110 – 130HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources1 Publication
ChainiPRO_00001018592 – 180Protein YOP1Add BLAST179

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineCombined sources1 Publication1

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiQ12402
PaxDbiQ12402
PRIDEiQ12402
TopDownProteomicsiQ12402

PTM databases

iPTMnetiQ12402

Interactioni

Subunit structurei

Interacts with YIP1.1 Publication

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi36206, 110 interactors
DIPiDIP-3914N
IntActiQ12402, 9 interactors
MINTiQ12402
STRINGi4932.YPR028W

Structurei

3D structure databases

ProteinModelPortaliQ12402
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni2 – 17Interaction with YIP11 PublicationAdd BLAST16

Sequence similaritiesi

Belongs to the DP1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00550000074535
HOGENOMiHOG000172351
InParanoidiQ12402
KOiK17279
OMAiLYYFPWY
OrthoDBiEOG092C4YDM

Family and domain databases

InterProiView protein in InterPro
IPR004345 TB2_DP1_HVA22
PANTHERiPTHR12300 PTHR12300, 1 hit
PfamiView protein in Pfam
PF03134 TB2_DP1_HVA22, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q12402-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEYASSIHS QMKQFDTKYS GNRILQQLEN KTNLPKSYLV AGLGFAYLLL
60 70 80 90 100
IFINVGGVGE ILSNFAGFVL PAYLSLVALK TPTSTDDTQL LTYWIVFSFL
110 120 130 140 150
SVIEFWSKAI LYLIPFYWFL KTVFLIYIAL PQTGGARMIY QKIVAPLTDR
160 170 180
YILRDVSKTE KDEIRASVNE ASKATGASVH
Length:180
Mass (Da):20,270
Last modified:January 23, 2007 - v3
Checksum:i6F1073444B653CCF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ007902 Genomic DNA Translation: CAA07720.1
Z71255 Genomic DNA Translation: CAA95024.1
Z49274 Genomic DNA Translation: CAA89282.1
BK006949 Genomic DNA Translation: DAA11454.1
PIRiS54502
RefSeqiNP_015353.1, NM_001184125.1

Genome annotation databases

EnsemblFungiiYPR028W; YPR028W; YPR028W
GeneIDi856140
KEGGisce:YPR028W

Entry informationi

Entry nameiYOP1_YEAST
AccessioniPrimary (citable) accession number: Q12402
Secondary accession number(s): D6W438
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 133 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names

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