Reviewed,
UniProtKB/Swiss-Prot Q12390 (GST2_YEAST)
Last modified
February 9, 2010.
Version 80.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Glutathione S-transferase 2 EC=2.5.1.18 Alternative name(s): GST-II | ||||||
| Gene names |
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| Organism | Saccharomyces cerevisiae (Baker's yeast) [Complete proteome] | ||||||
| Taxonomic identifier | 4932 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 233 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Catalytic activity | RX + glutathione = HX + R-S-glutathione. |
| Subunit structure | Homodimer. |
| Sequence similarities | Belongs to the GST superfamily. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain. |
Ontologies
| Keywords | |
|---|---|
| Molecular function | Transferase |
| Technical term | 3D-structure Complete proteome |
| Gene Ontology (GO) | |
| Biological process | glutathione metabolic process Ref.4 Inferred from direct assay. Source: SGD |
| Cellular component | mitochondrion Inferred from direct assay. Source: SGD |
| Molecular function | glutathione transferase activity Ref.4 Inferred from direct assay. Source: SGD |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Sequence of a 37 kb DNA fragment from chromosome XII of Saccharomyces cerevisiae including the subtelomeric region of the left arm." Wedler H., Wambutt R. Submitted (JAN-1995) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972. |
| [2] | "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII." Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H. Hoheisel J.D.Nature 387:87-90(1997) [PubMed: 9169871] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972. |
| [3] | "Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. LaBaer J.Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c. |
| [4] | "A novel membrane-bound glutathione S-transferase functions in the stationary phase of the yeast Saccharomyces cerevisiae." Choi J.H., Lou W., Vancura A. J. Biol. Chem. 273:29915-29922(1998) [PubMed: 9792709] [Abstract] Cited for: CHARACTERIZATION. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EMBL GenBank DDBJ | Z47973 Genomic DNA. Translation: CAA87997.1. Z73165 Genomic DNA. Translation: CAA97513.1. AY557940 Genomic DNA. Translation: AAS56266.1. | ||||||||||||||||||||||||
| PIR | S50960. | ||||||||||||||||||||||||
| RefSeq | NP_013040.1. | ||||||||||||||||||||||||
3D structure databases | |||||||||||||||||||||||||
| PDBe RCSB PDB PDBj |
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| ModBase | Search... | ||||||||||||||||||||||||
Protein-protein interaction databases | |||||||||||||||||||||||||
| DIP | DIP-2981N. | ||||||||||||||||||||||||
| IntAct | Q12390. 3 interactions. | ||||||||||||||||||||||||
| STRING | Q12390. | ||||||||||||||||||||||||
Proteomic databases | |||||||||||||||||||||||||
| PeptideAtlas | Q12390. | ||||||||||||||||||||||||
Genome annotation databases | |||||||||||||||||||||||||
| Ensembl | YLL060C; YLL060C; YLL060C; Saccharomyces cerevisiae. [Genome view] | ||||||||||||||||||||||||
| GeneID | 850666. | ||||||||||||||||||||||||
| KEGG | sce:YLL060C. | ||||||||||||||||||||||||
| NMPDR | fig|4932.3.peg.4031. | ||||||||||||||||||||||||
Organism-specific databases | |||||||||||||||||||||||||
| CYGD | YLL060c. | ||||||||||||||||||||||||
| SGD | S000003983. GTT2. | ||||||||||||||||||||||||
Phylogenomic databases | |||||||||||||||||||||||||
| eggNOG | fuNOG15693. | ||||||||||||||||||||||||
| HOGENOM | HBG753188. | ||||||||||||||||||||||||
| OMA | CEALRAW. | ||||||||||||||||||||||||
| OrthoDB | EOG9XWHF3. | ||||||||||||||||||||||||
| PhylomeDB | Q12390. | ||||||||||||||||||||||||
Enzyme and pathway databases | |||||||||||||||||||||||||
| BRENDA | 2.5.1.18. 250. | ||||||||||||||||||||||||
Gene expression databases | |||||||||||||||||||||||||
| ArrayExpress | Q12390. | ||||||||||||||||||||||||
| Genevestigator | Q12390. | ||||||||||||||||||||||||
| GermOnline | YLL060C. Saccharomyces cerevisiae. | ||||||||||||||||||||||||
Family and domain databases | |||||||||||||||||||||||||
| InterPro | IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR012336. Thioredoxin-like_fold. IPR012335. Thioredoxin_fold. [Graphical view] | ||||||||||||||||||||||||
| Gene3D | G3DSA:1.20.1050.10. GST_C_like. 1 hit. G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit. | ||||||||||||||||||||||||
| Pfam | PF00043. GST_C. 1 hit. PF02798. GST_N. 1 hit. [Graphical view] | ||||||||||||||||||||||||
| PROSITE | PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view] | ||||||||||||||||||||||||
| ProtoNet | Search... | ||||||||||||||||||||||||
Other Resources | |||||||||||||||||||||||||
| NextBio | 966644. | ||||||||||||||||||||||||
Entry information
| Entry name | GST2_YEAST | ||||||||
| Accession | Primary (citable) accession number: Q12390 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| PDB cross-references Index of Protein Data Bank (PDB) cross-references |
| SIMILARITY comments Index of protein domains and families |
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |

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