Reviewed, UniProtKB/Swiss-Prot Q12365 (BBP1_YEAST)

Names and origin

Protein names

Recommended name:
    Protein BBP1

Gene names

Name:	BBP1
Ordered Locus Names:	YPL255W
ORF Names:	P0745

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	385 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level.

General annotation (Comments)

Miscellaneous

Present with 922 molecules/cell in log phase SD medium. Ref.4

Ontologies

Keywords
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	microtubule nucleation Inferred from physical interaction. Source: SGD spindle pole body duplication in nuclear envelope Inferred from mutant phenotype. Source: SGD
Cellular component	spindle pole body Inferred from direct assay. Source: SGD
Molecular function	protein binding Inferred from physical interaction. Source: IntAct structural constituent of cytoskeleton Inferred from physical interaction. Source: SGD
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
ADY3	Q07732	1	EBI-3448,EBI-33406
BIT2	P38346	1	EBI-3448,EBI-21144
BOI2	P39969	1	EBI-3448,EBI-3727
ECM4	P36156	1	EBI-3448,EBI-2042717
MRP4	P32902	1	EBI-3448,EBI-16248
NBP1	P52919	1	EBI-3448,EBI-11886
NPR2	P39923	1	EBI-3448,EBI-12212
RVS167	P39743	1	EBI-3448,EBI-14500

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 385	385	Protein BBP1		PRO_0000064840
Amino acid modifications
	Modified residue	71	1	Phosphoserine Ref.7
	Modified residue	73	1	Phosphoserine Ref.7 Ref.5
	Modified residue	115	1	Phosphoserine Ref.6

Sequences

	Sequence		Length	Mass (Da)
	Q12365-1 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: 3A1A827E7664E4E0	FASTA	385	45,384
	10 20 30 40 50 60 MNQEDNTGGG GIFGLFKWTK DALFGTDISP SMKYKDQEER RDRSRYAQDD TNFSMKFGND 70 80 90 100 110 120 SNRRSTNLSR SNSWSGLDST LHRKYELLPE YNENGFNSIV NGDHHSKERI RSLRSPAPIV 130 140 150 160 170 180 PREPLRNEPT DTFGHRLHTK RRTINELSNS QIPFIPPQED DPLLSKLFNK DGVNEVRRSP 190 200 210 220 230 240 YKLSVKDIPG KFPSPLTKRD EIDNYYVRDE DACHKNREYK KAYFDLFAQM DLNSRDLEDL 250 260 270 280 290 300 CEDVREQREQ FHRNEQTYKQ AYEEMRAELV NELKKSKTLF ENYYSLGQKY KSLKKVLDQT 310 320 330 340 350 360 ISHEAELATS RERLYQEEDL KNFEIQTLKQ RLSDLELKYT NLQIEKDMQR DNYESEIHDL 370 380 LLQLSLRNNE RKDTSAGSNI FSTGQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Xue Z., Shan X., Melese T. Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI." Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M. , Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J. Nature 387:103-105(1997) [PubMed: 9169875] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[3]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[4]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]	"Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway." Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J., Mann M., Jensen O.N. Mol. Cell. Proteomics 4:310-327(2005) [PubMed: 15665377] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-73, MASS SPECTROMETRY.
[6]	"Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae." Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P. J. Proteome Res. 6:1190-1197(2007) [PubMed: 17330950] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-115, MASS SPECTROMETRY.
[7]	"A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-71 AND SER-73, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X92658 Genomic DNA. Translation: CAA63347.1. Z73610 Genomic DNA. Translation: CAA97980.1. Z73611 Genomic DNA. Translation: CAA97981.1. AY693019 Genomic DNA. Translation: AAT93038.1.
PIR	S61566.
RefSeq	NP_015068.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-4418N.
IntAct	Q12365. 17 interactions.
STRING	Q12365.
Proteomic databases
PRIDE	Q12365.
Genome annotation databases
Ensembl	YPL255W; YPL255W; YPL255W; Saccharomyces cerevisiae. [Genome view]
GeneID	855820.
KEGG	sce:YPL255W.
NMPDR	fig|4932.3.peg.6194.
Organism-specific databases
CYGD	YPL255w.
SGD	S000006176. BBP1.
Phylogenomic databases
eggNOG	fuNOG11882.
OMA	SRSNSWS.
OrthoDB	EOG9GTMW9.
PhylomeDB	Q12365.
Gene expression databases
ArrayExpress	Q12365.
Genevestigator	Q12365.
GermOnline	YPL255W. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other Resources
NextBio	980362.

Entry information

Entry name

BBP1_YEAST

Accession

Primary (citable) accession number: Q12365

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	January 19, 2010
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)