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Protein

Zinc finger transcription factor YRM1

Gene

YRM1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Transcription factor involved in the regulation of multidrug resistance genes. Acts in concert with YRR1.2 Publications

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi31 – 5929Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-33685-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger transcription factor YRM1
Alternative name(s):
Reveromycin resistance modulator 1
Gene namesi
Name:YRM1
Ordered Locus Names:YOR172W
ORF Names:O3620
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOR172W.
SGDiS000005698. YRM1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 786786Zinc finger transcription factor YRM1PRO_0000269650Add
BLAST

PTM databases

iPTMnetiQ12340.

Interactioni

Protein-protein interaction databases

BioGridi34566. 21 interactions.
DIPiDIP-4118N.
MINTiMINT-530627.

Structurei

3D structure databases

ProteinModelPortaliQ12340.
SMRiQ12340. Positions 25-94.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000010685.
HOGENOMiHOG000155687.
InParanoidiQ12340.
OMAiECENGER.
OrthoDBiEOG092C0IY5.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q12340-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKRGSLQDR ASPSEETVKK AQKRRKPIKS CAFCRKRKLR CDQQKPMCST
60 70 80 90 100
CKTRGRSGCL YTEKFTHKIE TKELFGSTPN IELLKRIEDL EKRLDDKELT
110 120 130 140 150
EKDVALSTSP FRNPYANFYY LQCKGSGRRI VYGPTSLRTH LSNDDNRFVN
160 170 180 190 200
TYNQLWSKVK IERNRWKARH KWTMKPETQL LEGPPLEKTG SDILQQVCNV
210 220 230 240 250
LPSFEQSSKI ITDFFNTELE TNEVSEVLDK TKIINDFTSS FLPSDELLPN
260 270 280 290 300
GERRIEKLLP STKKNYYKIG VILMILCIRH FYKNTPEEIE KFLIMLTGLS
310 320 330 340 350
TAKVYFIERA QFLLLKYYHR ELIWACGDDS HMISLVDLLC STAIMLGLHL
360 370 380 390 400
NIREIYKNQE NIVGSMESLE NLWVWIILSD FNVSLNIGRC LAINSSYFQV
410 420 430 440 450
DECENGERLP KNTNNYSSTV FFDQSNSCMG KLKRFLRLAR PMLDQIYDRS
460 470 480 490 500
AFPDLAENCK KLRNFVETEF HPISYYTDSE LISKVPLCEI KVLAQVLNLL
510 520 530 540 550
LTFYSLRYLI YKEKSVVLEN NILQTILVSF SLVINTTILC FNLDEKHFPE
560 570 580 590 600
FFDHNCVHLP PFMALSLVYT NFLFPRASTG FCAFLYHKLT LFEKGYYLSS
610 620 630 640 650
NIKDQEVTDW DLSTLNIPLD KAMNLLTAFK IHSDIFAKWS NDNNKQLRII
660 670 680 690 700
MARSYTFVIN IALESIYRAV LEKVIKYRTE VENTWLQQLQ DELNGSYSLT
710 720 730 740 750
DNVNTPIDPS LSDLGVTSAS PLAGNSPGLP PEEVRNNSEN ASHNNETGPI
760 770 780
ETELAQTISN EFWTAYNLGW EELMSQPDYK YLFDTQ
Length:786
Mass (Da):91,084
Last modified:November 1, 1996 - v1
Checksum:i3096ABD7AAF9B553
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti158 – 1581K → Q in AAT92726 (PubMed:17322287).Curated
Sequence conflicti604 – 6041D → G in AAT92726 (PubMed:17322287).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U55021 Genomic DNA. Translation: AAB47417.1.
Z75080 Genomic DNA. Translation: CAA99380.1.
Z75081 Genomic DNA. Translation: CAA99382.1.
AY692707 Genomic DNA. Translation: AAT92726.1.
BK006948 Genomic DNA. Translation: DAA10944.1.
PIRiS67060.
RefSeqiNP_014815.3. NM_001183591.3.

Genome annotation databases

EnsemblFungiiYOR172W; YOR172W; YOR172W.
GeneIDi854343.
KEGGisce:YOR172W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U55021 Genomic DNA. Translation: AAB47417.1.
Z75080 Genomic DNA. Translation: CAA99380.1.
Z75081 Genomic DNA. Translation: CAA99382.1.
AY692707 Genomic DNA. Translation: AAT92726.1.
BK006948 Genomic DNA. Translation: DAA10944.1.
PIRiS67060.
RefSeqiNP_014815.3. NM_001183591.3.

3D structure databases

ProteinModelPortaliQ12340.
SMRiQ12340. Positions 25-94.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34566. 21 interactions.
DIPiDIP-4118N.
MINTiMINT-530627.

PTM databases

iPTMnetiQ12340.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYOR172W; YOR172W; YOR172W.
GeneIDi854343.
KEGGisce:YOR172W.

Organism-specific databases

EuPathDBiFungiDB:YOR172W.
SGDiS000005698. YRM1.

Phylogenomic databases

GeneTreeiENSGT00390000010685.
HOGENOMiHOG000155687.
InParanoidiQ12340.
OMAiECENGER.
OrthoDBiEOG092C0IY5.

Enzyme and pathway databases

BioCyciYEAST:G3O-33685-MONOMER.

Miscellaneous databases

PROiQ12340.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYRM1_YEAST
AccessioniPrimary (citable) accession number: Q12340
Secondary accession number(s): D6W2M8, E9PAH0, Q6B2M3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 125 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.