Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Zinc finger transcription factor YRM1

Gene

YRM1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Transcription factor involved in the regulation of multidrug resistance genes. Acts in concert with YRR1.2 Publications

Miscellaneous

Present with 125 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi31 – 59Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd BLAST29

GO - Molecular functioni

GO - Biological processi

  • regulation of transcription from RNA polymerase II promoter Source: SGD

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-33685-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger transcription factor YRM1
Alternative name(s):
Reveromycin resistance modulator 1
Gene namesi
Name:YRM1
Ordered Locus Names:YOR172W
ORF Names:O3620
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOR172W.
SGDiS000005698. YRM1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002696501 – 786Zinc finger transcription factor YRM1Add BLAST786

Proteomic databases

PRIDEiQ12340.

PTM databases

iPTMnetiQ12340.

Interactioni

Protein-protein interaction databases

BioGridi34566. 34 interactors.
DIPiDIP-4118N.
IntActiQ12340. 9 interactors.
MINTiMINT-530627.
STRINGi4932.YOR172W.

Structurei

3D structure databases

ProteinModelPortaliQ12340.
SMRiQ12340.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000010685.
HOGENOMiHOG000155687.
InParanoidiQ12340.
OMAiECENGER.
OrthoDBiEOG092C0IY5.

Family and domain databases

CDDicd00067. GAL4. 1 hit.
Gene3Di4.10.240.10. 1 hit.
InterProiView protein in InterPro
IPR001138. Zn2-C6_fun-type_DNA-bd.
PfamiView protein in Pfam
PF00172. Zn_clus. 1 hit.
SMARTiView protein in SMART
SM00066. GAL4. 1 hit.
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiView protein in PROSITE
PS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q12340-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKRGSLQDR ASPSEETVKK AQKRRKPIKS CAFCRKRKLR CDQQKPMCST
60 70 80 90 100
CKTRGRSGCL YTEKFTHKIE TKELFGSTPN IELLKRIEDL EKRLDDKELT
110 120 130 140 150
EKDVALSTSP FRNPYANFYY LQCKGSGRRI VYGPTSLRTH LSNDDNRFVN
160 170 180 190 200
TYNQLWSKVK IERNRWKARH KWTMKPETQL LEGPPLEKTG SDILQQVCNV
210 220 230 240 250
LPSFEQSSKI ITDFFNTELE TNEVSEVLDK TKIINDFTSS FLPSDELLPN
260 270 280 290 300
GERRIEKLLP STKKNYYKIG VILMILCIRH FYKNTPEEIE KFLIMLTGLS
310 320 330 340 350
TAKVYFIERA QFLLLKYYHR ELIWACGDDS HMISLVDLLC STAIMLGLHL
360 370 380 390 400
NIREIYKNQE NIVGSMESLE NLWVWIILSD FNVSLNIGRC LAINSSYFQV
410 420 430 440 450
DECENGERLP KNTNNYSSTV FFDQSNSCMG KLKRFLRLAR PMLDQIYDRS
460 470 480 490 500
AFPDLAENCK KLRNFVETEF HPISYYTDSE LISKVPLCEI KVLAQVLNLL
510 520 530 540 550
LTFYSLRYLI YKEKSVVLEN NILQTILVSF SLVINTTILC FNLDEKHFPE
560 570 580 590 600
FFDHNCVHLP PFMALSLVYT NFLFPRASTG FCAFLYHKLT LFEKGYYLSS
610 620 630 640 650
NIKDQEVTDW DLSTLNIPLD KAMNLLTAFK IHSDIFAKWS NDNNKQLRII
660 670 680 690 700
MARSYTFVIN IALESIYRAV LEKVIKYRTE VENTWLQQLQ DELNGSYSLT
710 720 730 740 750
DNVNTPIDPS LSDLGVTSAS PLAGNSPGLP PEEVRNNSEN ASHNNETGPI
760 770 780
ETELAQTISN EFWTAYNLGW EELMSQPDYK YLFDTQ
Length:786
Mass (Da):91,084
Last modified:November 1, 1996 - v1
Checksum:i3096ABD7AAF9B553
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti158K → Q in AAT92726 (PubMed:17322287).Curated1
Sequence conflicti604D → G in AAT92726 (PubMed:17322287).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U55021 Genomic DNA. Translation: AAB47417.1.
Z75080 Genomic DNA. Translation: CAA99380.1.
Z75081 Genomic DNA. Translation: CAA99382.1.
AY692707 Genomic DNA. Translation: AAT92726.1.
BK006948 Genomic DNA. Translation: DAA10944.1.
PIRiS67060.
RefSeqiNP_014815.3. NM_001183591.3.

Genome annotation databases

EnsemblFungiiYOR172W; YOR172W; YOR172W.
GeneIDi854343.
KEGGisce:YOR172W.

Similar proteinsi

Entry informationi

Entry nameiYRM1_YEAST
AccessioniPrimary (citable) accession number: Q12340
Secondary accession number(s): D6W2M8, E9PAH0, Q6B2M3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: November 1, 1996
Last modified: September 27, 2017
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names