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Protein

Protoplast secreted protein 2

Gene

PST2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 2330 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

Enzyme and pathway databases

BioCyciYEAST:G3O-29647-MONOMER.

Protein family/group databases

CAZyiAA6. Auxiliary Activities 6.

Names & Taxonomyi

Protein namesi
Recommended name:
Protoplast secreted protein 2
Gene namesi
Name:PST2
Ordered Locus Names:YDR032C
ORF Names:D3422, YD9673.02C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR032C.
SGDiS000002439. PST2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000004148222 – 198Protoplast secreted protein 2Add BLAST177

Proteomic databases

MaxQBiQ12335.
PRIDEiQ12335.
TopDownProteomicsiQ12335.

PTM databases

iPTMnetiQ12335.

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

BioGridi32081. 127 interactors.
DIPiDIP-1762N.
IntActiQ12335. 48 interactors.
MINTiMINT-399440.
STRINGi4932.YDR032C.

Structurei

Secondary structure

1198
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 8Combined sources6
Beta strandi11 – 13Combined sources3
Helixi14 – 28Combined sources15
Beta strandi32 – 38Combined sources7
Helixi44 – 50Combined sources7
Helixi63 – 68Combined sources6
Beta strandi70 – 77Combined sources8
Beta strandi79 – 82Combined sources4
Helixi85 – 92Combined sources8
Helixi95 – 99Combined sources5
Turni100 – 105Combined sources6
Beta strandi107 – 117Combined sources11
Turni118 – 121Combined sources4
Helixi122 – 125Combined sources4
Helixi128 – 134Combined sources7
Helixi144 – 146Combined sources3
Helixi147 – 150Combined sources4
Beta strandi163 – 167Combined sources5
Beta strandi170 – 172Combined sources3
Helixi178 – 197Combined sources20

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5MP4X-ray2.79A/B/C/D/E/F/G/H1-198[»]
ProteinModelPortaliQ12335.
SMRiQ12335.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 191Flavodoxin-likePROSITE-ProRule annotationAdd BLAST170

Sequence similaritiesi

Belongs to the WrbA family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

GeneTreeiENSGT00390000012243.
HOGENOMiHOG000030539.
InParanoidiQ12335.
OMAiVGVPYAC.
OrthoDBiEOG092C4TWB.

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
InterProiView protein in InterPro
IPR008254. Flavodoxin/NO_synth.
IPR029039. Flavoprotein-like_dom.
IPR010089. Flavoprotein_WrbA-like.
IPR005025. FMN_Rdtase-like.
PfamiView protein in Pfam
PF03358. FMN_red. 1 hit.
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR01755. flav_wrbA. 1 hit.
PROSITEiView protein in PROSITE
PS50902. FLAVODOXIN_LIKE. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q12335-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRVAIIIYT LYGHVAATAE AEKKGIEAAG GSADIYQVEE TLSPEVVKAL
60 70 80 90 100
GGAPKPDYPI ATQDTLTEYD AFLFGIPTRF GNFPAQWKAF WDRTGGLWAK
110 120 130 140 150
GALHGKVAGC FVSTGTGGGN EATIMNSLST LAHHGIIFVP LGYKNVFAEL
160 170 180 190
TNMDEVHGGS PWGAGTIAGS DGSRSPSALE LQVHEIQGKT FYETVAKF
Length:198
Mass (Da):20,966
Last modified:November 1, 1996 - v1
Checksum:i1056E7A1F3E82288
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z74328 Genomic DNA. Translation: CAA98854.1.
Z68196 Genomic DNA. Translation: CAA92369.1.
AY557646 Genomic DNA. Translation: AAS55972.1.
BK006938 Genomic DNA. Translation: DAA11876.1.
PIRiS61585.
RefSeqiNP_010315.1. NM_001180340.1.

Genome annotation databases

EnsemblFungiiYDR032C; YDR032C; YDR032C.
GeneIDi851596.
KEGGisce:YDR032C.

Similar proteinsi

Entry informationi

Entry nameiPST2_YEAST
AccessioniPrimary (citable) accession number: Q12335
Secondary accession number(s): D6VS16
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: November 1, 1996
Last modified: October 25, 2017
This is version 153 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names