ID   YD061_YEAST             Reviewed;         539 AA.
AC   Q12298;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   07-JUL-2009, entry version 66.
DE   RecName: Full=Uncharacterized ABC transporter ATP-binding protein YDR061W;
GN   OrderedLocusNames=YDR061W; ORFNames=D4241;
OS   Saccharomyces cerevisiae (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=4932;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   MEDLINE=96381250; PubMed=8789263;
RX   DOI=10.1002/(SICI)1097-0061(199601)12:1<85::AID-YEA890>3.0.CO;2-U;
RA   Brandt P., Ramlow S., Otto B., Bloecker H.;
RT   "Nucleotide sequence analysis of a 32,500 bp region of the right arm
RT   of Saccharomyces cerevisiae chromosome IV.";
RL   Yeast 12:85-90(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   MEDLINE=97313263; PubMed=9169867;
RA   Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G.,
RA   Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C.,
RA   Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F.,
RA   Delaveau T., del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M.,
RA   Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T.,
RA   Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C.,
RA   Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S.,
RA   Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N.,
RA   Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M.,
RA   Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L.,
RA   Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M.,
RA   Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S.,
RA   Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M.,
RA   Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S.,
RA   Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K.,
RA   Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D.,
RA   Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C.,
RA   Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T.,
RA   Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E.,
RA   Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W.,
RA   Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K.,
RA   Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S.,
RA   Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A.,
RA   Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R.,
RA   Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S.,
RA   Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M.,
RA   Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y.,
RA   Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M.,
RA   Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E.,
RA   Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R.,
RA   Waterston R., Albermann K., Hani J., Heumann K., Kleine K.,
RA   Mewes H.-W., Zollner A., Zaccaria P.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.";
RL   Nature 387:75-78(1997).
RN   [3]
RP   INDUCTION.
RX   PubMed=14512416; DOI=10.1074/jbc.M309580200;
RA   Lucau-Danila A., Delaveau T., Lelandais G., Devaux F., Jacq C.;
RT   "Competitive promoter occupancy by two yeast paralogous transcription
RT   factors controlling the multidrug resistance phenomenon.";
RL   J. Biol. Chem. 278:52641-52650(2003).
RN   [4]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   MEDLINE=22923954; PubMed=14562095; DOI=10.1038/nature02026;
RA   Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA   Weissman J.S., O'Shea E.K.;
RT   "Global analysis of protein localization in budding yeast.";
RL   Nature 425:686-691(2003).
RN   [5]
RP   LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX   MEDLINE=22923965; PubMed=14562106; DOI=10.1038/nature02046;
RA   Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A.,
RA   Dephoure N., O'Shea E.K., Weissman J.S.;
RT   "Global analysis of protein expression in yeast.";
RL   Nature 425:737-741(2003).
CC   -!- INTERACTION:
CC       P43582:-; NbExp=1; IntAct=EBI-34580, EBI-22766;
CC       P00330:ADH1; NbExp=1; IntAct=EBI-34580, EBI-2218;
CC       P22696:ESS1; NbExp=1; IntAct=EBI-34580, EBI-6679;
CC       P33203:PRP40; NbExp=1; IntAct=EBI-34580, EBI-701;
CC       P39940:RSP5; NbExp=1; IntAct=EBI-34580, EBI-16219;
CC       Q06525:URN1; NbExp=1; IntAct=EBI-34580, EBI-35138;
CC   -!- SUBCELLULAR LOCATION: Mitochondrion.
CC   -!- INDUCTION: Induced by transcription factor YRM1.
CC   -!- MISCELLANEOUS: Present with 1580 molecules/cell in log phase SD
CC       medium.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC   -!- SIMILARITY: Contains 2 ABC transporter domains.
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DR   EMBL; X84162; CAA58977.1; -; Genomic_DNA.
DR   EMBL; Z49209; CAA89090.1; -; Genomic_DNA.
DR   EMBL; Z74357; CAA98879.1; -; Genomic_DNA.
DR   PIR; S54045; S54045.
DR   RefSeq; NP_010346.1; -.
DR   DIP; DIP:1817N; -.
DR   IntAct; Q12298; 9.
DR   PeptideAtlas; Q12298; -.
DR   Ensembl; YDR061W; Saccharomyces cerevisiae.
DR   GeneID; 851633; -.
DR   GenomeReviews; Z71256_GR; YDR061W.
DR   KEGG; sce:YDR061W; -.
DR   NMPDR; fig|4932.3.peg.1091; -.
DR   CYGD; YDR061w; -.
DR   SGD; S000002468; YDR061W.
DR   HOGENOM; Q12298; -.
DR   OMA; Q12298; WINSLSN.
DR   NextBio; 969185; -.
DR   GermOnline; YDR061W; Saccharomyces cerevisiae.
DR   GO; GO:0005739; C:mitochondrion; IDA:SGD.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR017871; ABC_transporter_CS.
DR   InterPro; IPR003593; ATPase_AAA+_core.
DR   Pfam; PF00005; ABC_tran; 2.
DR   ProDom; PD000006; ABC_transporter; 1.
DR   SMART; SM00382; AAA; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; FALSE_NEG.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   1: Evidence at protein level;
KW   ATP-binding; Complete proteome; Mitochondrion; Nucleotide-binding;
KW   Repeat; Transport.
FT   CHAIN         1    539       Uncharacterized ABC transporter ATP-
FT                                binding protein YDR061W.
FT                                /FTId=PRO_0000244440.
FT   DOMAIN        8    265       ABC transporter 1.
FT   DOMAIN      307    537       ABC transporter 2.
FT   NP_BIND     339    346       ATP (Potential).
SQ   SEQUENCE   539 AA;  61191 MW;  3F27AF363EBED838 CRC64;
     MSTNKFVVRI TNALFKSSLA SNSPPVYPKR IRHFEILPNE KWVIWGPGKG KFLDVLNNKY
     ICEPPLSLRF GFLKESSNIL PRIEQVAFKG VMPTAHLSAR YEYFKDDYDQ TCKQFIFDKA
     SGSNAVSYKV ETNNRQINME LYNALVENLN LSSLQDRWVM GLSNGQMRRA RLARSILKEP
     DLLLIDDPFL GLDPAAIATI SQFLAKYDSI EVSGGCPIVI GLRYQDTIPA WCTHICCVDE
     KNGILFEGPI EKLQSKMDET RSRALKELEQ LKKASNSKED ISINDLICIH PMYGKKEHEI
     IKMPHLIELD GLSVSYKGEA VLENLHWKVQ PGSKWHIRGD NGSGKSTLLS LLTAEHPQSW
     NSRVIDNGVP RRTGKTNYFD LNSKIGMSSP ELHAIFLKNA GGRLNIRESV ATGYHEASSN
     NYLPIWKRLD KNSQEIVNMY LKYFGLDKDA DSVLFEQLSV SDQKLVLFVR SLIKMPQILI
     LDEAFSGMEV EPMMRCHEFL EEWPGTVLVV AHVAEETPKC AHYLRLISPG EYEIGDMEN
//