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Q12298 (YD061_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized ABC transporter ATP-binding protein YDR061W
Gene names
Ordered Locus Names:YDR061W
ORF Names:D4241
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length539 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Mitochondrion Ref.5.

Induction

Induced by transcription factor YRM1. Ref.4

Miscellaneous

Present with 1580 molecules/cell in log phase SD medium. Ref.6

Sequence similarities

Belongs to the ABC transporter superfamily.

Contains 2 ABC transporter domains.

Ontologies

Keywords
   Cellular componentMitochondrion
   DomainRepeat
   LigandATP-binding
Nucleotide-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentmitochondrion

Inferred from direct assay Ref.5. Source: SGD

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

ATPase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 539539Uncharacterized ABC transporter ATP-binding protein YDR061W
PRO_0000244440

Regions

Domain8 – 265258ABC transporter 1
Domain307 – 537231ABC transporter 2
Nucleotide binding339 – 3468ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q12298 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 3F27AF363EBED838

FASTA53961,191
        10         20         30         40         50         60 
MSTNKFVVRI TNALFKSSLA SNSPPVYPKR IRHFEILPNE KWVIWGPGKG KFLDVLNNKY 

        70         80         90        100        110        120 
ICEPPLSLRF GFLKESSNIL PRIEQVAFKG VMPTAHLSAR YEYFKDDYDQ TCKQFIFDKA 

       130        140        150        160        170        180 
SGSNAVSYKV ETNNRQINME LYNALVENLN LSSLQDRWVM GLSNGQMRRA RLARSILKEP 

       190        200        210        220        230        240 
DLLLIDDPFL GLDPAAIATI SQFLAKYDSI EVSGGCPIVI GLRYQDTIPA WCTHICCVDE 

       250        260        270        280        290        300 
KNGILFEGPI EKLQSKMDET RSRALKELEQ LKKASNSKED ISINDLICIH PMYGKKEHEI 

       310        320        330        340        350        360 
IKMPHLIELD GLSVSYKGEA VLENLHWKVQ PGSKWHIRGD NGSGKSTLLS LLTAEHPQSW 

       370        380        390        400        410        420 
NSRVIDNGVP RRTGKTNYFD LNSKIGMSSP ELHAIFLKNA GGRLNIRESV ATGYHEASSN 

       430        440        450        460        470        480 
NYLPIWKRLD KNSQEIVNMY LKYFGLDKDA DSVLFEQLSV SDQKLVLFVR SLIKMPQILI 

       490        500        510        520        530 
LDEAFSGMEV EPMMRCHEFL EEWPGTVLVV AHVAEETPKC AHYLRLISPG EYEIGDMEN

« Hide

References

« Hide 'large scale' references
[1]"Nucleotide sequence analysis of a 32,500 bp region of the right arm of Saccharomyces cerevisiae chromosome IV."
Brandt P., Ramlow S., Otto B., Bloecker H.
Yeast 12:85-90(1996) [PubMed: 8789263] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T. expand/collapse author list , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
Nature 387:75-78(1997) [PubMed: 9169867] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Competitive promoter occupancy by two yeast paralogous transcription factors controlling the multidrug resistance phenomenon."
Lucau-Danila A., Delaveau T., Lelandais G., Devaux F., Jacq C.
J. Biol. Chem. 278:52641-52650(2003) [PubMed: 14512416] [Abstract]
Cited for: INDUCTION.
[5]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed: 14562095] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[6]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed: 14562106] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		X84162 Genomic DNA. Translation: CAA58977.1.
Z49209 Genomic DNA. Translation: CAA89090.1.
Z74357 Genomic DNA. Translation: CAA98879.1.
BK006938 Genomic DNA. Translation: DAA11907.1.
PIRS54045.
RefSeqNP_010346.1. NM_001180369.1.

3D structure databases

ProteinModelPortalQ12298.
SMRQ12298. Positions 32-57, 144-239, 302-536.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-1817N.
IntActQ12298. 8 interactions.
MINTMINT-391320.
STRINGQ12298.

Proteomic databases

PeptideAtlasQ12298.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYDR061W; YDR061W; YDR061W.
GeneID851633.
KEGGsce:YDR061W.
NMPDRfig|4932.3.peg.1091.

Organism-specific databases

CYGDYDR061w.
SGDS000002468. YDR061W.

Phylogenomic databases

eggNOGfuNOG04111.
GeneTreeEFGT00050000001695.
HOGENOMHBG395833.
OMACLELAKQ.
OrthoDBEOG4H49CB.

Gene expression databases

ArrayExpressQ12298.
GenevestigatorQ12298.
GermOnlineYDR061W. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR003439. ABC_transporter-like.
IPR003593. ATPase_AAA+_core.
[Graphical view]
PfamPF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
PROSITEPS00211. ABC_TRANSPORTER_1. False negative.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio969185.

Entry information

Entry nameYD061_YEAST
AccessionPrimary (citable) accession number: Q12298
Secondary accession number(s): D6VS47
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 1, 1996
Last modified: December 14, 2011
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents