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Protein

Sterol uptake protein 2

Gene

SUT2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Putative transcription factor involved in the regulation of the activity of the cAMP/protein kinase A pathway. Involved in sterol uptake.2 Publications

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Enzyme and pathway databases

BioCyciYEAST:G3O-34171-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Sterol uptake protein 2
Gene namesi
Name:SUT2
Ordered Locus Names:YPR009W
ORF Names:LPZ9w
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPR009W.
SGDiS000006213. SUT2.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001150151 – 268Sterol uptake protein 2Add BLAST268

Proteomic databases

PRIDEiQ12286.

Interactioni

GO - Molecular functioni

  • RNA polymerase II repressing transcription factor binding Source: SGD

Protein-protein interaction databases

BioGridi36187. 53 interactors.

Structurei

3D structure databases

ProteinModelPortaliQ12286.
SMRiQ12286.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SUT1 family.Curated

Phylogenomic databases

GeneTreeiENSGT00530000067177.
InParanoidiQ12286.
OrthoDBiEOG092C5UCP.

Family and domain databases

Gene3Di4.10.240.10. 2 hits.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q12286-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPNNRTCDV ITNKDESLPA LLLPALNSYT CDDSLLKGQI SSNGRYQPFG
60 70 80 90 100
FSDCSLLPKR LNIQAGQGSM PVSSIQCADH SYSNWQKESE KTKLPKLGCP
110 120 130 140 150
TEYTEYYKTV SSGETTDSAV VSSIATNRLK RKRQRDGPSC DSCRIKKIKC
160 170 180 190 200
NATIIIFLQD RNLISSISSN LHYTLSQDDI NQFRMKFFRK LPDVMGTYEV
210 220 230 240 250
IKHLDKIVLF KACTSCSRRN QKNGKCLFSR GFTKSDMNVF PKINSKLKDK
260
SIFEMTVDDY VAAGFQTL
Length:268
Mass (Da):30,258
Last modified:November 1, 1996 - v1
Checksum:i69B89766F75FDBAE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U31900 Genomic DNA. Translation: AAA97588.1.
Z49919 Genomic DNA. Translation: CAA90153.1.
Z71255 Genomic DNA. Translation: CAA95049.1.
BK006949 Genomic DNA. Translation: DAA11436.1.
PIRiS57542.
RefSeqiNP_015334.1. NM_001184106.1.

Genome annotation databases

EnsemblFungiiYPR009W; YPR009W; YPR009W.
GeneIDi856118.
KEGGisce:YPR009W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U31900 Genomic DNA. Translation: AAA97588.1.
Z49919 Genomic DNA. Translation: CAA90153.1.
Z71255 Genomic DNA. Translation: CAA95049.1.
BK006949 Genomic DNA. Translation: DAA11436.1.
PIRiS57542.
RefSeqiNP_015334.1. NM_001184106.1.

3D structure databases

ProteinModelPortaliQ12286.
SMRiQ12286.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36187. 53 interactors.

Proteomic databases

PRIDEiQ12286.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYPR009W; YPR009W; YPR009W.
GeneIDi856118.
KEGGisce:YPR009W.

Organism-specific databases

EuPathDBiFungiDB:YPR009W.
SGDiS000006213. SUT2.

Phylogenomic databases

GeneTreeiENSGT00530000067177.
InParanoidiQ12286.
OrthoDBiEOG092C5UCP.

Enzyme and pathway databases

BioCyciYEAST:G3O-34171-MONOMER.

Miscellaneous databases

PROiQ12286.

Family and domain databases

Gene3Di4.10.240.10. 2 hits.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSUT2_YEAST
AccessioniPrimary (citable) accession number: Q12286
Secondary accession number(s): D6W420
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.