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Protein

Uncharacterized transcriptional regulatory protein YLL054C

Gene

YLL054C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Required for growth on non-fermentable carbon sources.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi15 – 4228Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-32153-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized transcriptional regulatory protein YLL054C
Gene namesi
Ordered Locus Names:YLL054C
ORF Names:L0584
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XII

Organism-specific databases

EuPathDBiFungiDB:YLL054C.
SGDiS000003977. YLL054C.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 843843Uncharacterized transcriptional regulatory protein YLL054CPRO_0000247135Add
BLAST

Proteomic databases

MaxQBiQ12244.

PTM databases

iPTMnetiQ12244.

Interactioni

Protein-protein interaction databases

BioGridi31261. 17 interactions.
DIPiDIP-5612N.
IntActiQ12244. 1 interaction.
MINTiMINT-480719.

Structurei

3D structure databases

ProteinModelPortaliQ12244.
SMRiQ12244. Positions 12-50.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000000033.
InParanoidiQ12244.
OMAiCIHERIL.
OrthoDBiEOG7673K6.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q12244-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIASQKKVK PSFVCLRCKQ RKIKCDKLWP TCSKCKASSS ICSYEVEPGR
60 70 80 90 100
INKSPTIENA PHRDIRNITP ASMSASGSFT SILNPSTKDW EMKNFAMNLS
110 120 130 140 150
NAHDKLVVMN NTTIVDSPFA FHSILQHDLY AKALTTCIHE RILIDVERHR
160 170 180 190 200
ENVSANNKKR ELNLTIGDIG PLFFIDKAAL KFIENTSKTS KLYPPIDFLY
210 220 230 240 250
NTYDYEQAHP EENNDKISIN ILLEELSKYF LNKNEVDGLI VDFYKTIYPV
260 270 280 290 300
YPLLEISLFE DNIRELLQLN EFNGYNIVFA GKDSRRKLET ITLLTIILAF
310 320 330 340 350
SYRRLSLSTS HSFKESFGVK SNNLTLLAHK LLALMNVFQY VNEHTLCCLL
360 370 380 390 400
YFFILRYLNP DQADMYPTHS DILNLKFLEN VAIKLGLNEE PFQYTRYVSE
410 420 430 440 450
SDDYPRLFNL RRKLWLGVQF LKFGILIPEG DSDILSLEYL RSFMKTDESL
460 470 480 490 500
PELFERNYAS TNNLDLSLMA TAENIYHLHL SLQVLLTSCF PINGPSYLKE
510 520 530 540 550
VLDNIDKTKD FLNQKFPLIL SSLGEPRMKS LHINVPSSLA NEESFDFSTF
560 570 580 590 600
EENETFIANV ISYTCTMNIY DSLSLHFENQ CFKNALEYKT YYHRFTFTAI
610 620 630 640 650
QDYLTLLKLI SEYFNGSLLH LREPFGFATQ KVVRFSIHRL LIFQATLLVR
660 670 680 690 700
LFYKKDTCDR SSAAMGMLND RNGRLSRVIE KMIKLMSYHM KLLVEIVISK
710 720 730 740 750
LEKSYLGSFI SVSIFRYIIY LVDTDALSAF ISDYWKSDAV MDERYSRIHR
760 770 780 790 800
IVGLKWGMGR DKSFSFTSKL NNPQFLGSLD LEILEELEKL ISAQEFSRNF
810 820 830 840
TEDVDESLQS EIDLMNYDNE ALNQLMAIDL DKLLGIFPNL SNF
Length:843
Mass (Da):97,610
Last modified:September 21, 2011 - v2
Checksum:iF03F8237481BE260
GO

Sequence cautioni

The sequence AAT92638.1 differs from that shown. Reason: Frameshift at position 768. Curated
The sequence CAA88003.1 differs from that shown. Reason: Frameshift at position 768. Curated
The sequence CAA97507.1 differs from that shown. Reason: Frameshift at position 768. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z47973 Genomic DNA. Translation: CAA88003.1. Frameshift.
Z73159 Genomic DNA. Translation: CAA97507.1. Frameshift.
AY692619 Genomic DNA. Translation: AAT92638.1. Frameshift.
BK006945 Genomic DNA. Translation: DAA09270.2.
PIRiS50966.
RefSeqiNP_013046.2. NM_001181874.2.

Genome annotation databases

EnsemblFungiiYLL054C; YLL054C; YLL054C.
GeneIDi850672.
KEGGisce:YLL054C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z47973 Genomic DNA. Translation: CAA88003.1. Frameshift.
Z73159 Genomic DNA. Translation: CAA97507.1. Frameshift.
AY692619 Genomic DNA. Translation: AAT92638.1. Frameshift.
BK006945 Genomic DNA. Translation: DAA09270.2.
PIRiS50966.
RefSeqiNP_013046.2. NM_001181874.2.

3D structure databases

ProteinModelPortaliQ12244.
SMRiQ12244. Positions 12-50.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31261. 17 interactions.
DIPiDIP-5612N.
IntActiQ12244. 1 interaction.
MINTiMINT-480719.

PTM databases

iPTMnetiQ12244.

Proteomic databases

MaxQBiQ12244.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYLL054C; YLL054C; YLL054C.
GeneIDi850672.
KEGGisce:YLL054C.

Organism-specific databases

EuPathDBiFungiDB:YLL054C.
SGDiS000003977. YLL054C.

Phylogenomic databases

GeneTreeiENSGT00390000000033.
InParanoidiQ12244.
OMAiCIHERIL.
OrthoDBiEOG7673K6.

Enzyme and pathway databases

BioCyciYEAST:G3O-32153-MONOMER.

Miscellaneous databases

NextBioi966659.
PROiQ12244.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII."
    Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H.
    , Hilger F., Kleine K., Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., Hani J., Hoheisel J.D.
    Nature 387:87-90(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION, SEQUENCE REVISION TO 768.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. "Phenotypic analysis of genes encoding yeast zinc cluster proteins."
    Akache B., Wu K., Turcotte B.
    Nucleic Acids Res. 29:2181-2190(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
    Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
    J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Strain: ADR376.
  7. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
    Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
    Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiYL054_YEAST
AccessioniPrimary (citable) accession number: Q12244
Secondary accession number(s): D6VXV4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: September 21, 2011
Last modified: May 11, 2016
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 339 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XII
    Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.