Q12239 (YO107_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized membrane protein YOL107W

Gene names

Ordered Locus Names:

YOL107W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	342 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Golgi apparatus membrane; Multi-pass membrane protein Ref.4.
Miscellaneous	Present with 1630 molecules/cell in log phase SD medium.

Ontologies

Keywords
Cellular component	Golgi apparatus Membrane
Domain	Transmembrane Transmembrane helix
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	Golgi apparatus Inferred from direct assay Ref.4. Source: SGD Golgi membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 342	342	Uncharacterized membrane protein YOL107W		PRO_0000235931
Regions
	Topological domain	1 – 21	21	Cytoplasmic Potential
	Transmembrane	22 – 42	21	Helical; Potential
	Topological domain	43 – 121	79	Lumenal Potential
	Transmembrane	122 – 142	21	Helical; Potential
	Topological domain	143 – 159	17	Cytoplasmic Potential
	Transmembrane	160 – 180	21	Helical; Potential
	Topological domain	181 – 207	27	Lumenal Potential
	Transmembrane	208 – 228	21	Helical; Potential
	Topological domain	229 – 342	114	Cytoplasmic Potential
Amino acid modifications
	Glycosylation	114	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	Q12239 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 75C352C4CE35DC57	FASTA	342	39,742
	10 20 30 40 50 60 MQYSSRFLEL NIPDSFLNIN KIPDATKFIT VTYICLTATL FCIRRSLYNK LVLEDPNLDY 70 80 90 100 110 120 NLITSPLLQM VPSQIWRYPT SLVLSNFIDT KAWKVVVNLL NLIIGGSFIE RNWNSSKEMF 130 140 150 160 170 180 KFIIVLGSLT NVLIIMLTLL VSFFSNKVRL DIPLDGNYTI LIGFPIIYRQ LLPETTIIHL 190 200 210 220 230 240 KTPQFLAKNF RFKLLPIFVM FTMTVTQIIW FHHFAQLFSI WVTFFASWSY LRFFQKLAPL 250 260 270 280 290 300 NCPSLPTTNS QGGQEILVGD ASDTFQLIYF FPDLIKPILR PIFNFIYNVV VVKFKVIKPF 310 320 330 340 HDIDIDIGNT IAESRGAKKI MTVEERRRQL ALQVLEERMV NP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of a 44 kb DNA fragment of yeast chromosome XV including the Ty1-H3 retrotransposon, the suf1(+) frameshift suppressor gene for tRNA-Gly, the yeast transfer RNA-Thr-1a and a delta element." Vandenbol M., Durand P., Portetelle D., Hilger F. Yeast 11:1069-1075(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[2]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XV." Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D. , de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K. Nature 387:98-102(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[3]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[4]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]	"A global topology map of the Saccharomyces cerevisiae membrane proteome." Kim H., Melen K., Oesterberg M., von Heijne G. Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract] Cited for: TOPOLOGY [LARGE SCALE ANALYSIS]. Strain: ATCC 208353 / W303-1A.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z48149 Genomic DNA. Translation: CAA88154.1. Z74849 Genomic DNA. Translation: CAA99126.1. BK006948 Genomic DNA. Translation: DAA10676.1.
PIR	S51891.
RefSeq	NP_014534.1. NM_001183361.1.
3D structure databases
ProteinModelPortal	Q12239.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-4218N.
IntAct	Q12239. 1 interaction.
MINT	MINT-554964.
STRING	4932.YOL107W.
Proteomic databases
PaxDb	Q12239.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YOL107W; YOL107W; YOL107W.
GeneID	854043.
KEGG	sce:YOL107W.
Organism-specific databases
CYGD	YOL107w.
SGD	S000005467. YOL107W.
Phylogenomic databases
eggNOG	NOG251000.
GeneTree	ENSGT00390000002470.
HOGENOM	HOG000065992.
OMA	PEHNIVL.
OrthoDB	EOG4CNV1Q.
Gene expression databases
Genevestigator	Q12239.
GermOnline	YOL107W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR013861. DUF1751_Mem_euk. [Graphical view]
Pfam	PF08551. DUF1751. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	975615.

Entry information

Entry name

YO107_YEAST

Accession

Primary (citable) accession number: Q12239
Secondary accession number(s): D6W1W0

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 16, 2006
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program