Reviewed,
UniProtKB/Swiss-Prot Q12220 (UTP12_YEAST)
Last modified
December 15, 2009.
Version 82.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: U3 small nucleolar RNA-associated protein 12 Short name=U3 snoRNA-associated protein 12 Alternative name(s): U three protein 12 DOM34-interacting protein 2 | ||||||||
| Gene names |
| ||||||||
| Organism | Saccharomyces cerevisiae (Baker's yeast) [Complete proteome] | ||||||||
| Taxonomic identifier | 4932 [NCBI] | ||||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 943 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Involved in nucleolar processing of pre-18S ribosomal RNA. Ref.2 |
| Subunit structure | Interacts with snoRNA U3. Interacts with MPP10. Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Ref.2 |
| Subcellular location | |
| Miscellaneous | Present with 9620 molecules/cell in log phase SD medium. Ref.3 |
| Sequence similarities | Belongs to the WD repeat WDR3/UTP12 family. Contains 10 WD repeats. |
Ontologies
Binary interactions
With | Entry | #Exp. | IntAct | Notes |
|---|---|---|---|---|
| PWP2 | P25635 | 1 | EBI-5896,EBI-14332 | |
| UBP10 | P53874 | 1 | EBI-5896,EBI-19873 |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 943 | 943 | U3 small nucleolar RNA-associated protein 12 | PRO_0000050955 | |||||
Regions | |||||||||
| Repeat | 77 – 107 | 31 | WD 1 | ||||||
| Repeat | 119 – 149 | 31 | WD 2 | ||||||
| Repeat | 161 – 190 | 30 | WD 3 | ||||||
| Repeat | 202 – 230 | 29 | WD 4 | ||||||
| Repeat | 389 – 418 | 30 | WD 5 | ||||||
| Repeat | 428 – 458 | 31 | WD 6 | ||||||
| Repeat | 471 – 501 | 31 | WD 7 | ||||||
| Repeat | 571 – 601 | 31 | WD 8 | ||||||
| Repeat | 613 – 643 | 31 | WD 9 | ||||||
| Repeat | 655 – 685 | 31 | WD 10 | ||||||
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| U53877 Genomic DNA. Translation: AAB82375.1. U53881 Genomic DNA. Translation: AAB82402.1. X91258 Genomic DNA. Translation: CAA62640.1. Z73301 Genomic DNA. Translation: CAA97699.1. Z73302 Genomic DNA. Translation: CAA97700.1. X89514 Genomic DNA. Translation: CAA61707.1. | |
| PIR | S59317. |
| RefSeq | NP_013230.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP-6494N. |
| IntAct | Q12220. 21 interactions. |
| STRING | Q12220. |
Proteomic databases | |
| PeptideAtlas | Q12220. |
Genome annotation databases | |
| Ensembl | YLR129W; YLR129W; YLR129W; Saccharomyces cerevisiae. [Genome view] |
| GeneID | 850820. |
| KEGG | sce:YLR129W. |
| NMPDR | fig|4932.3.peg.4223. |
Organism-specific databases | |
| CYGD | YLR129w. |
| SGD | S000004119. DIP2. |
Phylogenomic databases | |
| HOGENOM | HBG379828. |
| OMA | SSADKNI. |
| OrthoDB | EOG9H73VF. |
Gene expression databases | |
| ArrayExpress | Q12220. |
| Genevestigator | Q12220. |
| GermOnline | YLR129W. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR020472. G-protein_beta_WD-40_rep_reg. IPR007148. SSU_processome_Utp12. IPR015943. WD40/YVTN_repeat-like_dom. IPR001680. WD40_repeat. IPR011046. WD40_repeat-like_dom. IPR019782. WD40_repeat_2. IPR019775. WD40_repeat_CS. IPR017986. WD40_repeat_dom. IPR019781. WD40_repeat_sg. [Graphical view] |
| Gene3D | G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 2 hits. |
| Pfam | PF04003. Utp12. 1 hit. PF00400. WD40. 9 hits. [Graphical view] |
| PRINTS | PR00320. GPROTEINBRPT. |
| SMART | SM00320. WD40. 11 hits. [Graphical view] |
| PROSITE | PS00678. WD_REPEATS_1. 4 hits. PS50082. WD_REPEATS_2. 8 hits. PS50294. WD_REPEATS_REGION. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 967067. |
Entry information
| Entry name | UTP12_YEAST | ||||||||
| Accession | Primary (citable) accession number: Q12220 Secondary accession number(s): Q05386 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |

Clusters with


