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Protein

60S ribosomal protein L7-B

Gene

RPL7B

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • poly(A) RNA binding Source: GO_Central
  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • cytoplasmic translation Source: SGD
  • maturation of LSU-rRNA Source: SGD
  • maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: GO_Central
  • ribosomal large subunit biogenesis Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-34090-MONOMER.
ReactomeiR-SCE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SCE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SCE-72689. Formation of a pool of free 40S subunits.
R-SCE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SCE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SCE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L7-B
Alternative name(s):
L6
RP11
YL8
Gene namesi
Name:RPL7B
Synonyms:RPL6B, YL8B
Ordered Locus Names:YPL198W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPL198W.
SGDiS000006119. RPL7B.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: SGD
  • cytosolic large ribosomal subunit Source: SGD
  • nucleolus Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001046522 – 24460S ribosomal protein L7-BAdd BLAST243

Proteomic databases

MaxQBiQ12213.
PRIDEiQ12213.

PTM databases

iPTMnetiQ12213.

Interactioni

Subunit structurei

Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S).1 Publication

Protein-protein interaction databases

BioGridi35986. 67 interactors.
IntActiQ12213. 108 interactors.
MINTiMINT-8285476.

Structurei

3D structure databases

ProteinModelPortaliQ12213.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L30P family.Curated

Phylogenomic databases

GeneTreeiENSGT00390000006213.
HOGENOMiHOG000170917.
InParanoidiQ12213.
KOiK02937.
OMAiFGNREDN.
OrthoDBiEOG092C4MAX.

Family and domain databases

Gene3Di3.30.1390.20. 2 hits.
InterProiIPR018038. Ribosomal_L30_CS.
IPR016082. Ribosomal_L30_ferredoxin-like.
IPR012988. Ribosomal_L30_N.
IPR005998. Ribosomal_L7_euk.
[Graphical view]
PfamiPF00327. Ribosomal_L30. 1 hit.
PF08079. Ribosomal_L30_N. 1 hit.
[Graphical view]
SUPFAMiSSF55129. SSF55129. 1 hit.
TIGRFAMsiTIGR01310. uL30_euk. 1 hit.
PROSITEiPS00634. RIBOSOMAL_L30. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q12213-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTEKILTPE SQLKKTKAQQ KTAEQIAAER AARKAANKEK RAIILERNAA
60 70 80 90 100
YQKEYETAER NIIQAKRDAK AAGSYYVEAQ HKLVFVVRIK GINKIPPKPR
110 120 130 140 150
KVLQLLRLTR INSGTFVKVT KATLELLKLI EPYVAYGYPS YSTIRQLVYK
160 170 180 190 200
RGFGKINKQR VPLSDNAIIE ANLGKYGILS IDDLIHEIIT VGPHFKQANN
210 220 230 240
FLWPFKLSNP SGGWGVPRKF KHFIQGGSFG NREEFINKLV KAMN
Length:244
Mass (Da):27,696
Last modified:January 23, 2007 - v3
Checksum:i27F8FC0EE61EC266
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D25232 Genomic DNA. Translation: BAA04957.1.
Z73554 Genomic DNA. Translation: CAA97911.1.
BK006949 Genomic DNA. Translation: DAA11237.1.
PIRiS55910.
RefSeqiNP_015126.1. NM_001184012.1.

Genome annotation databases

EnsemblFungiiYPL198W; YPL198W; YPL198W.
GeneIDi855903.
KEGGisce:YPL198W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D25232 Genomic DNA. Translation: BAA04957.1.
Z73554 Genomic DNA. Translation: CAA97911.1.
BK006949 Genomic DNA. Translation: DAA11237.1.
PIRiS55910.
RefSeqiNP_015126.1. NM_001184012.1.

3D structure databases

ProteinModelPortaliQ12213.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35986. 67 interactors.
IntActiQ12213. 108 interactors.
MINTiMINT-8285476.

PTM databases

iPTMnetiQ12213.

Proteomic databases

MaxQBiQ12213.
PRIDEiQ12213.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYPL198W; YPL198W; YPL198W.
GeneIDi855903.
KEGGisce:YPL198W.

Organism-specific databases

EuPathDBiFungiDB:YPL198W.
SGDiS000006119. RPL7B.

Phylogenomic databases

GeneTreeiENSGT00390000006213.
HOGENOMiHOG000170917.
InParanoidiQ12213.
KOiK02937.
OMAiFGNREDN.
OrthoDBiEOG092C4MAX.

Enzyme and pathway databases

BioCyciYEAST:G3O-34090-MONOMER.
ReactomeiR-SCE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SCE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SCE-72689. Formation of a pool of free 40S subunits.
R-SCE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SCE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SCE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiQ12213.

Family and domain databases

Gene3Di3.30.1390.20. 2 hits.
InterProiIPR018038. Ribosomal_L30_CS.
IPR016082. Ribosomal_L30_ferredoxin-like.
IPR012988. Ribosomal_L30_N.
IPR005998. Ribosomal_L7_euk.
[Graphical view]
PfamiPF00327. Ribosomal_L30. 1 hit.
PF08079. Ribosomal_L30_N. 1 hit.
[Graphical view]
SUPFAMiSSF55129. SSF55129. 1 hit.
TIGRFAMsiTIGR01310. uL30_euk. 1 hit.
PROSITEiPS00634. RIBOSOMAL_L30. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL7B_YEAST
AccessioniPrimary (citable) accession number: Q12213
Secondary accession number(s): D6W3H1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 138 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 7080 molecules/cell in log phase SD medium.1 Publication
There are 2 genes for L7 in yeast.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.