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Protein

Halotolerance protein 9

Gene

HAL9

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Putative transcription factor involved in halotolerance.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi136 – 16631Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • positive regulation of transcription from RNA polymerase II promoter Source: SGD
  • response to salt stress Source: SGD
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-33489-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Halotolerance protein 9
Gene namesi
Name:HAL9
Ordered Locus Names:YOL089C
ORF Names:O0938
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOL089C.
SGDiS000005449. HAL9.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: UniProtKB-SubCell
  • nucleus Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10301030Halotolerance protein 9PRO_0000233012Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei221 – 2211PhosphoserineCombined sources
Modified residuei937 – 9371PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ12180.

PTM databases

iPTMnetiQ12180.

Interactioni

Protein-protein interaction databases

BioGridi34313. 63 interactions.
IntActiQ12180. 17 interactions.
MINTiMINT-4501966.

Structurei

3D structure databases

ProteinModelPortaliQ12180.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00700000105830.
InParanoidiQ12180.
OMAiDMLTDQN.
OrthoDBiEOG092C2P2C.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR007219. Transcription_factor_dom_fun.
IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF04082. Fungal_trans. 1 hit.
PF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00906. Fungal_trans. 1 hit.
SM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q12180-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENQGGDYSP NGFSNSASNM NAVFNNEITG RSDISNVNHQ TGTPRLVPET
60 70 80 90 100
QIWSMPVPDQ LMTMPNRENT LMTGSTIGPN IPMNVAYPNT IYSPTEHQSQ
110 120 130 140 150
FQTQQNRDIS TMMEHTNSND MSGSGKNLKK RVSKACDHCR KRKIRCDEVD
160 170 180 190 200
QQTKKCSNCI KFQLPCTFKH RDEILKKKRK LEIKHHATPG ESLQTSNSIS
210 220 230 240 250
NPVASSSVPN SGRFELLNGN SPLESNIIDK VSNIQNNLNK KMNSKIEKLD
260 270 280 290 300
RKMSYIIDSV ARLEWLLDKA VKKQEGKYKE KNNLPKPARK IYSTALLTAQ
310 320 330 340 350
KLYWFKQSLG VKASNEEFLS PISEILSISL KWYATQMKKF MDLSSPAFFS
360 370 380 390 400
SEIILYSLPP KKQAKRLLEN FHATLLSSVT GIISLKECLD LAEKYYSESG
410 420 430 440 450
EKLTYPEHLL LNVCLCSGAS ATQSIIRGDS KFLRKDRYDP TSQELKKIEN
460 470 480 490 500
VALLNAMYYY HKLSTICSGT RTLQALLLLN RYFQLTYDTE LANCILGTAI
510 520 530 540 550
RLAVDMELNR KSSYKSLDFE EAIRRRRMWW HCFCTDKLYS LMLSRPPIVG
560 570 580 590 600
ERDMDMLTDQ NYYEVIKTNI LPDLIDKKED LDKITDVNSA LNVVVNFCQH
610 620 630 640 650
ISLFISYYVS KLVSIESKIY STCFAVRSTL DLSFDAMLDK IKDLNDSLNN
660 670 680 690 700
WRDNLHVSMK LKSYKQYLSV LYAQKSQENP ALSFEIACSR VLNCHFRALY
710 720 730 740 750
SKVILSMMTT SLLIDNERLY KGSRHDIPQL FILFSSQYLN ASKEMLQLFQ
760 770 780 790 800
GINYQAHMYN EVMYQFSTAM FVLFFYVVDN MNDLKKKGEV KEIIDILKKS
810 820 830 840 850
YDRLVGENDE QLLFDNVKWN TLIVFYSHFL KYVLQRYHAL NDSTSIFDSK
860 870 880 890 900
PYDETITKVI MHSRKIKDET VDQLIMSLKS YGSLHSLQKG NEADLADDGL
910 920 930 940 950
NTNDISSEDF AEEAPINLFG ELSVEILKLL KSHSPISNFG DLSPSSNRKG
960 970 980 990 1000
ISDDSSLYPI RSDLTSLVYP IHSSDTGDTL SSGLETPENS NFNSDSGIKE
1010 1020 1030
DFEAFRALLP LGKLIYDRDY SFVNTFRDYE
Length:1,030
Mass (Da):117,927
Last modified:November 1, 1996 - v1
Checksum:i8C8BDE84066D2105
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X83121 Genomic DNA. Translation: CAA58190.1.
Z74831 Genomic DNA. Translation: CAA99101.1.
BK006948 Genomic DNA. Translation: DAA10695.1.
PIRiS57380.
RefSeqiNP_014552.1. NM_001183343.1.

Genome annotation databases

EnsemblFungiiYOL089C; YOL089C; YOL089C.
GeneIDi854064.
KEGGisce:YOL089C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X83121 Genomic DNA. Translation: CAA58190.1.
Z74831 Genomic DNA. Translation: CAA99101.1.
BK006948 Genomic DNA. Translation: DAA10695.1.
PIRiS57380.
RefSeqiNP_014552.1. NM_001183343.1.

3D structure databases

ProteinModelPortaliQ12180.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34313. 63 interactions.
IntActiQ12180. 17 interactions.
MINTiMINT-4501966.

PTM databases

iPTMnetiQ12180.

Proteomic databases

MaxQBiQ12180.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYOL089C; YOL089C; YOL089C.
GeneIDi854064.
KEGGisce:YOL089C.

Organism-specific databases

EuPathDBiFungiDB:YOL089C.
SGDiS000005449. HAL9.

Phylogenomic databases

GeneTreeiENSGT00700000105830.
InParanoidiQ12180.
OMAiDMLTDQN.
OrthoDBiEOG092C2P2C.

Enzyme and pathway databases

BioCyciYEAST:G3O-33489-MONOMER.

Miscellaneous databases

PROiQ12180.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR007219. Transcription_factor_dom_fun.
IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF04082. Fungal_trans. 1 hit.
PF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00906. Fungal_trans. 1 hit.
SM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHAL9_YEAST
AccessioniPrimary (citable) accession number: Q12180
Secondary accession number(s): D6W1X9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 18, 2006
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 238 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.