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Protein

Zinc finger transcription factor YRR1

Gene

YRR1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Transcription factor involved in the regulation of multidrug resistance genes. Acts in concert with YRR1.5 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi54 – 82Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd BLAST29

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-33679-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger transcription factor YRR1
Alternative name(s):
Pleiotropic drug-resistance protein 2
Gene namesi
Name:YRR1
Synonyms:PDR2
Ordered Locus Names:YOR162C
ORF Names:O3571
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOR162C
SGDiS000005688 YRR1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002696511 – 810Zinc finger transcription factor YRR1Add BLAST810

Proteomic databases

MaxQBiQ12172
PaxDbiQ12172
PRIDEiQ12172

PTM databases

iPTMnetiQ12172

Interactioni

Protein-protein interaction databases

BioGridi34558, 37 interactors
DIPiDIP-5493N
IntActiQ12172, 10 interactors
MINTiQ12172
STRINGi4932.YOR162C

Structurei

3D structure databases

ProteinModelPortaliQ12172
SMRiQ12172
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000010685
HOGENOMiHOG000155687
InParanoidiQ12172
OMAiLVNINEC
OrthoDBiEOG092C0IY5

Family and domain databases

CDDicd00067 GAL4, 1 hit
Gene3Di4.10.240.10, 1 hit
InterProiView protein in InterPro
IPR001138 Zn2-C6_fun-type_DNA-bd
IPR036864 Zn2-C6_fun-type_DNA-bd_sf
PfamiView protein in Pfam
PF00172 Zn_clus, 1 hit
SMARTiView protein in SMART
SM00066 GAL4, 1 hit
SUPFAMiSSF57701 SSF57701, 1 hit
PROSITEiView protein in PROSITE
PS00463 ZN2_CY6_FUNGAL_1, 1 hit
PS50048 ZN2_CY6_FUNGAL_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q12172-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRRSDALLG SFQATNVTPP SDNSNSTAGG ANGSNSGTPT STSGKKRNKL
60 70 80 90 100
IKSCGFCRRR KLRCDQQKPM CSTCISRNLT TCQYAEEFNK NIEKKATYGP
110 120 130 140 150
YPNADLLKKV EELENKIRIL EAEKNTNSSA SSMYTSPNFP PLGTSVGRGS
160 170 180 190 200
TETSSPLPDG VINPYADRYY LQSKHSGRST LYGPTSMRTQ IANSNWGFIE
210 220 230 240 250
KYKQLWAKVK VERNKWKQNN QKTMCRELGL LDESDWQPDP LIKQICRFLP
260 270 280 290 300
SYNKALSILD DFFNDGACNE INVILDKAKV RRDFLDYFMP EKEVKAEGDR
310 320 330 340 350
SIVYILSNPK KNYYKAAVIL LILCLKYFHT DVPTPIEKFF TLLKGASTAK
360 370 380 390 400
VFYIERAQML ILFYYHRETY SFGGDGSDLV NINECLVTTV TTIGLHLNIR
410 420 430 440 450
ETFKEHEVFM GSIESLENVW LMAIFIDYNI SCNVGRPLLI NKFYLDENQD
460 470 480 490 500
HCILNSKSKT YEGKLKRYLK LTRPMLLTLY DRDKFPDLKA YSKRIINFVE
510 520 530 540 550
EELGPLGHYT GENISEEVPL RESRILSMAV GLLLSFYALI HSVLKVRNIE
560 570 580 590 600
SKNNTFQLVL INFSIIVNTT IRCYRIDKAL YPEKFEASNP HLPPHMALSM
610 620 630 640 650
SLTAGLFSKT LVFFCSLIYF KLTLFENGLC LSNDMEVGWS DLTKLTVPLD
660 670 680 690 700
KDLSLGTAMS LYSSIFDRLF TVGNKELIRT MHRSSQFVIE LAIERTYRTI
710 720 730 740 750
LGNVIEFRKL TEETWLAQIK QELDPQSDNP SSEAKIVSDR QRDLSLAVPT
760 770 780 790 800
PTPSIIPMLP SPGETKNHAK SQSEIIQMLT DEFWANYNSG WEELINQSEF
810
STLFDDYKDN
Length:810
Mass (Da):92,468
Last modified:November 1, 1996 - v1
Checksum:i1B4A32A91CFF2515
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U55021 Genomic DNA Translation: AAB47409.1
Z75070 Genomic DNA Translation: CAA99368.1
AY692760 Genomic DNA Translation: AAT92779.1
BK006948 Genomic DNA Translation: DAA10936.1
PIRiS67050
RefSeqiNP_014805.3, NM_001183581.3

Genome annotation databases

EnsemblFungiiYOR162C; YOR162C; YOR162C
GeneIDi854333
KEGGisce:YOR162C

Similar proteinsi

Entry informationi

Entry nameiYRR1_YEAST
AccessioniPrimary (citable) accession number: Q12172
Secondary accession number(s): D6W2M0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health