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Protein

Ribosome biogenesis protein SSF2

Gene

SSF2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required for biogenesis of the 60S ribosomal subunit.1 Publication

Miscellaneous

Present with 1350 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • rRNA binding Source: SGD

GO - Biological processi

  • conjugation with cellular fusion Source: SGD
  • ribosomal large subunit assembly Source: SGD

Keywordsi

Biological processRibosome biogenesis

Enzyme and pathway databases

BioCyciYEAST:G3O-29871-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosome biogenesis protein SSF2
Gene namesi
Name:SSF2
Ordered Locus Names:YDR312W
ORF Names:D9740.2
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR312W
SGDiS000002720 SSF2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001202601 – 453Ribosome biogenesis protein SSF2Add BLAST453

Proteomic databases

MaxQBiQ12153
PaxDbiQ12153
PRIDEiQ12153

PTM databases

iPTMnetiQ12153

Interactioni

Subunit structurei

Part of a complex that includes BRX1, RPF1, RPF2 and SSF1 or SSF2.

Binary interactionsi

WithEntry#Exp.IntActNotes
RRP15Q065115EBI-18168,EBI-34602

Protein-protein interaction databases

BioGridi32365, 98 interactors
DIPiDIP-6502N
IntActiQ12153, 15 interactors
MINTiQ12153
STRINGi4932.YDR312W

Structurei

3D structure databases

ProteinModelPortaliQ12153
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 348BrixPROSITE-ProRule annotationAdd BLAST323

Phylogenomic databases

GeneTreeiENSGT00530000064158
HOGENOMiHOG000210038
InParanoidiQ12153
KOiK14859
OMAiWMKENTE
OrthoDBiEOG092C3Q2K

Family and domain databases

InterProiView protein in InterPro
IPR007109 Brix
PfamiView protein in Pfam
PF04427 Brix, 1 hit
SMARTiView protein in SMART
SM00879 Brix, 1 hit
PROSITEiView protein in PROSITE
PS50833 BRIX, 1 hit

Sequencei

Sequence statusi: Complete.

Q12153-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKRRQKKRT HAQITPEQER DIPKSMVIRV GQTSLANHSL NQLVKDFRQI
60 70 80 90 100
MQPHTAVKLK ERKSNKLKDF VVMCGPLGVT HLFMFTQSEK TGNVSLKIAR
110 120 130 140 150
TPQGPTVTFQ VLDYSLGRDI KKFLKRPKSL NNDDVLNPPL LVLNGFSTSK
160 170 180 190 200
RSDEDDQDVN VEKVIVSMFQ NIFPPLNPAR TSLNSIKRIF MINKDRETGE
210 220 230 240 250
ISMRHYFIDI REVEISRNLK RLYKAKNNLS KTVPNLHRKE DISSLILDHD
260 270 280 290 300
LGAYTSESEI EDDAIVRVVD NQDVKAKHSQ TSLSQKTPVK MTDNEEREKG
310 320 330 340 350
IEEEDVEMEE PKPSENSQPT PRKKAIKLTE LGPRLTLKLV KIEDGICSGK
360 370 380 390 400
VLHHEFVQKS SEEIKALEKR HAAKMRLKEQ RRKEQEENIA KKKAVKDAKK
410 420 430 440 450
QRKLERRKAR AEEQGEGQGK DGAMSDDGSS SSEDEHYSDV PEDLDSDLFS

EVE
Length:453
Mass (Da):51,856
Last modified:November 1, 1996 - v1
Checksum:i83306767C4F58816
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18114 Genomic DNA Translation: AAA79981.1
U28374 Genomic DNA Translation: AAB64748.1
BK006938 Genomic DNA Translation: DAA12151.1
PIRiS50248
RefSeqiNP_010598.3, NM_001180620.3

Genome annotation databases

EnsemblFungiiYDR312W; YDR312W; YDR312W
GeneIDi851907
KEGGisce:YDR312W

Similar proteinsi

Entry informationi

Entry nameiSSF2_YEAST
AccessioniPrimary (citable) accession number: Q12153
Secondary accession number(s): D6VSU1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names
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