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Q12144

- PER33_YEAST

UniProt

Q12144 - PER33_YEAST

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Protein

Pore and endoplasmic reticulum protein of 33 kDa

Gene

PER33

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. mRNA transport Source: UniProtKB-KW
  2. protein transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

mRNA transport, Protein transport, Translocation, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-32217-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Pore and endoplasmic reticulum protein of 33 kDa
Gene namesi
Name:PER33
Ordered Locus Names:YLR064W
ORF Names:L2177
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XII

Organism-specific databases

CYGDiYLR064w.
SGDiS000004054. PER33.

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: SGD
  2. nuclear pore Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane, Nuclear pore complex, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 273273Pore and endoplasmic reticulum protein of 33 kDaPRO_0000247231Add
BLAST

Proteomic databases

MaxQBiQ12144.
PaxDbiQ12144.

Expressioni

Gene expression databases

GenevestigatoriQ12144.

Interactioni

Protein-protein interaction databases

BioGridi31338. 37 interactions.
DIPiDIP-4778N.
IntActiQ12144. 3 interactions.
MINTiMINT-516871.
STRINGi4932.YLR064W.

Structurei

3D structure databases

ProteinModelPortaliQ12144.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2424CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini46 – 5611LumenalSequence AnalysisAdd
BLAST
Topological domaini75 – 9824CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini120 – 1267LumenalSequence Analysis
Topological domaini148 – 17629CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini198 – 1992LumenalSequence Analysis
Topological domaini221 – 27353CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei25 – 4521HelicalSequence AnalysisAdd
BLAST
Transmembranei57 – 7418HelicalSequence AnalysisAdd
BLAST
Transmembranei99 – 11921HelicalSequence AnalysisAdd
BLAST
Transmembranei127 – 14721HelicalSequence AnalysisAdd
BLAST
Transmembranei177 – 19721HelicalSequence AnalysisAdd
BLAST
Transmembranei200 – 22021HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the PER33/POM33 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG264936.
InParanoidiQ12144.
OMAiIVHIAWI.
OrthoDBiEOG7WX0N1.

Sequencei

Sequence statusi: Complete.

Q12144-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTVPRNRPMA PFGTIIKSRI KQPQFYWFIG HFLTIFNFIQ FHLSITSKQN
60 70 80 90 100
QLSCYRRSLF YISVTYAIVL YQFFKSDQLK FNFTLLRQEM KKLDNLQYFA
110 120 130 140 150
MLFILFLLSQ FNIIISGSLY SPVIFSIFHF LNYFKENLLP FLPLIPLNLK
160 170 180 190 200
NLLNSKITVF IQNYNGFFLQ MAQVFEIICG LRVGLFLVPF NFFLLLVRRA
210 220 230 240 250
NVSFEVVGTM LAGLTYVWFF KLRYLQSESM RQIFKQYVLR LDAYVSRTLP
260 270
PYCSRLWNGY KNFVMTVFWK IPV
Length:273
Mass (Da):32,637
Last modified:November 1, 1996 - v1
Checksum:iF6B7E3A3D1D74F38
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X94607 Genomic DNA. Translation: CAA64310.1.
Z73236 Genomic DNA. Translation: CAA97620.1.
AY692677 Genomic DNA. Translation: AAT92696.1.
BK006945 Genomic DNA. Translation: DAA09381.1.
PIRiS61637.
RefSeqiNP_013165.1. NM_001181951.1.

Genome annotation databases

EnsemblFungiiYLR064W; YLR064W; YLR064W.
GeneIDi850753.
KEGGisce:YLR064W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X94607 Genomic DNA. Translation: CAA64310.1 .
Z73236 Genomic DNA. Translation: CAA97620.1 .
AY692677 Genomic DNA. Translation: AAT92696.1 .
BK006945 Genomic DNA. Translation: DAA09381.1 .
PIRi S61637.
RefSeqi NP_013165.1. NM_001181951.1.

3D structure databases

ProteinModelPortali Q12144.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 31338. 37 interactions.
DIPi DIP-4778N.
IntActi Q12144. 3 interactions.
MINTi MINT-516871.
STRINGi 4932.YLR064W.

Proteomic databases

MaxQBi Q12144.
PaxDbi Q12144.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YLR064W ; YLR064W ; YLR064W .
GeneIDi 850753.
KEGGi sce:YLR064W.

Organism-specific databases

CYGDi YLR064w.
SGDi S000004054. PER33.

Phylogenomic databases

eggNOGi NOG264936.
InParanoidi Q12144.
OMAi IVHIAWI.
OrthoDBi EOG7WX0N1.

Enzyme and pathway databases

BioCyci YEAST:G3O-32217-MONOMER.

Miscellaneous databases

NextBioi 966888.

Gene expression databases

Genevestigatori Q12144.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII."
    Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H.
    , Hilger F., Kleine K., Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., Hani J., Hoheisel J.D.
    Nature 387:87-90(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.
  7. "Pom33, a novel transmembrane nucleoporin required for proper nuclear pore complex distribution."
    Chadrin A., Hess B., San Roman M., Gatti X., Lombard B., Loew D., Barral Y., Palancade B., Doye V.
    J. Cell Biol. 189:795-811(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.

Entry informationi

Entry nameiPER33_YEAST
AccessioniPrimary (citable) accession number: Q12144
Secondary accession number(s): D6VY65
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 2240 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XII
    Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

External Data

Dasty 3