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Q12144

- PER33_YEAST

UniProt

Q12144 - PER33_YEAST

Protein

Pore and endoplasmic reticulum protein of 33 kDa

Gene

PER33

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. mRNA transport Source: UniProtKB-KW
    2. protein transport Source: UniProtKB-KW

    Keywords - Biological processi

    mRNA transport, Protein transport, Translocation, Transport

    Enzyme and pathway databases

    BioCyciYEAST:G3O-32217-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pore and endoplasmic reticulum protein of 33 kDa
    Gene namesi
    Name:PER33
    Ordered Locus Names:YLR064W
    ORF Names:L2177
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XII

    Organism-specific databases

    CYGDiYLR064w.
    SGDiS000004054. PER33.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum Source: SGD
    2. endoplasmic reticulum membrane Source: UniProtKB-SubCell
    3. nuclear pore Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Endoplasmic reticulum, Membrane, Nuclear pore complex, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 273273Pore and endoplasmic reticulum protein of 33 kDaPRO_0000247231Add
    BLAST

    Proteomic databases

    MaxQBiQ12144.
    PaxDbiQ12144.

    Expressioni

    Gene expression databases

    GenevestigatoriQ12144.

    Interactioni

    Protein-protein interaction databases

    BioGridi31338. 37 interactions.
    DIPiDIP-4778N.
    IntActiQ12144. 3 interactions.
    MINTiMINT-516871.
    STRINGi4932.YLR064W.

    Structurei

    3D structure databases

    ProteinModelPortaliQ12144.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 2424CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini46 – 5611LumenalSequence AnalysisAdd
    BLAST
    Topological domaini75 – 9824CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini120 – 1267LumenalSequence Analysis
    Topological domaini148 – 17629CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini198 – 1992LumenalSequence Analysis
    Topological domaini221 – 27353CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei25 – 4521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei57 – 7418HelicalSequence AnalysisAdd
    BLAST
    Transmembranei99 – 11921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei127 – 14721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei177 – 19721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei200 – 22021HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PER33/POM33 family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG264936.
    OMAiIVHIAWI.
    OrthoDBiEOG7WX0N1.

    Sequencei

    Sequence statusi: Complete.

    Q12144-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTVPRNRPMA PFGTIIKSRI KQPQFYWFIG HFLTIFNFIQ FHLSITSKQN    50
    QLSCYRRSLF YISVTYAIVL YQFFKSDQLK FNFTLLRQEM KKLDNLQYFA 100
    MLFILFLLSQ FNIIISGSLY SPVIFSIFHF LNYFKENLLP FLPLIPLNLK 150
    NLLNSKITVF IQNYNGFFLQ MAQVFEIICG LRVGLFLVPF NFFLLLVRRA 200
    NVSFEVVGTM LAGLTYVWFF KLRYLQSESM RQIFKQYVLR LDAYVSRTLP 250
    PYCSRLWNGY KNFVMTVFWK IPV 273
    Length:273
    Mass (Da):32,637
    Last modified:November 1, 1996 - v1
    Checksum:iF6B7E3A3D1D74F38
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X94607 Genomic DNA. Translation: CAA64310.1.
    Z73236 Genomic DNA. Translation: CAA97620.1.
    AY692677 Genomic DNA. Translation: AAT92696.1.
    BK006945 Genomic DNA. Translation: DAA09381.1.
    PIRiS61637.
    RefSeqiNP_013165.1. NM_001181951.1.

    Genome annotation databases

    EnsemblFungiiYLR064W; YLR064W; YLR064W.
    GeneIDi850753.
    KEGGisce:YLR064W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X94607 Genomic DNA. Translation: CAA64310.1 .
    Z73236 Genomic DNA. Translation: CAA97620.1 .
    AY692677 Genomic DNA. Translation: AAT92696.1 .
    BK006945 Genomic DNA. Translation: DAA09381.1 .
    PIRi S61637.
    RefSeqi NP_013165.1. NM_001181951.1.

    3D structure databases

    ProteinModelPortali Q12144.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 31338. 37 interactions.
    DIPi DIP-4778N.
    IntActi Q12144. 3 interactions.
    MINTi MINT-516871.
    STRINGi 4932.YLR064W.

    Proteomic databases

    MaxQBi Q12144.
    PaxDbi Q12144.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YLR064W ; YLR064W ; YLR064W .
    GeneIDi 850753.
    KEGGi sce:YLR064W.

    Organism-specific databases

    CYGDi YLR064w.
    SGDi S000004054. PER33.

    Phylogenomic databases

    eggNOGi NOG264936.
    OMAi IVHIAWI.
    OrthoDBi EOG7WX0N1.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-32217-MONOMER.

    Miscellaneous databases

    NextBioi 966888.

    Gene expression databases

    Genevestigatori Q12144.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII."
      Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H.
      , Hilger F., Kleine K., Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., Hani J., Hoheisel J.D.
      Nature 387:87-90(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    6. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
      Kim H., Melen K., Oesterberg M., von Heijne G.
      Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
      Strain: ATCC 208353 / W303-1A.
    7. "Pom33, a novel transmembrane nucleoporin required for proper nuclear pore complex distribution."
      Chadrin A., Hess B., San Roman M., Gatti X., Lombard B., Loew D., Barral Y., Palancade B., Doye V.
      J. Cell Biol. 189:795-811(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION.

    Entry informationi

    Entry nameiPER33_YEAST
    AccessioniPrimary (citable) accession number: Q12144
    Secondary accession number(s): D6VY65
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 25, 2006
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 2240 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome XII
      Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

    External Data

    Dasty 3