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Protein

Pore and endoplasmic reticulum protein of 33 kDa

Gene

PER33

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

mRNA transport, Protein transport, Translocation, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-32217-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Pore and endoplasmic reticulum protein of 33 kDa
Gene namesi
Name:PER33
Ordered Locus Names:YLR064W
ORF Names:L2177
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XII

Organism-specific databases

EuPathDBiFungiDB:YLR064W.
SGDiS000004054. PER33.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 24CytoplasmicSequence analysisAdd BLAST24
Transmembranei25 – 45HelicalSequence analysisAdd BLAST21
Topological domaini46 – 56LumenalSequence analysisAdd BLAST11
Transmembranei57 – 74HelicalSequence analysisAdd BLAST18
Topological domaini75 – 98CytoplasmicSequence analysisAdd BLAST24
Transmembranei99 – 119HelicalSequence analysisAdd BLAST21
Topological domaini120 – 126LumenalSequence analysis7
Transmembranei127 – 147HelicalSequence analysisAdd BLAST21
Topological domaini148 – 176CytoplasmicSequence analysisAdd BLAST29
Transmembranei177 – 197HelicalSequence analysisAdd BLAST21
Topological domaini198 – 199LumenalSequence analysis2
Transmembranei200 – 220HelicalSequence analysisAdd BLAST21
Topological domaini221 – 273CytoplasmicSequence analysisAdd BLAST53

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane, Nuclear pore complex, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002472311 – 273Pore and endoplasmic reticulum protein of 33 kDaAdd BLAST273

Proteomic databases

MaxQBiQ12144.
PRIDEiQ12144.

Interactioni

Protein-protein interaction databases

BioGridi31338. 38 interactors.
DIPiDIP-4778N.
IntActiQ12144. 3 interactors.
MINTiMINT-516871.

Structurei

3D structure databases

ProteinModelPortaliQ12144.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PER33/POM33 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ12144.
KOiK20724.
OMAiQQFYWFL.
OrthoDBiEOG092C5IRK.

Family and domain databases

InterProiIPR005344. Per33/Pom33.
[Graphical view]
PfamiPF03661. UPF0121. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q12144-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVPRNRPMA PFGTIIKSRI KQPQFYWFIG HFLTIFNFIQ FHLSITSKQN
60 70 80 90 100
QLSCYRRSLF YISVTYAIVL YQFFKSDQLK FNFTLLRQEM KKLDNLQYFA
110 120 130 140 150
MLFILFLLSQ FNIIISGSLY SPVIFSIFHF LNYFKENLLP FLPLIPLNLK
160 170 180 190 200
NLLNSKITVF IQNYNGFFLQ MAQVFEIICG LRVGLFLVPF NFFLLLVRRA
210 220 230 240 250
NVSFEVVGTM LAGLTYVWFF KLRYLQSESM RQIFKQYVLR LDAYVSRTLP
260 270
PYCSRLWNGY KNFVMTVFWK IPV
Length:273
Mass (Da):32,637
Last modified:November 1, 1996 - v1
Checksum:iF6B7E3A3D1D74F38
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X94607 Genomic DNA. Translation: CAA64310.1.
Z73236 Genomic DNA. Translation: CAA97620.1.
AY692677 Genomic DNA. Translation: AAT92696.1.
BK006945 Genomic DNA. Translation: DAA09381.1.
PIRiS61637.
RefSeqiNP_013165.1. NM_001181951.1.

Genome annotation databases

EnsemblFungiiYLR064W; YLR064W; YLR064W.
GeneIDi850753.
KEGGisce:YLR064W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X94607 Genomic DNA. Translation: CAA64310.1.
Z73236 Genomic DNA. Translation: CAA97620.1.
AY692677 Genomic DNA. Translation: AAT92696.1.
BK006945 Genomic DNA. Translation: DAA09381.1.
PIRiS61637.
RefSeqiNP_013165.1. NM_001181951.1.

3D structure databases

ProteinModelPortaliQ12144.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31338. 38 interactors.
DIPiDIP-4778N.
IntActiQ12144. 3 interactors.
MINTiMINT-516871.

Proteomic databases

MaxQBiQ12144.
PRIDEiQ12144.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYLR064W; YLR064W; YLR064W.
GeneIDi850753.
KEGGisce:YLR064W.

Organism-specific databases

EuPathDBiFungiDB:YLR064W.
SGDiS000004054. PER33.

Phylogenomic databases

InParanoidiQ12144.
KOiK20724.
OMAiQQFYWFL.
OrthoDBiEOG092C5IRK.

Enzyme and pathway databases

BioCyciYEAST:G3O-32217-MONOMER.

Miscellaneous databases

PROiQ12144.

Family and domain databases

InterProiIPR005344. Per33/Pom33.
[Graphical view]
PfamiPF03661. UPF0121. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPER33_YEAST
AccessioniPrimary (citable) accession number: Q12144
Secondary accession number(s): D6VY65
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 2240 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XII
    Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.