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Q12134 (HUA2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein HUA2
Gene names
Name:HUA2
Ordered Locus Names:YOR284W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length243 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May have a role in actin patch assembly. Ref.6

Subcellular location

Cytoplasm Ref.4.

Miscellaneous

Present with 1360 molecules/cell in log phase SD medium.

Ontologies

Keywords
   Cellular componentCytoplasm
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

ABP1P158913EBI-37262,EBI-2036

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 243243Protein HUA2
PRO_0000270558

Sequences

Sequence LengthMass (Da)Tools
Q12134 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: B1F3A81B7C0F65AC

FASTA24328,414
        10         20         30         40         50         60 
MQQTKFGKMY LDHDSVVEYS EDEIVEADRI TLGYKKRLSM IENQMRHLLE DFSLDVQQIE 

        70         80         90        100        110        120 
PILADLQKYY DAFLQLLQKR NKSLQCKRST HQPVPSPMNS QTSTNAKVNL SGKLMKFQLN 

       130        140        150        160        170        180 
SVQKFDEENI LRILQNKIEF EHYFQIDKGK KQKVLLLAVY QCLNGPTRLH KVLNIEGIIH 

       190        200        210        220        230        240 
NNSIRTILGK QVSSSKWTVF LYDVKLVLLA HRQDVPNLET SKMIVRYGDL FPCALYFKDH 


TAY 

« Hide

References

« Hide 'large scale' references
[1]"DNA sequence analysis of the VPH1-SNF2 region on chromosome XV of Saccharomyces cerevisiae."
Cheret G., Bernardi A., Sor F.J.
Yeast 12:1059-1064(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XV."
Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D. expand/collapse author list , de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.
Nature 387:98-102(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[6]"Predicting protein functions from redundancies in large-scale protein interaction networks."
Samanta M.P., Liang S.
Proc. Natl. Acad. Sci. U.S.A. 100:12579-12583(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X89633 Genomic DNA. Translation: CAA61788.1.
Z75192 Genomic DNA. Translation: CAA99511.1.
BK006948 Genomic DNA. Translation: DAA11048.1.
PIRS67186.
RefSeqNP_014927.3. NM_001183703.3.

3D structure databases

ProteinModelPortalQ12134.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid34671. 41 interactions.
DIPDIP-1472N.
IntActQ12134. 24 interactions.
MINTMINT-388764.
STRING4932.YOR284W.

Proteomic databases

PaxDbQ12134.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYOR284W; YOR284W; YOR284W.
GeneID854458.
KEGGsce:YOR284W.

Organism-specific databases

CYGDYOR284w.
SGDS000005810. HUA2.

Phylogenomic databases

OrthoDBEOG718KPR.

Enzyme and pathway databases

BioCycYEAST:G3O-33770-MONOMER.

Gene expression databases

GenevestigatorQ12134.

Family and domain databases

ProtoNetSearch...

Other

NextBio976730.

Entry information

Entry nameHUA2_YEAST
AccessionPrimary (citable) accession number: Q12134
Secondary accession number(s): D6W2Y2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: November 1, 1996
Last modified: February 19, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XV

Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD