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Q12119

- FCY22_YEAST

UniProt

Q12119 - FCY22_YEAST

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Protein

Purine-cytosine permease FCY22

Gene

FCY22

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Probable purine-cytosine permease.By similarity

GO - Molecular functioni

  1. nucleobase transmembrane transporter activity Source: SGD

GO - Biological processi

  1. cytosine transport Source: SGD
  2. purine-containing compound transmembrane transport Source: SGD
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-30354-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Purine-cytosine permease FCY22
Short name:
PCP FCY22
Alternative name(s):
Cytosine/purine transport protein FCY22
Fluorocytosine resistance protein 22
Gene namesi
Name:FCY22
Synonyms:FCYX
Ordered Locus Names:YER060W-A
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome V

Organism-specific databases

CYGDiYER060w-a.
SGDiS000002958. FCY22.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 530530Purine-cytosine permease FCY22PRO_0000197922Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriQ12119.

Interactioni

Protein-protein interaction databases

BioGridi36802. 14 interactions.
DIPiDIP-8900N.
STRINGi4932.YER060W-A.

Structurei

3D structure databases

ProteinModelPortaliQ12119.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei96 – 11621HelicalSequence AnalysisAdd
BLAST
Transmembranei119 – 13921HelicalSequence AnalysisAdd
BLAST
Transmembranei162 – 18221HelicalSequence AnalysisAdd
BLAST
Transmembranei197 – 21721HelicalSequence AnalysisAdd
BLAST
Transmembranei220 – 24021HelicalSequence AnalysisAdd
BLAST
Transmembranei263 – 28321HelicalSequence AnalysisAdd
BLAST
Transmembranei298 – 31821HelicalSequence AnalysisAdd
BLAST
Transmembranei345 – 36521HelicalSequence AnalysisAdd
BLAST
Transmembranei372 – 39221HelicalSequence AnalysisAdd
BLAST
Transmembranei396 – 41621HelicalSequence AnalysisAdd
BLAST
Transmembranei418 – 43821HelicalSequence AnalysisAdd
BLAST
Transmembranei463 – 48321HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the purine-cytosine permease family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1457.
GeneTreeiENSGT00390000004423.
HOGENOMiHOG000162981.
InParanoidiQ12119.
OrthoDBiEOG75QRD0.

Family and domain databases

InterProiIPR001248. Cyt_pur_permease.
IPR012681. NCS1.
IPR026030. Pur-cyt_permease.
[Graphical view]
PfamiPF02133. Transp_cyt_pur. 1 hit.
[Graphical view]
PIRSFiPIRSF002744. Pur-cyt_permease. 1 hit.
TIGRFAMsiTIGR00800. ncs1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q12119 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPEKLAMSMV DIKDAGSELR DLESGALDTK SSAADVYYEG VELHRTNEFI
60 70 80 90 100
DNKPSFFNRI AAALNAETKG IEPVTEDEKN DDSILNAATI WFSANMVIVA
110 120 130 140 150
YSVGALGPLV FGLNFGQSVL VIIFFNILGL IPVALFSLFG VELGLRQMIL
160 170 180 190 200
SRYLAGNITA RFFSLVNVIA CVGWCVLNIS VSAQLLNMVN EGSGHNCPIW
210 220 230 240 250
AGCLIIAGGT VLVTFFGYSV VHAYEKWSWV PNFAAFLVII AQLSRSGKFK
260 270 280 290 300
GGEWVGGATT AGGVLSFGSS VFGSAAGWAT YAADYTVYMP KTTSKYKIFF
310 320 330 340 350
SVVAGLAFPL FFTMILGAAC GMAALNDPTW KSYYDKNAMG GVIYAILVPN
360 370 380 390 400
SLNGFGQFCC VLLALSTVAN NVPGMYTVAL SAQALWAPLA KIPRVVWTMA
410 420 430 440 450
GNAATLGISI PATYYFDGFM ENFMDSIGYY LAIYIAIACS EHFIYRRSFS
460 470 480 490 500
AYNIDDWDNW EHLPIGIAGT AALIAGAFGV ALGMCQTYWV GEISRLIGEY
510 520 530
GGDIGFELGG SWAFIIYNIV RPLELKYFGR
Length:530
Mass (Da):57,327
Last modified:November 1, 1996 - v1
Checksum:i620FF2F2F3A2702D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X97346 Genomic DNA. Translation: CAA66033.1.
U18813 Genomic DNA. Translation: AAB64610.1.
BK006939 Genomic DNA. Translation: DAA07719.1.
RefSeqiNP_010982.1. NM_001180858.1.

Genome annotation databases

EnsemblFungiiYER060W-A; YER060W-A; YER060W-A.
GeneIDi856789.
KEGGisce:YER060W-A.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X97346 Genomic DNA. Translation: CAA66033.1 .
U18813 Genomic DNA. Translation: AAB64610.1 .
BK006939 Genomic DNA. Translation: DAA07719.1 .
RefSeqi NP_010982.1. NM_001180858.1.

3D structure databases

ProteinModelPortali Q12119.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 36802. 14 interactions.
DIPi DIP-8900N.
STRINGi 4932.YER060W-A.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YER060W-A ; YER060W-A ; YER060W-A .
GeneIDi 856789.
KEGGi sce:YER060W-A.

Organism-specific databases

CYGDi YER060w-a.
SGDi S000002958. FCY22.

Phylogenomic databases

eggNOGi COG1457.
GeneTreei ENSGT00390000004423.
HOGENOMi HOG000162981.
InParanoidi Q12119.
OrthoDBi EOG75QRD0.

Enzyme and pathway databases

BioCyci YEAST:G3O-30354-MONOMER.

Miscellaneous databases

NextBioi 983015.

Gene expression databases

Genevestigatori Q12119.

Family and domain databases

InterProi IPR001248. Cyt_pur_permease.
IPR012681. NCS1.
IPR026030. Pur-cyt_permease.
[Graphical view ]
Pfami PF02133. Transp_cyt_pur. 1 hit.
[Graphical view ]
PIRSFi PIRSF002744. Pur-cyt_permease. 1 hit.
TIGRFAMsi TIGR00800. ncs1. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Straub M.-L., Souciet J.-L., Potier S., de Montigny J.
    Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 28383 / FL100 / VTT C-80102.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.

Entry informationi

Entry nameiFCY22_YEAST
AccessioniPrimary (citable) accession number: Q12119
Secondary accession number(s): D3DLW5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome V
    Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

External Data

Dasty 3