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Q12119 (FCY22_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Purine-cytosine permease FCY22

Short name=PCP FCY22
Alternative name(s):
Cytosine/purine transport protein FCY22
Fluorocytosine resistance protein 22
Gene names
Name:FCY22
Synonyms:FCYX
Ordered Locus Names:YER060W-A
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length530 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Probable purine-cytosine permease By similarity.

Subcellular location

Membrane; Multi-pass membrane protein Probable.

Sequence similarities

Belongs to the purine-cytosine permease family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 530530Purine-cytosine permease FCY22
PRO_0000197922

Regions

Transmembrane96 – 11621Helical; Potential
Transmembrane119 – 13921Helical; Potential
Transmembrane162 – 18221Helical; Potential
Transmembrane197 – 21721Helical; Potential
Transmembrane220 – 24021Helical; Potential
Transmembrane263 – 28321Helical; Potential
Transmembrane298 – 31821Helical; Potential
Transmembrane345 – 36521Helical; Potential
Transmembrane372 – 39221Helical; Potential
Transmembrane396 – 41621Helical; Potential
Transmembrane418 – 43821Helical; Potential
Transmembrane463 – 48321Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q12119 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 620FF2F2F3A2702D

FASTA53057,327
        10         20         30         40         50         60 
MPEKLAMSMV DIKDAGSELR DLESGALDTK SSAADVYYEG VELHRTNEFI DNKPSFFNRI 

        70         80         90        100        110        120 
AAALNAETKG IEPVTEDEKN DDSILNAATI WFSANMVIVA YSVGALGPLV FGLNFGQSVL 

       130        140        150        160        170        180 
VIIFFNILGL IPVALFSLFG VELGLRQMIL SRYLAGNITA RFFSLVNVIA CVGWCVLNIS 

       190        200        210        220        230        240 
VSAQLLNMVN EGSGHNCPIW AGCLIIAGGT VLVTFFGYSV VHAYEKWSWV PNFAAFLVII 

       250        260        270        280        290        300 
AQLSRSGKFK GGEWVGGATT AGGVLSFGSS VFGSAAGWAT YAADYTVYMP KTTSKYKIFF 

       310        320        330        340        350        360 
SVVAGLAFPL FFTMILGAAC GMAALNDPTW KSYYDKNAMG GVIYAILVPN SLNGFGQFCC 

       370        380        390        400        410        420 
VLLALSTVAN NVPGMYTVAL SAQALWAPLA KIPRVVWTMA GNAATLGISI PATYYFDGFM 

       430        440        450        460        470        480 
ENFMDSIGYY LAIYIAIACS EHFIYRRSFS AYNIDDWDNW EHLPIGIAGT AALIAGAFGV 

       490        500        510        520        530 
ALGMCQTYWV GEISRLIGEY GGDIGFELGG SWAFIIYNIV RPLELKYFGR 

« Hide

References

« Hide 'large scale' references
[1]Straub M.-L., Souciet J.-L., Potier S., de Montigny J.
Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 28383 / FL100 / VTT C-80102.
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome V."
Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E., Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S., Hyman R.W. expand/collapse author list , Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X., Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y., Botstein D., Davis R.W.
Nature 387:78-81(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X97346 Genomic DNA. Translation: CAA66033.1.
U18813 Genomic DNA. Translation: AAB64610.1.
BK006939 Genomic DNA. Translation: DAA07719.1.
RefSeqNP_010982.1. NM_001180858.1.

3D structure databases

ProteinModelPortalQ12119.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid36802. 14 interactions.
DIPDIP-8900N.
STRING4932.YER060W-A.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYER060W-A; YER060W-A; YER060W-A.
GeneID856789.
KEGGsce:YER060W-A.

Organism-specific databases

CYGDYER060w-a.
SGDS000002958. FCY22.

Phylogenomic databases

eggNOGCOG1457.
GeneTreeENSGT00390000004423.
HOGENOMHOG000162981.
OMALSYWLAI.
OrthoDBEOG75QRD0.

Enzyme and pathway databases

BioCycYEAST:G3O-30354-MONOMER.

Gene expression databases

GenevestigatorQ12119.

Family and domain databases

InterProIPR001248. Cyt_pur_permease.
IPR012681. NCS1.
IPR026030. Pur-cyt_permease.
[Graphical view]
PfamPF02133. Transp_cyt_pur. 1 hit.
[Graphical view]
PIRSFPIRSF002744. Pur-cyt_permease. 1 hit.
TIGRFAMsTIGR00800. ncs1. 1 hit.
ProtoNetSearch...

Other

NextBio983015.

Entry information

Entry nameFCY22_YEAST
AccessionPrimary (citable) accession number: Q12119
Secondary accession number(s): D3DLW5
Entry history
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 1, 1996
Last modified: February 19, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome V

Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families