Q12110 (YL049_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YLR049C

Gene names

Ordered Locus Names:	YLR049C
ORF Names:	L2121

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	428 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Miscellaneous

Present with 339 molecules/cell in log phase SD medium. Ref.3

Ontologies

Keywords
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 428	428	Uncharacterized protein YLR049C		PRO_0000247204
Regions
	Compositional bias	89 – 97	9	Poly-Ser
Amino acid modifications
	Modified residue	127	1	Phosphoserine Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Q12110 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 9414BB6CF379E682	FASTA	428	49,493
	10 20 30 40 50 60 MVNNIMHEYV PPSQRLFHSR HRITRNDLKE EALHSGTTDW TTILDTTIDK DTNLISYAVP 70 80 90 100 110 120 IIDNFAIPRA NSQGSPVAPS PNHRSTMYSS SSSSASSVFS DGLFTPNNNR NSSGSSSLVI 130 140 150 160 170 180 RPQKNLSVDS LIQENKRKIN SEKESLSLIA NNNDETLCTH TDPSIQNLIK SETKRNILNL 190 200 210 220 230 240 KFQNRNLFRR ELKLEKFWSN LRSCHTSGDE TDLLLVISKH NLYWFGIPND FRLPIYKRCL 250 260 270 280 290 300 YHYSELDEAG FFSQYANNSL YLAIRKCCNN EEQETLSRSI FINLTKNVTW LNSRFDDNKD 310 320 330 340 350 360 NKNSYTVTEG KFYQDFPNLY YHLKDKLKLN VIMDFIKPVI RNFMTNALNK HKLDGIGLEL 370 380 390 400 410 420 LDILIVTTYY GPNKINAFLM DTFILNLLKQ CHYKFFVSNI SELVIQISKI DCDLVILLED LRSRIDLD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XII." Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H. , Hilger F., Kleine K., Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., Hani J., Hoheisel J.D. Nature 387:87-90(1997) [PubMed: 9169871] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[4]	"Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway." Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J., Mann M., Jensen O.N. Mol. Cell. Proteomics 4:310-327(2005) [PubMed: 15665377] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-127, MASS SPECTROMETRY. Strain: YAL6B.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z73221 Genomic DNA. Translation: CAA97579.1. X94607 Genomic DNA. Translation: CAA64296.1. BK006945 Genomic DNA. Translation: DAA09367.1.
PIR	S61623.
RefSeq	NP_013150.1. NM_001181936.1.
3D structure databases
ProteinModelPortal	Q12110.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-1211N.
IntAct	Q12110. 2 interactions.
MINT	MINT-387384.
STRING	Q12110.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YLR049C; YLR049C; YLR049C.
GeneID	850738.
KEGG	sce:YLR049C.
NMPDR	fig|4932.3.peg.4141.
Organism-specific databases
CYGD	YLR049c.
SGD	S000004039. YLR049C.
Phylogenomic databases
eggNOG	fuNOG13662.
HOGENOM	HBG202426.
OMA	YAVPIID.
OrthoDB	EOG479JHR.
Gene expression databases
ArrayExpress	Q12110.
Genevestigator	Q12110.
GermOnline	YLR049C. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other
NextBio	966846.

Entry information

Entry name

YL049_YEAST

Accession

Primary (citable) accession number: Q12110
Secondary accession number(s): D6VY51

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2006
Last sequence update:	November 1, 1996
Last modified:	December 14, 2011
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program