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Protein

Ribosome biogenesis protein TSR3

Gene

TSR3

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Ribosome biogenesis protein required for processing 35S pre-rRNA at site D.UniRule annotation1 Publication

Miscellaneous

Present with 3610 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • transferase activity Source: SGD

GO - Biological processi

  • maturation of SSU-rRNA Source: SGD

Keywordsi

Biological processRibosome biogenesis, rRNA processing

Enzyme and pathway databases

BioCyciYEAST:G3O-33556-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosome biogenesis protein TSR3UniRule annotation
Alternative name(s):
20S rRNA accumulation protein 3
Gene namesi
Name:TSR3UniRule annotation
Ordered Locus Names:YOR006C
ORF Names:UND313
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOR006C.
SGDiS000005532. TSR3.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000944261 – 313Ribosome biogenesis protein TSR3Add BLAST313

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei286PhosphoserineCombined sources1
Modified residuei289PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ12094.
PRIDEiQ12094.

PTM databases

iPTMnetiQ12094.

Interactioni

Protein-protein interaction databases

BioGridi34409. 135 interactors.
DIPiDIP-1251N.
IntActiQ12094. 8 interactors.
MINTiMINT-395199.
STRINGi4932.YOR006C.

Structurei

3D structure databases

ProteinModelPortaliQ12094.
SMRiQ12094.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TSR3 family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000014665.
InParanoidiQ12094.
KOiK09140.
OMAiNGHKSKQ.
OrthoDBiEOG092C5BZ8.

Family and domain databases

HAMAPiMF_01116. TSR3. 1 hit.
InterProiView protein in InterPro
IPR022968. Rbsm_biogenesis.
IPR007209. RNaseL-inhib_metal-bd_dom.
IPR007177. TDD_dom.
PANTHERiPTHR20426. PTHR20426. 1 hit.
PfamiView protein in Pfam
PF04034. Ribo_biogen_C. 1 hit.
PF04068. RLI. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD016638. DUF367. 1 hit.

Sequencei

Sequence statusi: Complete.

Q12094-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKGKNKMHE PKNGRPQRGA NGHSSRQNHR RMEMKYDNSE KMKFPVKLAM
60 70 80 90 100
WDFDHCDPKR CSGKKLERLG LIKSLRVGQK FQGIVVSPNG KGVVCPDDLE
110 120 130 140 150
IVEQHGASVV ECSWARLEEV PFNKIGGKHE RLLPYLVAAN QVNYGRPWRL
160 170 180 190 200
NCVEALAACF AIVGRMDWAS ELLSHFSWGM GFLELNKELL EIYQQCTDCD
210 220 230 240 250
SVKRAEEEWL QKLEKETQER KSRAKEEDIW MMGNINRRGN GSQSDTSESE
260 270 280 290 300
ENSEQSDLEG NNQCIEYDSL GNAIRIDNMK SREAQSEESE DEESGSKENG
310
EPLSYDPLGN LIR
Length:313
Mass (Da):35,686
Last modified:November 1, 1996 - v1
Checksum:i6DF4703EA7252910
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U43491 Genomic DNA. Translation: AAC49486.1.
Z74914 Genomic DNA. Translation: CAA99194.1.
BK006948 Genomic DNA. Translation: DAA10788.1.
PIRiS61990.
RefSeqiNP_014648.1. NM_001183425.1.

Genome annotation databases

EnsemblFungiiYOR006C; YOR006C; YOR006C.
GeneIDi854167.
KEGGisce:YOR006C.

Similar proteinsi

Entry informationi

Entry nameiTSR3_YEAST
AccessioniPrimary (citable) accession number: Q12094
Secondary accession number(s): D6W272
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: September 27, 2017
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names