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Protein

Ribosome biogenesis protein TSR3

Gene

TSR3

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Ribosome biogenesis protein required for processing 35S pre-rRNA at site D.UniRule annotation1 Publication

Miscellaneous

Present with 3610 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • transferase activity Source: SGD

GO - Biological processi

  • maturation of SSU-rRNA Source: SGD

Keywordsi

Biological processRibosome biogenesis, rRNA processing

Enzyme and pathway databases

BioCyciYEAST:G3O-33556-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosome biogenesis protein TSR3UniRule annotation
Alternative name(s):
20S rRNA accumulation protein 3
Gene namesi
Name:TSR3UniRule annotation
Ordered Locus Names:YOR006C
ORF Names:UND313
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOR006C
SGDiS000005532 TSR3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000944261 – 313Ribosome biogenesis protein TSR3Add BLAST313

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei286PhosphoserineCombined sources1
Modified residuei289PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ12094
PaxDbiQ12094
PRIDEiQ12094

PTM databases

iPTMnetiQ12094

Interactioni

Protein-protein interaction databases

BioGridi34409, 136 interactors
DIPiDIP-1251N
IntActiQ12094, 7 interactors
MINTiQ12094
STRINGi4932.YOR006C

Structurei

3D structure databases

ProteinModelPortaliQ12094
SMRiQ12094
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TSR3 family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000014665
InParanoidiQ12094
KOiK09140
OMAiSNGHKSK
OrthoDBiEOG092C5BZ8

Family and domain databases

HAMAPiMF_01116 TSR3, 1 hit
InterProiView protein in InterPro
IPR022968 Rbsm_biogenesis
IPR007209 RNaseL-inhib_metal-bd_dom
IPR007177 TDD_dom
PANTHERiPTHR20426 PTHR20426, 1 hit
PfamiView protein in Pfam
PF04034 Ribo_biogen_C, 1 hit
PF04068 RLI, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD016638 DUF367, 1 hit

Sequencei

Sequence statusi: Complete.

Q12094-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKGKNKMHE PKNGRPQRGA NGHSSRQNHR RMEMKYDNSE KMKFPVKLAM
60 70 80 90 100
WDFDHCDPKR CSGKKLERLG LIKSLRVGQK FQGIVVSPNG KGVVCPDDLE
110 120 130 140 150
IVEQHGASVV ECSWARLEEV PFNKIGGKHE RLLPYLVAAN QVNYGRPWRL
160 170 180 190 200
NCVEALAACF AIVGRMDWAS ELLSHFSWGM GFLELNKELL EIYQQCTDCD
210 220 230 240 250
SVKRAEEEWL QKLEKETQER KSRAKEEDIW MMGNINRRGN GSQSDTSESE
260 270 280 290 300
ENSEQSDLEG NNQCIEYDSL GNAIRIDNMK SREAQSEESE DEESGSKENG
310
EPLSYDPLGN LIR
Length:313
Mass (Da):35,686
Last modified:November 1, 1996 - v1
Checksum:i6DF4703EA7252910
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U43491 Genomic DNA Translation: AAC49486.1
Z74914 Genomic DNA Translation: CAA99194.1
BK006948 Genomic DNA Translation: DAA10788.1
PIRiS61990
RefSeqiNP_014648.1, NM_001183425.1

Genome annotation databases

EnsemblFungiiYOR006C; YOR006C; YOR006C
GeneIDi854167
KEGGisce:YOR006C

Similar proteinsi

Entry informationi

Entry nameiTSR3_YEAST
AccessioniPrimary (citable) accession number: Q12094
Secondary accession number(s): D6W272
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health