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Protein

Ribosome biogenesis protein TSR3

Gene

TSR3

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Ribosome biogenesis protein required for processing 35S pre-rRNA at site D.UniRule annotation1 Publication

GO - Biological processi

  • maturation of SSU-rRNA Source: SGD
Complete GO annotation...

Keywords - Biological processi

Ribosome biogenesis, rRNA processing

Enzyme and pathway databases

BioCyciYEAST:G3O-33556-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosome biogenesis protein TSR3UniRule annotation
Alternative name(s):
20S rRNA accumulation protein 3
Gene namesi
Name:TSR3UniRule annotation
Ordered Locus Names:YOR006C
ORF Names:UND313
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOR006C.
SGDiS000005532. TSR3.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 313313Ribosome biogenesis protein TSR3PRO_0000094426Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei286 – 2861PhosphoserineCombined sources
Modified residuei289 – 2891PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ12094.

PTM databases

iPTMnetiQ12094.

Interactioni

Protein-protein interaction databases

BioGridi34409. 50 interactions.
DIPiDIP-1251N.
IntActiQ12094. 6 interactions.
MINTiMINT-395199.

Structurei

3D structure databases

ProteinModelPortaliQ12094.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TSR3 family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000014665.
InParanoidiQ12094.
KOiK09140.
OMAiCFAIVGR.
OrthoDBiEOG092C5BZ8.

Family and domain databases

HAMAPiMF_01116. TSR3. 1 hit.
InterProiIPR022968. Rbsm_biogenesis.
IPR007209. RNaseL-inhib_metal-bd_dom.
IPR007177. TDD_dom.
[Graphical view]
PANTHERiPTHR20426. PTHR20426. 1 hit.
PfamiPF04034. DUF367. 1 hit.
PF04068. RLI. 1 hit.
[Graphical view]
ProDomiPD016638. DUF367. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Q12094-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKGKNKMHE PKNGRPQRGA NGHSSRQNHR RMEMKYDNSE KMKFPVKLAM
60 70 80 90 100
WDFDHCDPKR CSGKKLERLG LIKSLRVGQK FQGIVVSPNG KGVVCPDDLE
110 120 130 140 150
IVEQHGASVV ECSWARLEEV PFNKIGGKHE RLLPYLVAAN QVNYGRPWRL
160 170 180 190 200
NCVEALAACF AIVGRMDWAS ELLSHFSWGM GFLELNKELL EIYQQCTDCD
210 220 230 240 250
SVKRAEEEWL QKLEKETQER KSRAKEEDIW MMGNINRRGN GSQSDTSESE
260 270 280 290 300
ENSEQSDLEG NNQCIEYDSL GNAIRIDNMK SREAQSEESE DEESGSKENG
310
EPLSYDPLGN LIR
Length:313
Mass (Da):35,686
Last modified:November 1, 1996 - v1
Checksum:i6DF4703EA7252910
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U43491 Genomic DNA. Translation: AAC49486.1.
Z74914 Genomic DNA. Translation: CAA99194.1.
BK006948 Genomic DNA. Translation: DAA10788.1.
PIRiS61990.
RefSeqiNP_014648.1. NM_001183425.1.

Genome annotation databases

EnsemblFungiiYOR006C; YOR006C; YOR006C.
GeneIDi854167.
KEGGisce:YOR006C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U43491 Genomic DNA. Translation: AAC49486.1.
Z74914 Genomic DNA. Translation: CAA99194.1.
BK006948 Genomic DNA. Translation: DAA10788.1.
PIRiS61990.
RefSeqiNP_014648.1. NM_001183425.1.

3D structure databases

ProteinModelPortaliQ12094.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34409. 50 interactions.
DIPiDIP-1251N.
IntActiQ12094. 6 interactions.
MINTiMINT-395199.

PTM databases

iPTMnetiQ12094.

Proteomic databases

MaxQBiQ12094.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYOR006C; YOR006C; YOR006C.
GeneIDi854167.
KEGGisce:YOR006C.

Organism-specific databases

EuPathDBiFungiDB:YOR006C.
SGDiS000005532. TSR3.

Phylogenomic databases

GeneTreeiENSGT00390000014665.
InParanoidiQ12094.
KOiK09140.
OMAiCFAIVGR.
OrthoDBiEOG092C5BZ8.

Enzyme and pathway databases

BioCyciYEAST:G3O-33556-MONOMER.

Miscellaneous databases

PROiQ12094.

Family and domain databases

HAMAPiMF_01116. TSR3. 1 hit.
InterProiIPR022968. Rbsm_biogenesis.
IPR007209. RNaseL-inhib_metal-bd_dom.
IPR007177. TDD_dom.
[Graphical view]
PANTHERiPTHR20426. PTHR20426. 1 hit.
PfamiPF04034. DUF367. 1 hit.
PF04068. RLI. 1 hit.
[Graphical view]
ProDomiPD016638. DUF367. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Entry informationi

Entry nameiTSR3_YEAST
AccessioniPrimary (citable) accession number: Q12094
Secondary accession number(s): D6W272
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 3610 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.