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Protein

Damage response protein 1

Gene

DAP1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 6300 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • heme binding Source: SGD

GO - Biological processi

  • regulation of ergosterol biosynthetic process Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-34066-MONOMER
ReactomeiR-SCE-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Recommended name:
Damage response protein 1
Gene namesi
Name:DAP1
Ordered Locus Names:YPL170W
ORF Names:P2515
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPL170W
SGDiS000006091 DAP1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001217471 – 152Damage response protein 1Add BLAST152

Proteomic databases

MaxQBiQ12091
PaxDbiQ12091
PRIDEiQ12091
TopDownProteomicsiQ12091

Interactioni

Protein-protein interaction databases

BioGridi3601394 interactors.
DIPiDIP-5226N
IntActiQ12091 7 interactors.
MINTiQ12091
STRINGi4932.YPL170W

Structurei

3D structure databases

ProteinModelPortaliQ12091
SMRiQ12091
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini46 – 145Cytochrome b5 heme-bindingAdd BLAST100

Domaini

The cytochrome b5 heme-binding domain lacks the conserved iron-binding His residues at positions 81 and 105.By similarity

Sequence similaritiesi

Belongs to the cytochrome b5 family. MAPR subfamily.Curated

Phylogenomic databases

GeneTreeiENSGT00730000110959
HOGENOMiHOG000187840
InParanoidiQ12091
KOiK17278
OMAiWMPKAHP
OrthoDBiEOG092C53VE

Family and domain databases

Gene3Di3.10.120.101 hit
InterProiView protein in InterPro
IPR001199 Cyt_B5-like_heme/steroid-bd
IPR036400 Cyt_B5-like_heme/steroid_sf
PfamiView protein in Pfam
PF00173 Cyt-b5, 1 hit
SMARTiView protein in SMART
SM01117 Cyt-b5, 1 hit
SUPFAMiSSF55856 SSF55856, 1 hit

Sequencei

Sequence statusi: Complete.

Q12091-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFIKNLLFG GVKTSEDPTG LTGNGASNTN DSNKGSEPVV AGNFFPRTLS
60 70 80 90 100
KFNGHDDEKI FIAIRGKVYD CTRGRQFYGP SGPYTNFAGH DASRGLALNS
110 120 130 140 150
FDLDVIKDWD QPIDPLDDLT KEQIDALDEW QEHFENKYPC IGTLIPEPGV

NV
Length:152
Mass (Da):16,758
Last modified:November 1, 1996 - v1
Checksum:i3E3CAC2403C3246F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X96770 Genomic DNA Translation: CAA65551.1
Z73526 Genomic DNA Translation: CAA97876.1
AY558521 Genomic DNA Translation: AAS56847.1
BK006949 Genomic DNA Translation: DAA11264.1
PIRiS65181
RefSeqiNP_015155.1, NM_001183984.1

Genome annotation databases

EnsemblFungiiYPL170W; YPL170W; YPL170W
GeneIDi855933
KEGGisce:YPL170W

Similar proteinsi

Entry informationi

Entry nameiDAP1_YEAST
AccessioniPrimary (citable) accession number: Q12091
Secondary accession number(s): D6W3J8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 143 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome