Q12062 (Q12062_ASPPA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Versicolorin B synthase EMBL AAC49319.1

Gene names

Name:	vbs EMBL AAC49319.1
Synonyms:	aflK EMBL AAS66012.1

Organism

Aspergillus parasiticus EMBL AAC49319.1

Taxonomic identifier

5067 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus

Protein attributes

Sequence length	643 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	alcohol metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	choline dehydrogenase activity Inferred from electronic annotation. Source: InterPro flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q12062 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 4B903BA6A0F39D11	FASTA	643	70,271
	10 20 30 40 50 60 MGRNWFQVTA MAVVPVVGIM AAVNPTILSS AASSLPSLGA MFTSDDFASQ MDGRIQAQGL 70 80 90 100 110 120 LSSHFGMYGW PGQSFDYVIV GGGTAGLAMA RRLSQDGTAS VAVIEAGGFY ETDAGNATEV 130 140 150 160 170 180 PMYLFNYFFD NGKVKNPLFD WYQYTTPQPG LAQREMFYMQ GKTLGGSTAR GAMLYHRGSK 190 200 210 220 230 240 GAYDMWADHV GDDSYRWDKW LPYFQKSVHF SGPETNPRPA NATALNDNTA FTASGGPVHV 250 260 270 280 290 300 GYPFQVNAIS SWVDRALAKM GFPEAQGFSN GNLLGRSYIT HTINPYTRRR ETASSSYLRE 310 320 330 340 350 360 ALMESNNLNI FTRTLVKRVL FDDQNRATGV TVNTDGFEWQ IGARKEVILS AGVMRSPQLL 370 380 390 400 410 420 MVSGIGPKDH LEQLGIPVRS DLSGVGQNMQ DTIILGPTVP VKVESHSQLM GNKETLPRAI 430 440 450 460 470 480 REYNEQRKGL LTNPGQDYFA FEKHQPGMLK ESTAADIDAA FPDDWPTFSY IALDDTFVPQ 490 500 510 520 530 540 YDGKNYFSMS AALMTPFSRG TVTINSNDTA NPPIVDPQWL ADPRDQEMAV AAFRRCREIV 550 560 570 580 590 600 ASDVMREVVA GPEILPGPQY QTDEEILNYI AETSDAYYAG VGTCAMGKAD DPKAVVDSKA 610 620 630 640 RVLGVKGLRI VDASIFPFAI DGQPMGTVYA LAEKIAAEMM AGQ

References

[1]	"Isolation and characterization of the versicolorin B synthase gene from Aspergillus parasiticus. Expansion of the aflatoxin b1 biosynthetic gene cluster." Silva J.C., Minto R.E., Barry C.E. 3rd, Holland K.A., Townsend C.A. J. Biol. Chem. 271:13600-13608(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Su-1 EMBL AAC49318.1 and SU-1 EMBL AAC49319.1.
[2]	"Genes encoding cytochrome P450 and monooxigenase enzymes define one end of the aflatoxin pathway gene cluster in Aspergillus parasiticus." Yu J., Chang P.-K., Bhatnagar D., Cleveland T.E. Appl. Microbiol. Biotechnol. 53:583-590(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: SU-1 EMBL AAS66012.1.
[3]	"Clustered pathway genes in aflatoxin biosynthesis." Yu J., Chang P.K., Ehrlich K.C., Cary J.W., Bhatnagar D., Cleveland T.E., Payne G.A., Linz J.E., Woloshuk C.P., Bennett J.W. Appl. Environ. Microbiol. 70:1253-1262(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: SU-1 EMBL AAS66012.1.
[4]	"Completed sequence of aflatoxin pathway gene cluster in Aspergillus parasiticus." Yu J., Bhatnagar D., Cleveland T.E. FEBS Lett. 564:126-130(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: SU-1 EMBL AAS66012.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U51327 Genomic DNA. Translation: AAC49318.1. U51328 mRNA. Translation: AAC49319.1. AY371490 Genomic DNA. Translation: AAS66012.1.
3D structure databases
ProteinModelPortal	Q12062.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
BioCyc	MetaCyc:MONOMER-14040.
Family and domain databases
InterPro	IPR012132. GMC_OxRdtase. IPR000172. GMC_OxRdtase_N. IPR007867. GMC_OxRtase_C. [Graphical view]
Pfam	PF05199. GMC_oxred_C. 1 hit. PF00732. GMC_oxred_N. 1 hit. [Graphical view]
PIRSF	PIRSF000137. Alcohol_oxidase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q12062_ASPPA

Accession

Primary (citable) accession number: Q12062

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)