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Protein

Regulator of calcineurin 2

Gene

RCN2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciYEAST:G3O-33720-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Regulator of calcineurin 2
Alternative name(s):
Weak suppressor of PAT1 ts protein 1
Gene namesi
Name:RCN2
Synonyms:WSP1
Ordered Locus Names:YOR220W
ORF Names:YOR50-10
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOR220W.
SGDiS000005746. RCN2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002376411 – 265Regulator of calcineurin 2Add BLAST265

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei104PhosphoserineCombined sources1
Modified residuei110PhosphoserineCombined sources1
Modified residuei132PhosphothreonineCombined sources1
Modified residuei152PhosphoserineCombined sources1
Modified residuei157PhosphoserineCombined sources1
Modified residuei160PhosphoserineCombined sources1
Modified residuei183PhosphoserineCombined sources1
Modified residuei187PhosphoserineCombined sources1
Modified residuei193PhosphoserineCombined sources1
Modified residuei201PhosphoserineCombined sources1
Modified residuei255PhosphoserineCombined sources1

Post-translational modificationi

Phosphorylation of Ser-152 and Ser-160 is induced 2-fold in response to mating pheromone.

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ12044.
PRIDEiQ12044.

PTM databases

iPTMnetiQ12044.

Interactioni

Protein-protein interaction databases

BioGridi34614. 20 interactors.
DIPiDIP-1996N.
IntActiQ12044. 3 interactors.
MINTiMINT-384402.

Structurei

3D structure databases

ProteinModelPortaliQ12044.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi141 – 204Ser-richAdd BLAST64

Phylogenomic databases

HOGENOMiHOG000066002.
InParanoidiQ12044.
OMAiRCAREHY.
OrthoDBiEOG092C5MVU.

Sequencei

Sequence statusi: Complete.

Q12044-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANQKQMRTQ ILITDIPSGK FTSKWPTQLE KTLFKEQFPN LQSHLQYYTP
60 70 80 90 100
LPFLNRIIII FDNEDDTLQV FKFLQELLAK ENSGPMKLFV TESLLNNQHP
110 120 130 140 150
RSRSTDDAVS LQDNNLALLE DHRNKPLLSI NTDPGVTGVD SSSLNKGGSS
160 170 180 190 200
LSPDKSSLES PTMLKLSTDS KPFSYQEPLP KLSRSSSSTS NLSLNRSSQT
210 220 230 240 250
SLPSQLENKD KSASGTKCLF ASKPLGLTID TSTRSNAASC TENDVNATAS
260
NPPKSPSITV NEFFH
Length:265
Mass (Da):29,256
Last modified:November 1, 1996 - v1
Checksum:i4A184C5C1218A617
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X92441 Genomic DNA. Translation: CAA63183.1.
Z75128 Genomic DNA. Translation: CAA99438.1.
AY557757 Genomic DNA. Translation: AAS56083.1.
BK006948 Genomic DNA. Translation: DAA10991.1.
PIRiS60947.
RefSeqiNP_014863.1. NM_001183639.1.

Genome annotation databases

EnsemblFungiiYOR220W; YOR220W; YOR220W.
GeneIDi854395.
KEGGisce:YOR220W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X92441 Genomic DNA. Translation: CAA63183.1.
Z75128 Genomic DNA. Translation: CAA99438.1.
AY557757 Genomic DNA. Translation: AAS56083.1.
BK006948 Genomic DNA. Translation: DAA10991.1.
PIRiS60947.
RefSeqiNP_014863.1. NM_001183639.1.

3D structure databases

ProteinModelPortaliQ12044.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34614. 20 interactors.
DIPiDIP-1996N.
IntActiQ12044. 3 interactors.
MINTiMINT-384402.

PTM databases

iPTMnetiQ12044.

Proteomic databases

MaxQBiQ12044.
PRIDEiQ12044.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYOR220W; YOR220W; YOR220W.
GeneIDi854395.
KEGGisce:YOR220W.

Organism-specific databases

EuPathDBiFungiDB:YOR220W.
SGDiS000005746. RCN2.

Phylogenomic databases

HOGENOMiHOG000066002.
InParanoidiQ12044.
OMAiRCAREHY.
OrthoDBiEOG092C5MVU.

Enzyme and pathway databases

BioCyciYEAST:G3O-33720-MONOMER.

Miscellaneous databases

PROiQ12044.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiRCN2_YEAST
AccessioniPrimary (citable) accession number: Q12044
Secondary accession number(s): D6W2S5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 967 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.