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Protein

Probable mitochondrial transport protein FSF1

Gene

FSF1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Transports citrate. Potential iron transporter (By similarity).By similarity

Miscellaneous

Present with 9290 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processIon transport, Iron transport, Transport
LigandIron

Enzyme and pathway databases

BioCyciYEAST:G3O-33761-MONOMER

Protein family/group databases

TCDBi2.A.54.1.4 the mitochondrial tricarboxylate carrier (mtc) family

Names & Taxonomyi

Protein namesi
Recommended name:
Probable mitochondrial transport protein FSF1
Alternative name(s):
Fungal sideroflexin-1
Gene namesi
Name:FSF1
Ordered Locus Names:YOR271C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOR271C
SGDiS000005797 FSF1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei98 – 118HelicalSequence analysisAdd BLAST21
Transmembranei143 – 163HelicalSequence analysisAdd BLAST21
Transmembranei179 – 199HelicalSequence analysisAdd BLAST21
Transmembranei272 – 292HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
ChainiPRO_00002376422 – 327Probable mitochondrial transport protein FSF1Add BLAST326

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiQ12029
PaxDbiQ12029
PRIDEiQ12029

PTM databases

iPTMnetiQ12029

Interactioni

Protein-protein interaction databases

BioGridi34660, 64 interactors
DIPiDIP-3828N
IntActiQ12029, 22 interactors
STRINGi4932.YOR271C

Structurei

3D structure databases

ProteinModelPortaliQ12029
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the sideroflexin family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00390000002026
HOGENOMiHOG000203440
InParanoidiQ12029
OMAiWQVANQS
OrthoDBiEOG092C3GKQ

Family and domain databases

InterProiView protein in InterPro
IPR004686 Mtc
PANTHERiPTHR11153 PTHR11153, 1 hit
PfamiView protein in Pfam
PF03820 Mtc, 1 hit
TIGRFAMsiTIGR00798 mtc, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q12029-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSVPGPID LPESRYDLST YWGRIRHCAE ISDPTMLLTT EKDLAHAREI
60 70 80 90 100
ISAYRHGELK ETTPEFWRAK KQLDSTVHPD TGKTVLLPFR MSSNVLSNLV
110 120 130 140 150
VTVGMLTPGL GTAGTVFWQW ANQSLNVAVN SANANKSHPM STSQLLTNYA
160 170 180 190 200
AAVTASCGVA LGLNNLVPRL KNISPHSKLI LGRLVPFAAV VSAGIVNVFL
210 220 230 240 250
MRGNEIRKGI SVFDSNGDEV GKSKKAAFMA VGETALSRVI NATPTMVIPP
260 270 280 290 300
LILVRLQRGV LKGKSLGVQT LANLGLISVT MFSALPFALG IFPQRQAIHL
310 320
NKLEPELHGK KDKDGKPIEK VYFNRGI
Length:327
Mass (Da):35,414
Last modified:November 1, 1996 - v1
Checksum:iFD175626E63B8619
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X89633 Genomic DNA Translation: CAA61777.1
Z75179 Genomic DNA Translation: CAA99495.1
BK006948 Genomic DNA Translation: DAA11037.1
PIRiS67168
RefSeqiNP_014914.1, NM_001183690.1

Genome annotation databases

EnsemblFungiiYOR271C; YOR271C; YOR271C
GeneIDi854445
KEGGisce:YOR271C

Similar proteinsi

Entry informationi

Entry nameiFSF1_YEAST
AccessioniPrimary (citable) accession number: Q12029
Secondary accession number(s): D6W2X1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health