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Q11Y69 (PSD_CYTH3) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:CHU_0357
OrganismCytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) [Complete proteome] [HAMAP]
Taxonomic identifier269798 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Cytophagia › Cytophagales › Cytophagaceae › Cytophaga

Protein attributes

Sequence length220 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 187187Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000262205
Chain188 – 22033Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000262206

Sites

Site187 – 1882Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue1881Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q11Y69 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: 40BE989010C777CF

FASTA22025,376
        10         20         30         40         50         60 
MTIHKEGYRS LFYVSAFLFL LNFLIYYFFP EASILQKTVL VISLLIFLVV LQFFRNPSRT 

        70         80         90        100        110        120 
IEINDNQIIA PADGKVVVIE EVIETEYFNE KRRQISIFMS PFNVHSNRNA VSGIVKFFKY 

       130        140        150        160        170        180 
HPGKFLVAWH PKSSTENERT TTVVQTKNNE QILMRQIAGA LARRIVWYID ENSKVTQGEE 

       190        200        210        220 
FGFIKFGSRV DLFIPLDAKV KVSLNQTTVG GKTVIAEFYS

« Hide

References

[1]"Genome sequence of the cellulolytic gliding bacterium Cytophaga hutchinsonii."
Xie G., Bruce D.C., Challacombe J.F., Chertkov O., Detter J.C., Gilna P., Han C.S., Lucas S., Misra M., Myers G.L., Richardson P., Tapia R., Thayer N., Thompson L.S., Brettin T.S., Henrissat B., Wilson D.B., McBride M.J.
Appl. Environ. Microbiol. 73:3536-3546(2007) [PubMed: 17400776] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33406 / NCIMB 9469.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000383 Genomic DNA. Translation: ABG57647.1.
RefSeqYP_676987.1. NC_008255.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ11Y69.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4186049.
GenomeReviewsGene locus CHU_0357 in contig CP000383_GR.
KEGGchu:CHU_0357.
NMPDRfig|269798.12.peg.341.
PATRIC21591541. VBICytHut34013_0348.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0688.
HOGENOMHBG541103.
OMAIFMSVFN.
ProtClustDBPRK05305.

Enzyme and pathway databases

BioCycCHUT269798:CHU_0357-MONOMER.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00164. PS_decarb_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_CYTH3
AccessionPrimary (citable) accession number: Q11Y69
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: August 22, 2006
Last modified: January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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