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Protein

Guanylate kinase

Gene

gmk

Organism
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 17ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCHUT269798:G1G6N-596-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:CHU_0599
OrganismiCytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Taxonomic identifieri269798 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCytophagaceaeCytophaga
Proteomesi
  • UP000001822 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002663121 – 192Guanylate kinaseAdd BLAST192

Interactioni

Protein-protein interaction databases

STRINGi269798.CHU_0599

Structurei

3D structure databases

ProteinModelPortaliQ11XI0
SMRiQ11XI0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 184Guanylate kinase-likeUniRule annotationAdd BLAST182

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UHA Bacteria
COG0194 LUCA
HOGENOMiHOG000037640
KOiK00942
OMAiAGNYYGT
OrthoDBiPOG091H01Q4

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q11XI0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGKLFIFSA PSGSGKTTVV QHLLNTDPRI GFSISACTRE MRESKEANGK
60 70 80 90 100
DYYFLSVDEF ERRIQNNEFV EWEEVYPGRY YGTLRSEVQR IWDMGKHVIF
110 120 130 140 150
DVDVKGGLSL KEQFGDKALS VFVKVPSIEE LQKRLIDRNT ESEDSLKARL
160 170 180 190
EKMKYESSFQ DQFDVILVND RLEETFVKAH QLIDHFLENN SK
Length:192
Mass (Da):22,374
Last modified:August 22, 2006 - v1
Checksum:iE2D52BA2AAC96C9C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000383 Genomic DNA Translation: ABG57886.1
RefSeqiWP_011584002.1, NZ_FPJX01000001.1

Genome annotation databases

EnsemblBacteriaiABG57886; ABG57886; CHU_0599
KEGGichu:CHU_0599

Similar proteinsi

Entry informationi

Entry nameiKGUA_CYTH3
AccessioniPrimary (citable) accession number: Q11XI0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: August 22, 2006
Last modified: March 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health