ID   RLMF_CYTH3              Reviewed;         322 AA.
AC   Q11XA9;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   16-JUN-2009, entry version 22.
DE   RecName: Full=Ribosomal RNA large subunit methyltransferase F;
DE            EC=2.1.1.48;
DE   AltName: Full=23S rRNA mA1618 methyltransferase;
DE   AltName: Full=rRNA adenine N-6-methyltransferase;
GN   Name=rlmF; OrderedLocusNames=CHU_0670;
OS   Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469).
OC   Bacteria; Bacteroidetes; Sphingobacteria; Sphingobacteriales;
OC   Flexibacteraceae; Cytophaga.
OX   NCBI_TaxID=269798;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17400776; DOI=10.1128/AEM.00225-07;
RA   Xie G., Bruce D.C., Challacombe J.F., Chertkov O., Detter J.C.,
RA   Gilna P., Han C.S., Lucas S., Misra M., Myers G.L., Richardson P.,
RA   Tapia R., Thayer N., Thompson L.S., Brettin T.S., Henrissat B.,
RA   Wilson D.B., McBride M.J.;
RT   "Genome sequence of the cellulolytic gliding bacterium Cytophaga
RT   hutchinsonii.";
RL   Appl. Environ. Microbiol. 73:3536-3546(2007).
CC   -!- FUNCTION: Specifically methylates the adenine in position 1618 of
CC       23S rRNA (By similarity).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-
CC       homocysteine + rRNA containing N(6)-methyladenine.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC       METT10D/rlmF family.
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DR   EMBL; CP000383; ABG57957.1; -; Genomic_DNA.
DR   RefSeq; YP_677297.1; -.
DR   GeneID; 4185673; -.
DR   GenomeReviews; CP000383_GR; CHU_0670.
DR   KEGG; chu:CHU_0670; -.
DR   NMPDR; fig|269798.12.peg.637; -.
DR   HOGENOM; Q11XA9; -.
DR   OMA; Q11XA9; LNFGGQN.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008988; F:rRNA (adenine-N6-)-methyltransferase activity; IEA:HAMAP.
DR   GO; GO:0000154; P:rRNA modification; IEA:InterPro.
DR   HAMAP; MF_01848; -; 1.
DR   InterPro; IPR016909; S-AdoMet-dep_MeTrfase_YbiN_prd.
DR   InterPro; IPR010286; SAM-Mtase_prd.
DR   PANTHER; PTHR13393; DUF890; 1.
DR   Pfam; PF05971; Methyltransf_10; 1.
DR   PIRSF; PIRSF029038; Mtase_YbiN_prd; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Methyltransferase; rRNA processing;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN         1    322       Ribosomal RNA large subunit
FT                                methyltransferase F.
FT                                /FTId=PRO_0000349900.
SQ   SEQUENCE   322 AA;  35944 MW;  31F267FEE478B215 CRC64;
     MAEKNKKEHP VTKDRLHPRN KHRERYDFDA LIATTPELAQ YVTLNIYNDQ SIDFFNPAAV
     LCLNQALLKH YYGIDEWNIP EGYLCPPIPG RADYIHNIAA LLGTSANDVI PVGPAIKCLD
     IGVGANCVYP IIGNNEYGWS FVGADVDPVS VASAKNIVDK NKVLQGNVEI RLQNHPLDIF
     YGIIGEGERF DVTICNPPFH ASAEDAAAGT LRKLSNLQHK KVTKANLNFG GQHNELWCEG
     GESAFVREMI LESKKFAASC LWFSTLISKQ TNLQKAYDQL EVLAPFDVRT IPMGQGNKSS
     RLIAWTFQSK EAQAKWVSAR WK
//