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Q11WL3

- Q11WL3_CYTH3

UniProt

Q11WL3 - Q11WL3_CYTH3

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Protein
Submitted name:

D-alanine--D-alanine ligase A

Gene
ddlA, CHU_0924
Organism
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Cell wall formation By similarity.SAAS annotations

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotations

Cofactori

Binds 2 magnesium or manganese ions per subunit By similarity.SAAS annotations

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
  2. regulation of cell shape Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotationsImported

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradationSAAS annotations, Peptidoglycan synthesisSAAS annotations

Keywords - Ligandi

ATP-bindingSAAS annotations, MagnesiumSAAS annotations, ManganeseSAAS annotations, Metal-bindingSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciCHUT269798:GJ83-926-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Submitted name:
D-alanine--D-alanine ligase AImported (EC:6.3.2.4Imported)
Gene namesi
Name:ddlAImported
Ordered Locus Names:CHU_0924Imported
OrganismiCytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)Imported
Taxonomic identifieri269798 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCytophagaceaeCytophaga
ProteomesiUP000001822: Chromosome

Subcellular locationi

Cytoplasm By similarity SAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmSAAS annotations

Interactioni

Protein-protein interaction databases

STRINGi269798.CHU_0924.

Structurei

3D structure databases

ProteinModelPortaliQ11WL3.

Family & Domainsi

Sequence similaritiesi

Contains ATP-grasp domain.SAAS annotations

Phylogenomic databases

eggNOGiCOG1181.
HOGENOMiHOG000121145.
KOiK01921.
OMAiGTASHEC.
OrthoDBiEOG6ND0KB.

Family and domain databases

Gene3Di3.30.1490.20. 2 hits.
3.30.470.20. 3 hits.
3.40.50.20. 2 hits.
HAMAPiMF_00047. Dala_Dala_lig.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 4 hits.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMiSSF52440. SSF52440. 2 hits.
PROSITEiPS50975. ATP_GRASP. 2 hits.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q11WL3-1 [UniParc]FASTAAdd to Basket

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MRIGIIFGGQ SREREISFAG GRTVYDNLNK DIFTTVPIFV DSLGQFILLD    50
WQYIYKGTIR DFYPPFEFLP KSIHGFQVYV ESLGDLPKEE RDAMIQKVGR 100
KIEPSDLKEL IDFAFLALHG PYGEDGAIQG MLDWNNIPYS GSGILPSAIG 150
INKYIQKKLV AQASFNGPNY VTYKKSTWLK GADTKALLAH FESSVGFPFV 200
VKAPSQGSSI GITVISERNE EKLKQALNRS FFLQEITAAD WNTKTEHAKI 250
KWVATLTDIR DGIGMPVNDV LQGKTIYHPE ELLAHLNQSL SSKERVLLES 300
LDNEEEIIIE SFIKGQEFSC IVIQDEDGNP IALPPTGIVK GNDFFDYRSK 350
YLPGMSRKIT PIDIPGEQVE LIRSECCRLY STLQFNVYAR IDGFISPEGE 400
VFLNDPNTTS GMMPSSFFFH QAAEIGLNPS QFLTYIIRTS IQERIKDGKR 450
SLRYKQLLAT LDQAISSEKN SSKEKIKIAV VMGGYSSERH ISVESGRNIF 500
EKLSSSTKYQ PLPVFLTGSD EQHRLFILPI NILLKDNADD IREKVINFKG 550
HHPIIEHIAK ETESISSRYV SNAIKDPKEI SYKELSELVD GVFIALHGRP 600
GEDGSMQKEL EKYQLPYNGS GIQSSQITIN KFETNRILRE HGISVANHRM 650
VYKQEWLDAG EKLLSEIESG FIYPIIAKPS DDGCSSAVKK IKNRDELRAY 700
TRLMFGEEAI QGSVSSSVLG LKYNEEFPQK DYFLIEDLVS KGNAKHFLEV 750
TGGLMTRFND KGNVEYEIFE PSESLATGDV LSLEEKFLAG EGQNITPARY 800
TTNKADYEQV ASEVRATLKR VAEVLNIQGY ARIDAFVRVF ENNRSETIII 850
EVNSLPGMTP ATCIFHQTAI NGYKPYDFID NILTFGIERE KKKLAKI 897
Length:897
Mass (Da):101,061
Last modified:August 22, 2006 - v1
Checksum:i74C2C50264BFB669
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000383 Genomic DNA. Translation: ABG58203.1.
RefSeqiWP_011584318.1. NC_008255.1.
YP_677543.1. NC_008255.1.

Genome annotation databases

EnsemblBacteriaiABG58203; ABG58203; CHU_0924.
GeneIDi4184112.
KEGGichu:CHU_0924.
PATRICi21592697. VBICytHut34013_0924.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000383 Genomic DNA. Translation: ABG58203.1 .
RefSeqi WP_011584318.1. NC_008255.1.
YP_677543.1. NC_008255.1.

3D structure databases

ProteinModelPortali Q11WL3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 269798.CHU_0924.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG58203 ; ABG58203 ; CHU_0924 .
GeneIDi 4184112.
KEGGi chu:CHU_0924.
PATRICi 21592697. VBICytHut34013_0924.

Phylogenomic databases

eggNOGi COG1181.
HOGENOMi HOG000121145.
KOi K01921.
OMAi GTASHEC.
OrthoDBi EOG6ND0KB.

Enzyme and pathway databases

UniPathwayi UPA00219 .
BioCyci CHUT269798:GJ83-926-MONOMER.

Family and domain databases

Gene3Di 3.30.1490.20. 2 hits.
3.30.470.20. 3 hits.
3.40.50.20. 2 hits.
HAMAPi MF_00047. Dala_Dala_lig.
InterProi IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view ]
PANTHERi PTHR23132. PTHR23132. 1 hit.
Pfami PF07478. Dala_Dala_lig_C. 4 hits.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view ]
SUPFAMi SSF52440. SSF52440. 2 hits.
PROSITEi PS50975. ATP_GRASP. 2 hits.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33406 / NCIMB 9469.

Entry informationi

Entry nameiQ11WL3_CYTH3
AccessioniPrimary (citable) accession number: Q11WL3
Entry historyi
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: September 3, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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