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Q11WL3

- Q11WL3_CYTH3

UniProt

Q11WL3 - Q11WL3_CYTH3

Protein
Submitted name:

D-alanine--D-alanine ligase A

Gene

ddlA

Organism
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (22 Aug 2006)
      Previous versions | rss
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    Functioni

    Cell wall formation.SAAS annotation

    Catalytic activityi

    ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.SAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. D-alanine-D-alanine ligase activity Source: UniProtKB-EC
    3. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
    2. regulation of cell shape Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseSAAS annotationImported

    Keywords - Biological processi

    Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

    Keywords - Ligandi

    ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCHUT269798:GJ83-926-MONOMER.
    UniPathwayiUPA00219.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    D-alanine--D-alanine ligase AImported (EC:6.3.2.4Imported)
    Gene namesi
    Name:ddlAImported
    Ordered Locus Names:CHU_0924Imported
    OrganismiCytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)Imported
    Taxonomic identifieri269798 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCytophagaceaeCytophaga
    ProteomesiUP000001822: Chromosome

    Subcellular locationi

    Cytoplasm SAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmSAAS annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi269798.CHU_0924.

    Structurei

    3D structure databases

    ProteinModelPortaliQ11WL3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains ATP-grasp domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG1181.
    HOGENOMiHOG000121145.
    KOiK01921.
    OMAiGTASHEC.
    OrthoDBiEOG6ND0KB.

    Family and domain databases

    Gene3Di3.30.1490.20. 2 hits.
    3.30.470.20. 3 hits.
    3.40.50.20. 2 hits.
    HAMAPiMF_00047. Dala_Dala_lig.
    InterProiIPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR000291. D-Ala_lig_Van_CS.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR011127. Dala_Dala_lig_N.
    IPR016185. PreATP-grasp_dom.
    [Graphical view]
    PANTHERiPTHR23132. PTHR23132. 1 hit.
    PfamiPF07478. Dala_Dala_lig_C. 4 hits.
    PF01820. Dala_Dala_lig_N. 2 hits.
    [Graphical view]
    SUPFAMiSSF52440. SSF52440. 2 hits.
    PROSITEiPS50975. ATP_GRASP. 2 hits.
    PS00843. DALA_DALA_LIGASE_1. 1 hit.
    PS00844. DALA_DALA_LIGASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q11WL3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRIGIIFGGQ SREREISFAG GRTVYDNLNK DIFTTVPIFV DSLGQFILLD    50
    WQYIYKGTIR DFYPPFEFLP KSIHGFQVYV ESLGDLPKEE RDAMIQKVGR 100
    KIEPSDLKEL IDFAFLALHG PYGEDGAIQG MLDWNNIPYS GSGILPSAIG 150
    INKYIQKKLV AQASFNGPNY VTYKKSTWLK GADTKALLAH FESSVGFPFV 200
    VKAPSQGSSI GITVISERNE EKLKQALNRS FFLQEITAAD WNTKTEHAKI 250
    KWVATLTDIR DGIGMPVNDV LQGKTIYHPE ELLAHLNQSL SSKERVLLES 300
    LDNEEEIIIE SFIKGQEFSC IVIQDEDGNP IALPPTGIVK GNDFFDYRSK 350
    YLPGMSRKIT PIDIPGEQVE LIRSECCRLY STLQFNVYAR IDGFISPEGE 400
    VFLNDPNTTS GMMPSSFFFH QAAEIGLNPS QFLTYIIRTS IQERIKDGKR 450
    SLRYKQLLAT LDQAISSEKN SSKEKIKIAV VMGGYSSERH ISVESGRNIF 500
    EKLSSSTKYQ PLPVFLTGSD EQHRLFILPI NILLKDNADD IREKVINFKG 550
    HHPIIEHIAK ETESISSRYV SNAIKDPKEI SYKELSELVD GVFIALHGRP 600
    GEDGSMQKEL EKYQLPYNGS GIQSSQITIN KFETNRILRE HGISVANHRM 650
    VYKQEWLDAG EKLLSEIESG FIYPIIAKPS DDGCSSAVKK IKNRDELRAY 700
    TRLMFGEEAI QGSVSSSVLG LKYNEEFPQK DYFLIEDLVS KGNAKHFLEV 750
    TGGLMTRFND KGNVEYEIFE PSESLATGDV LSLEEKFLAG EGQNITPARY 800
    TTNKADYEQV ASEVRATLKR VAEVLNIQGY ARIDAFVRVF ENNRSETIII 850
    EVNSLPGMTP ATCIFHQTAI NGYKPYDFID NILTFGIERE KKKLAKI 897
    Length:897
    Mass (Da):101,061
    Last modified:August 22, 2006 - v1
    Checksum:i74C2C50264BFB669
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000383 Genomic DNA. Translation: ABG58203.1.
    RefSeqiWP_011584318.1. NC_008255.1.
    YP_677543.1. NC_008255.1.

    Genome annotation databases

    EnsemblBacteriaiABG58203; ABG58203; CHU_0924.
    GeneIDi4184112.
    KEGGichu:CHU_0924.
    PATRICi21592697. VBICytHut34013_0924.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000383 Genomic DNA. Translation: ABG58203.1 .
    RefSeqi WP_011584318.1. NC_008255.1.
    YP_677543.1. NC_008255.1.

    3D structure databases

    ProteinModelPortali Q11WL3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 269798.CHU_0924.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABG58203 ; ABG58203 ; CHU_0924 .
    GeneIDi 4184112.
    KEGGi chu:CHU_0924.
    PATRICi 21592697. VBICytHut34013_0924.

    Phylogenomic databases

    eggNOGi COG1181.
    HOGENOMi HOG000121145.
    KOi K01921.
    OMAi GTASHEC.
    OrthoDBi EOG6ND0KB.

    Enzyme and pathway databases

    UniPathwayi UPA00219 .
    BioCyci CHUT269798:GJ83-926-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1490.20. 2 hits.
    3.30.470.20. 3 hits.
    3.40.50.20. 2 hits.
    HAMAPi MF_00047. Dala_Dala_lig.
    InterProi IPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR000291. D-Ala_lig_Van_CS.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR011127. Dala_Dala_lig_N.
    IPR016185. PreATP-grasp_dom.
    [Graphical view ]
    PANTHERi PTHR23132. PTHR23132. 1 hit.
    Pfami PF07478. Dala_Dala_lig_C. 4 hits.
    PF01820. Dala_Dala_lig_N. 2 hits.
    [Graphical view ]
    SUPFAMi SSF52440. SSF52440. 2 hits.
    PROSITEi PS50975. ATP_GRASP. 2 hits.
    PS00843. DALA_DALA_LIGASE_1. 1 hit.
    PS00844. DALA_DALA_LIGASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33406 / NCIMB 9469Imported.

    Entry informationi

    Entry nameiQ11WL3_CYTH3
    AccessioniPrimary (citable) accession number: Q11WL3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: August 22, 2006
    Last sequence update: August 22, 2006
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3