Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q11UX8 (Q11UX8_CYTH3) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha HAMAP MF_00823
Short name=ACCase subunit alpha HAMAP MF_00823
Short name=Acetyl-CoA carboxylase carboxyltransferase subunit alpha HAMAP MF_00823
EC=6.4.1.2 HAMAP MF_00823
Gene names
Name:accA HAMAP MF_00823
Ordered Locus Names:CHU_1517
OrganismCytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) [Complete proteome] [HAMAP] EMBL ABG58788.1
Taxonomic identifier269798 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Cytophagia › Cytophagales › Cytophagaceae › Cytophaga

Protein attributes

Sequence length317 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA By similarity. HAMAP MF_00823

Catalytic activity

ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA. HAMAP MF_00823

Pathway

Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1. HAMAP MF_00823

Subunit structure

Acetyl-CoA carboxylase is an heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD) By similarity. HAMAP MF_00823

Subcellular location

Cytoplasm By similarity HAMAP MF_00823.

Sequence similarities

Belongs to the AccA family. HAMAP MF_00823

Sequences

Sequence LengthMass (Da)Tools
Q11UX8 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: DB7302E0960D6B65

FASTA31735,517
        10         20         30         40         50         60 
MYLDFEKPIA DLETNLAEMK QVASESEVDV SSAVKALETK IKSLKKDIYG NLTRWQRVQL 

        70         80         90        100        110        120 
SRHPERPYTL DYIAGITDTF VELHGDRCVK DDLAMVGGFG EINGESFMII GQQKGRKTKE 

       130        140        150        160        170        180 
RQVRNFGMAN PDGYRKALRL MKLAEKFNRP ILTLIDTPGA YPGLEAEERG QGEAIARNLK 

       190        200        210        220        230        240 
EMFMLKVPVI CIIIGEGASG GALGIAIGDK VMMLENTWYS VISPESCSSI LFRSWDYKEQ 

       250        260        270        280        290        300 
AAEALRLTAE DMLKNKLIDD IIKEPLGGAH QDTEWMYTKM KKVIGETLAK LNQLSPAERI 

       310 
SQRIDKFSAM GVVEENA

« Hide

References

[1]"Genome sequence of the cellulolytic gliding bacterium Cytophaga hutchinsonii."
Xie G., Bruce D.C., Challacombe J.F., Chertkov O., Detter J.C., Gilna P., Han C.S., Lucas S., Misra M., Myers G.L., Richardson P., Tapia R., Thayer N., Thompson L.S., Brettin T.S., Henrissat B., Wilson D.B., McBride M.J.
Appl. Environ. Microbiol. 73:3536-3546(2007) [PubMed: 17400776] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000383 Genomic DNA. Translation: ABG58788.1.
RefSeqYP_678128.1. NC_008255.1.

3D structure databases

ProteinModelPortalQ11UX8.
SMRQ11UX8. Positions 1-312.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ11UX8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4183995.
GenomeReviewsGene locus CHU_1517 in contig CP000383_GR.
KEGGchu:CHU_1517.
NMPDRfig|269798.12.peg.1444.
PATRIC21593875. VBICytHut34013_1510.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0825.
HOGENOMHBG286557.
OMAGRDTKDN.
ProtClustDBPRK05724.

Family and domain databases

HAMAPMF_00823. AcetylCoA_CT_alpha.
[Tree]
InterProIPR001095. Acetyl_CoA_COase_a_su.
IPR011763. COA_CT_C.
[Graphical view]
KOK01962.
PANTHERPTHR22855:SF3. Ac-CoA_carboxylA. 1 hit.
PfamPF03255. ACCA. 1 hit.
[Graphical view]
PRINTSPR01069. ACCCTRFRASEA.
TIGRFAMsTIGR00513. AccA. 1 hit.
PROSITEPS50989. COA_CT_CTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ11UX8_CYTH3
AccessionPrimary (citable) accession number: Q11UX8
Entry history
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info