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Protein

Glutaminase

Gene

glsA

Organism
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei63SubstrateUniRule annotation1
Binding sitei113SubstrateUniRule annotation1
Binding sitei157SubstrateUniRule annotation1
Binding sitei164SubstrateUniRule annotation1
Binding sitei188SubstrateUniRule annotation1
Binding sitei240SubstrateUniRule annotation1
Binding sitei258Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:CHU_1741
OrganismiCytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Taxonomic identifieri269798 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCytophagaceaeCytophaga
Proteomesi
  • UP000001822 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003360261 – 304GlutaminaseAdd BLAST304

Proteomic databases

PRIDEiQ11UA6.

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi269798.CHU_1741.

Structurei

3D structure databases

ProteinModelPortaliQ11UA6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiANYMKSF.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q11UA6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNYQAILNQI QGDIQPYLGQ GKVADYIPAL AGINPSKFGM SIHTIDGITA
60 70 80 90 100
TIGDAQEQFS IQSISKILTL TMAVSLDDTN IWKRVGREPS GSKFNSLIQL
110 120 130 140 150
ELEQGIPRNP FINAGAHVIT DLVYSHFDDP KEAILAFTRM VSMNDSISYD
160 170 180 190 200
YVVAQSERET GNRNLAMGYF MKSFGNIENK VRDVLDVYFH QCSLAMSCTD
210 220 230 240 250
LSKAFLYLAN EGVLPTSEKT IITKKNSDRI NALMLTCGMY DSVGDFAYRV
260 270 280 290 300
GLPSKSGVGG GIVSIVPGEM VIAVWSPGLS ESGNSLAGTK ALELFVNYTG

KTIF
Length:304
Mass (Da):33,129
Last modified:August 22, 2006 - v1
Checksum:iB8F9D2F6D621EC0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000383 Genomic DNA. Translation: ABG59008.1.
RefSeqiWP_011585125.1. NC_008255.1.

Genome annotation databases

EnsemblBacteriaiABG59008; ABG59008; CHU_1741.
KEGGichu:CHU_1741.
PATRICi21594329. VBICytHut34013_1730.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000383 Genomic DNA. Translation: ABG59008.1.
RefSeqiWP_011585125.1. NC_008255.1.

3D structure databases

ProteinModelPortaliQ11UA6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi269798.CHU_1741.

Proteomic databases

PRIDEiQ11UA6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG59008; ABG59008; CHU_1741.
KEGGichu:CHU_1741.
PATRICi21594329. VBICytHut34013_1730.

Phylogenomic databases

eggNOGiENOG4105CSV. Bacteria.
COG2066. LUCA.
HOGENOMiHOG000216890.
KOiK01425.
OMAiANYMKSF.
OrthoDBiPOG091H02PU.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLSA_CYTH3
AccessioniPrimary (citable) accession number: Q11UA6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 22, 2006
Last modified: November 2, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.