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Q11UA6 (GLSA_CYTH3) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:CHU_1741
OrganismCytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) [Complete proteome] [HAMAP]
Taxonomic identifier269798 [NCBI]
Taxonomic lineageBacteriaBacteroidetesCytophagiaCytophagalesCytophagaceaeCytophaga

Protein attributes

Sequence length304 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 304304Glutaminase HAMAP-Rule MF_00313
PRO_0000336026

Sites

Binding site631Substrate By similarity
Binding site1131Substrate By similarity
Binding site1571Substrate By similarity
Binding site1641Substrate By similarity
Binding site1881Substrate By similarity
Binding site2401Substrate By similarity
Binding site2581Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q11UA6 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: B8F9D2F6D621EC0B

FASTA30433,129
        10         20         30         40         50         60 
MNYQAILNQI QGDIQPYLGQ GKVADYIPAL AGINPSKFGM SIHTIDGITA TIGDAQEQFS 

        70         80         90        100        110        120 
IQSISKILTL TMAVSLDDTN IWKRVGREPS GSKFNSLIQL ELEQGIPRNP FINAGAHVIT 

       130        140        150        160        170        180 
DLVYSHFDDP KEAILAFTRM VSMNDSISYD YVVAQSERET GNRNLAMGYF MKSFGNIENK 

       190        200        210        220        230        240 
VRDVLDVYFH QCSLAMSCTD LSKAFLYLAN EGVLPTSEKT IITKKNSDRI NALMLTCGMY 

       250        260        270        280        290        300 
DSVGDFAYRV GLPSKSGVGG GIVSIVPGEM VIAVWSPGLS ESGNSLAGTK ALELFVNYTG 


KTIF 

« Hide

References

[1]"Genome sequence of the cellulolytic gliding bacterium Cytophaga hutchinsonii."
Xie G., Bruce D.C., Challacombe J.F., Chertkov O., Detter J.C., Gilna P., Han C.S., Lucas S., Misra M., Myers G.L., Richardson P., Tapia R., Thayer N., Thompson L.S., Brettin T.S., Henrissat B., Wilson D.B., McBride M.J.
Appl. Environ. Microbiol. 73:3536-3546(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33406 / NCIMB 9469.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000383 Genomic DNA. Translation: ABG59008.1.
RefSeqYP_678350.1. NC_008255.1.

3D structure databases

ProteinModelPortalQ11UA6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING269798.CHU_1741.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABG59008; ABG59008; CHU_1741.
GeneID4183922.
KEGGchu:CHU_1741.
PATRIC21594329. VBICytHut34013_1730.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMASLANERN.
OrthoDBEOG6N94BK.

Enzyme and pathway databases

BioCycCHUT269798:GJ83-1744-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_CYTH3
AccessionPrimary (citable) accession number: Q11UA6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 22, 2006
Last modified: May 14, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families