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Q11UA6

- GLSA_CYTH3

UniProt

Q11UA6 - GLSA_CYTH3

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Protein

Glutaminase

Gene
glsA, CHU_1741
Organism
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei63 – 631Substrate By similarity
Binding sitei113 – 1131Substrate By similarity
Binding sitei157 – 1571Substrate By similarity
Binding sitei164 – 1641Substrate By similarity
Binding sitei188 – 1881Substrate By similarity
Binding sitei240 – 2401Substrate By similarity
Binding sitei258 – 2581Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciCHUT269798:GJ83-1744-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:CHU_1741
OrganismiCytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Taxonomic identifieri269798 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCytophagaceaeCytophaga
ProteomesiUP000001822: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304GlutaminaseUniRule annotationPRO_0000336026Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi269798.CHU_1741.

Structurei

3D structure databases

ProteinModelPortaliQ11UA6.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiSLANERN.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q11UA6-1 [UniParc]FASTAAdd to Basket

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MNYQAILNQI QGDIQPYLGQ GKVADYIPAL AGINPSKFGM SIHTIDGITA    50
TIGDAQEQFS IQSISKILTL TMAVSLDDTN IWKRVGREPS GSKFNSLIQL 100
ELEQGIPRNP FINAGAHVIT DLVYSHFDDP KEAILAFTRM VSMNDSISYD 150
YVVAQSERET GNRNLAMGYF MKSFGNIENK VRDVLDVYFH QCSLAMSCTD 200
LSKAFLYLAN EGVLPTSEKT IITKKNSDRI NALMLTCGMY DSVGDFAYRV 250
GLPSKSGVGG GIVSIVPGEM VIAVWSPGLS ESGNSLAGTK ALELFVNYTG 300
KTIF 304
Length:304
Mass (Da):33,129
Last modified:August 22, 2006 - v1
Checksum:iB8F9D2F6D621EC0B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000383 Genomic DNA. Translation: ABG59008.1.
RefSeqiWP_011585125.1. NC_008255.1.
YP_678350.1. NC_008255.1.

Genome annotation databases

EnsemblBacteriaiABG59008; ABG59008; CHU_1741.
GeneIDi4183922.
KEGGichu:CHU_1741.
PATRICi21594329. VBICytHut34013_1730.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000383 Genomic DNA. Translation: ABG59008.1 .
RefSeqi WP_011585125.1. NC_008255.1.
YP_678350.1. NC_008255.1.

3D structure databases

ProteinModelPortali Q11UA6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 269798.CHU_1741.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG59008 ; ABG59008 ; CHU_1741 .
GeneIDi 4183922.
KEGGi chu:CHU_1741.
PATRICi 21594329. VBICytHut34013_1730.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi SLANERN.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci CHUT269798:GJ83-1744-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33406 / NCIMB 9469.

Entry informationi

Entry nameiGLSA_CYTH3
AccessioniPrimary (citable) accession number: Q11UA6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: August 22, 2006
Last modified: September 3, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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