Reviewed,
UniProtKB/Swiss-Prot Q11QU6 (BIOD_CYTH3)
Last modified
May 5, 2009.
Version 20.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Dethiobiotin synthetase EC=6.3.3.3 Alternative name(s): Dethiobiotin synthase DTB synthetase Short name=DTBS | ||||
| Gene names |
| ||||
| Organism | Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 269798 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Bacteroidetes › Sphingobacteria › Sphingobacteriales › Flexibacteraceae › Cytophaga |
Protein attributes
| Sequence length | 206 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin. HAMAP MF_00336 |
| Cofactor | Magnesium By similarity. |
| Pathway | Cofactor biosynthesis; biotin biosynthesis; biotin from 6-carboxyhexanoyl-CoA: step 3/4. HAMAP MF_00336 |
| Sequence similarities | Belongs to the dethiobiotin synthetase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Biotin biosynthesis |
| Ligand | ATP-binding Magnesium Nucleotide-binding |
| Molecular function | Ligase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | biotin biosynthetic process Inferred from electronic annotation. Source: HAMAP |
| Molecular function | ATP binding Inferred from electronic annotation. Source: HAMAP dethiobiotin synthase activityInferred from electronic annotation. Source: HAMAP magnesium ion bindingInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 206 | 206 | Dethiobiotin synthetase HAMAP MF_00336 | PRO_0000302504 | |||||
Regions | |||||||||
| Nucleotide binding | 8 – 16 | 9 | ATP By similarity | ||||||
Sequences
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References
| [1] | "Genome sequence of the cellulolytic gliding bacterium Cytophaga hutchinsonii." Xie G., Bruce D.C., Challacombe J.F., Chertkov O., Detter J.C., Gilna P., Han C.S., Lucas S., Misra M., Myers G.L., Richardson P., Tapia R., Thayer N., Thompson L.S., Brettin T.S., Henrissat B., Wilson D.B., McBride M.J. Appl. Environ. Microbiol. 73:3536-3546(2007) [PubMed: 17400776] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| CP000383 Genomic DNA. Translation: ABG60218.1. | |
| RefSeq | YP_679560.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 4185086. |
| GenomeReviews | Gene locus CHU_2977 in contig CP000383_GR. |
| KEGG | chu:CHU_2977. |
| NMPDR | fig|269798.12.peg.2842. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q11QU6. |
| OMA | Q11QU6. SPHWAAE. |
Enzyme and pathway databases | |
| BioCyc | CHUT269798:CHU_2977-MON. |
Family and domain databases | |
| HAMAP | MF_00336. [Tree] |
| InterPro | IPR004472. BioD_synth. [Graphical view] |
| PIRSF | PIRSF006755. DTB_synth. 1 hit. |
| TIGRFAMs | TIGR00347. bioD. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | BIOD_CYTH3 | ||||||||
| Accession | Primary (citable) accession number: Q11QU6 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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