Q11QR5 (Q11QR5_CYTH3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Chromosomal replication initiator protein DnaA HAMAP MF_00377

Gene names

Name:	dnaA HAMAP MF_00377
Ordered Locus Names:	CHU_3008

Organism

Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) [Complete proteome] [HAMAP] EMBL ABG60249.1

Taxonomic identifier

269798 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Cytophagia › Cytophagales › Cytophagaceae › Cytophaga

Protein attributes

Sequence length	471 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids By similarity. HAMAP MF_00377
Subcellular location	Cytoplasm By similarity HAMAP MF_00377.
Sequence similarities	Belongs to the DnaA family. HAMAP MF_00377

Ontologies

Keywords
Biological process	DNA replication HAMAP MF_00377
Cellular component	Cytoplasm HAMAP MF_00377
Ligand	ATP-binding HAMAP MF_00377 DNA-binding HAMAP MF_00377 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA-dependent DNA replication initiation Inferred from electronic annotation. Source: HAMAP regulation of DNA replication Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA replication origin binding Inferred from electronic annotation. Source: HAMAP nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	173 – 180	8	ATP By similarity HAMAP MF_00377

Sequences

	Sequence		Length	Mass (Da)
	Q11QR5 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: AC0F1ABC3C010093	FASTA	471	53,677
	10 20 30 40 50 60 MIDVRDCKSV WNSCLEYIRQ CVGDQSFKTW FEPVEPLMLV NNVLTIQVPS QFFYEWLEEH 70 80 90 100 110 120 YVHVLRKAID EQLGPDGRLE YQILVDKNDL NRKSYGTTLH KGSIISRSIN PGVSKETKQE 130 140 150 160 170 180 VPAVSQPIDS QLNASYSFDT FIEGDCNKLA RSAGLAVANK PGVTSFNPLL VYGNVGLGKT 190 200 210 220 230 240 HLVQAIGNQI KKNHADKKVL YMPSERFLSQ FIEAMKNNQS QEFTNQFLGL DVLILDDVQF 250 260 270 280 290 300 LSGKEKTQEI FFHIFNHLHQ SGKQIIITSD CAPKDIKGLQ ERLLSRFKWG LSADLQVPDY 310 320 330 340 350 360 ETRNAIICKK MQFEGIEIAA DVIDYLAYSV DTNMRDLEGV VNSLIAQHTL SGRQIDLELA 370 380 390 400 410 420 KQIIQNIVQN VETEVNIDYI QKFVSEYFAV TIEQMKDKTR KREIVIARQV AMYFTKEYTN 430 440 450 460 470 MSLKSIGNHF GGRDHSTVIH ALTSVSDLMD TDKKFRATMQ DLIKKIKIKS A

References

[1]

"Genome sequence of the cellulolytic gliding bacterium Cytophaga hutchinsonii." Xie G., Bruce D.C., Challacombe J.F., Chertkov O., Detter J.C., Gilna P., Han C.S., Lucas S., Misra M., Myers G.L., Richardson P., Tapia R., Thayer N., Thompson L.S., Brettin T.S., Henrissat B., Wilson D.B., McBride M.J. Appl. Environ. Microbiol. 73:3536-3546(2007) [PubMed: 17400776] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000383 Genomic DNA. Translation: ABG60249.1.
RefSeq	YP_679591.1. NC_008255.1.
3D structure databases
ProteinModelPortal	Q11QR5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q11QR5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4183741.
GenomeReviews	Gene locus CHU_3008 in contig CP000383_GR.
KEGG	chu:CHU_3008.
NMPDR	fig|269798.12.peg.2874.
PATRIC	21596883. VBICytHut34013_2991.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0593.
HOGENOM	HBG695666.
OMA	CHTLNAL.
ProtClustDB	PRK00149.
Family and domain databases
HAMAP	MF_00377. DnaA_bact. [Tree]
InterPro	IPR003593. ATPase_AAA+_core. IPR001957. Chromosome_initiator_DnaA. IPR020591. Chromosome_initiator_DnaA-like. IPR018312. Chromosome_initiator_DnaA_CS. IPR013159. DnaA_C. IPR013317. DnaA_Hda. IPR010921. Trp_repressor/repl_initiator. [Graphical view]
Gene3D	G3DSA:1.10.1750.10. DnaA_C. 1 hit.
KO	K02313.
Pfam	PF00308. Bac_DnaA. 1 hit. PF08299. Bac_DnaA_C. 1 hit. [Graphical view]
PRINTS	PR00051. DNAA.
SMART	SM00382. AAA. 1 hit. SM00760. Bac_DnaA_C. 1 hit. [Graphical view]
SUPFAM	SSF48295. Trp_repress_rep. 1 hit.
TIGRFAMs	TIGR00362. DnaA. 1 hit.
PROSITE	PS01008. DNAA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q11QR5_CYTH3

Accession

Primary (citable) accession number: Q11QR5

Entry history

Integrated into UniProtKB/TrEMBL:	August 22, 2006
Last sequence update:	August 22, 2006
Last modified:	December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)