ID   PHS_CYTH3               Reviewed;         103 AA.
AC   Q11PN9;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   05-MAY-2009, entry version 20.
DE   RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase;
DE            Short=PHS;
DE            EC=4.2.1.96;
DE   AltName: Full=4-alpha-hydroxy-tetrahydropterin dehydratase;
DE   AltName: Full=Pterin carbinolamine dehydratase;
DE            Short=PCD;
GN   OrderedLocusNames=CHU_3388;
OS   Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469).
OC   Bacteria; Bacteroidetes; Sphingobacteria; Sphingobacteriales;
OC   Flexibacteraceae; Cytophaga.
OX   NCBI_TaxID=269798;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17400776; DOI=10.1128/AEM.00225-07;
RA   Xie G., Bruce D.C., Challacombe J.F., Chertkov O., Detter J.C.,
RA   Gilna P., Han C.S., Lucas S., Misra M., Myers G.L., Richardson P.,
RA   Tapia R., Thayer N., Thompson L.S., Brettin T.S., Henrissat B.,
RA   Wilson D.B., McBride M.J.;
RT   "Genome sequence of the cellulolytic gliding bacterium Cytophaga
RT   hutchinsonii.";
RL   Appl. Environ. Microbiol. 73:3536-3546(2007).
CC   -!- CATALYTIC ACTIVITY: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-
CC       5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-
CC       dihydroxypropyl)-7,8-dihydro-6H-pterin + H(2)O.
CC   -!- SIMILARITY: Belongs to the pterin-4-alpha-carbinolamine
CC       dehydratase family.
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DR   EMBL; CP000383; ABG60624.1; -; Genomic_DNA.
DR   RefSeq; YP_679967.1; -.
DR   GeneID; 4187177; -.
DR   GenomeReviews; CP000383_GR; CHU_3388.
DR   KEGG; chu:CHU_3388; -.
DR   HOGENOM; Q11PN9; -.
DR   OMA; Q11PN9; DWEEREN.
DR   BioCyc; CHUT269798:CHU_3388-MON; -.
DR   GO; GO:0008124; F:4-alpha-hydroxytetrahydrobiopterin dehydrat...; IEA:HAMAP.
DR   GO; GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_00434; -; 1.
DR   InterPro; IPR001533; Trans/pterin_deHydtase.
DR   Gene3D; G3DSA:3.30.1360.20; Trans_pterinDh; 1.
DR   PANTHER; PTHR12599; Trans_pterinDh; 1.
DR   Pfam; PF01329; Pterin_4a; 1.
DR   ProDom; PD007262; Trans_pterinDh; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Lyase.
FT   CHAIN         1    103       Putative pterin-4-alpha-carbinolamine
FT                                dehydratase.
FT                                /FTId=PRO_1000050415.
SQ   SEQUENCE   103 AA;  12171 MW;  FEAAB830A02471E7 CRC64;
     MYVLVNKNPC NSLFKLFLFI MNKWTEQNNR LIKQFQFKDF KEAFEFMKRV AVVADKMDHH
     PYWTNCYNKV YIELNTHSAG GVVTKKDFSL AEAIDTLAHE SDN
//