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Q11PE0 (Q11PE0_CYTH3) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:CHU_3490
OrganismCytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) [Complete proteome] [HAMAP] EMBL ABG60723.1
Taxonomic identifier269798 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Cytophagia › Cytophagales › Cytophagaceae › Cytophaga

Protein attributes

Sequence length344 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323

Ontologies

Keywords
   Biological processHeme biosynthesis HAMAP MF_00323
Porphyrin biosynthesis HAMAP MF_00323
   Cellular componentCytoplasm HAMAP MF_00323
   LigandIron HAMAP MF_00323
Metal-binding HAMAP MF_00323
   Molecular functionLyase HAMAP MF_00323 EMBL ABG60723.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processheme biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionferrochelatase activity

Inferred from electronic annotation. Source: HAMAP

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1981Iron By similarity HAMAP MF_00323
Metal binding2991Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
Q11PE0 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: E271BA2CF7BA679B

FASTA34439,237
        10         20         30         40         50         60 
MALPNKKSKT AVFLINLGTP DSPNTPDVRK YLRQFLMDRR VIDIPWLNRW LLINMIIAPF 

        70         80         90        100        110        120 
RAPKSAHEYK KLWTEQGSPL MFHGVAVKEL LQQALGDEYK VVLGMRYQNP SIESAAKELE 

       130        140        150        160        170        180 
AKGYNKVIVV PLFPQYASAS TGSAVEEALR VLGKWEITPH IEVISKFFDH PLFIKAFAEI 

       190        200        210        220        230        240 
GRKYLAERNW DHIIFSYHGI PERQIKKASI GDQCKLGTCC QVYGSRNEYC YRAQCYETTR 

       250        260        270        280        290        300 
LLVKELGLAE GSYSVSFQSR LGKTPWIKPY TDHNIEELGK AGKKSILFFS PSFIADCLET 

       310        320        330        340 
TVEGGEEYKL LFEEHGGKDW QLVESLNTNP TWVECLKDMV VSKS

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References

[1]"Genome sequence of the cellulolytic gliding bacterium Cytophaga hutchinsonii."
Xie G., Bruce D.C., Challacombe J.F., Chertkov O., Detter J.C., Gilna P., Han C.S., Lucas S., Misra M., Myers G.L., Richardson P., Tapia R., Thayer N., Thompson L.S., Brettin T.S., Henrissat B., Wilson D.B., McBride M.J.
Appl. Environ. Microbiol. 73:3536-3546(2007) [PubMed: 17400776] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000383 Genomic DNA. Translation: ABG60723.1.
RefSeqYP_680066.1. NC_008255.1.

3D structure databases

ProteinModelPortalQ11PE0.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ11PE0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4183884.
GenomeReviewsGene locus CHU_3490 in contig CP000383_GR.
KEGGchu:CHU_3490.
NMPDRfig|269798.12.peg.3326.
PATRIC21597851. VBICytHut34013_3470.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMAIRPAKSA.
ProtClustDBPRK00035.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ11PE0_CYTH3
AccessionPrimary (citable) accession number: Q11PE0
Entry history
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info