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Q11K51 (Q11K51_MESSB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable L-aspartate dehydrogenase HAMAP MF_01265
EC=1.4.1.21 HAMAP MF_01265
Gene names
Name:nadX HAMAP MF_01265
Ordered Locus Names:Meso_0824
OrganismMesorhizobium sp. (strain BNC1) [Complete proteome] [HAMAP]
Taxonomic identifier266779 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Chelativorans

Protein attributes

Sequence length270 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate By similarity. HAMAP MF_01265

Catalytic activity

L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H. HAMAP MF_01265

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. HAMAP MF_01265

Miscellaneous

The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia By similarity. HAMAP MF_01265

Sequence similarities

Belongs to the L-aspartate dehydrogenase family. HAMAP MF_01265

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2231 By similarity HAMAP MF_01265
Binding site1271NAD; via amide nitrogen By similarity HAMAP MF_01265
Binding site1931NAD By similarity HAMAP MF_01265

Sequences

Sequence LengthMass (Da)Tools
Q11K51 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: 3D7510D3990041BF

FASTA27028,412
        10         20         30         40         50         60 
MHLGLIGYGN IARTLMGILS RESVPLSQVT VVCPRGFADE SRVRLASDFA GPGTVVCETQ 

        70         80         90        100        110        120 
ALVEAAPDLV VECAGHEGVR QHATAVLQAG IETIIVSIGS LADRSLHEAV IQAARAGSSR 

       130        140        150        160        170        180 
FILPAGAIGG IDILSALKVS GIEAVTYTGR KPPHAWKDTP AAALYDLDTL ATETVFFSGN 

       190        200        210        220        230        240 
AREAATQYPK NANVAATLAL AGLGFEKTDV RLIADPAAKG NVHEYSVRSA AADFTMKIEG 

       250        260        270 
RPSPDNPKTS VTTVYSIARE VFNRCREQAI

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References

[1]"Complete sequence of chromosome of Mesorhizobium sp. BNC1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.
Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BNC1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000390 Genomic DNA. Translation: ABG62224.1.
RefSeqYP_673389.1. NC_008254.1.

3D structure databases

ProteinModelPortalQ11K51.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ11K51.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4181084.
GenomeReviewsGene locus Meso_0824 in contig CP000390_GR.
KEGGmes:Meso_0824.
NMPDRfig|266779.1.peg.4261.
PATRIC21341570. VBICheSp72577_1429.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1712.
HOGENOMHBG649642.
OMAECAGHSA.

Family and domain databases

HAMAPMF_01265. NadX.
[Tree]
InterProIPR005106. Asp/hSer_DH_NAD-bd.
IPR002811. Asp_DH.
IPR011182. Asp_DH_NAD_syn.
IPR020626. Asp_DH_NAD_syn_prok.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK06989.
PfamPF01958. DUF108. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFPIRSF005227. Asp_dh_NAD_syn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ11K51_MESSB
AccessionPrimary (citable) accession number: Q11K51
Entry history
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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