Reviewed, UniProtKB/Swiss-Prot Q11JE6 (ADEC_MESSB)

Names and origin

Protein names

Recommended name:
    Adenine deaminase
      Short name=Adenase
      Short name=Adenine aminase
    EC=3.5.4.2

Gene names

Name:	ade
Ordered Locus Names:	Meso_1082

Organism

Mesorhizobium sp. (strain BNC1) [Complete proteome] [HAMAP]

Taxonomic identifier

266779 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Mesorhizobium

Protein attributes

Sequence length	600 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Adenine + H2O = hypoxanthine + NH3. HAMAP MF_01518
Cofactor	Manganese By similarity.
Sequence similarities	Belongs to the adenine deaminase family.

Ontologies

Keywords
Ligand	Manganese
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	adenine deaminase activity Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 600	600	Adenine deaminase HAMAP MF_01518		PRO_0000296728

Sequences

	Sequence		Length	Mass (Da)
	Q11JE6-1 [UniParc]. Last modified August 22, 2006. Version 1. Checksum: 1569B9FAD02D1C05	FASTA	600	64,391
	10 20 30 40 50 60 MSTLTRFSVR PLATMTRHLA DVASGRAEPD LVIKGARVLS TYSERILPDR EVWISGGRIA 70 80 90 100 110 120 AVKPAGSYRG SAATIYDAAG GLIAPGLVDP HIHIESSMVT ACSYAEAALL NGTTTIFCDS 130 140 150 160 170 180 HEIGNVMDVA GVEAMLEDAR QAPSSIFLTV PSTVPATSPE LETAGGDLTA EKIAALFDKW 190 200 210 220 230 240 PEAVALGEKM DFVQVAMGDE RSHAILAAAL ERGRPVSGHV YGREFVAAYA ASGVTDTHEA 250 260 270 280 290 300 IDREIADDLL EAGIWLFLRG GPPTTPWHSL PQAIKTITEL GASHKRIAVC TDDRDADDLL 310 320 330 340 350 360 LFGLDWVTRE AMKAGMKPEQ AWAMGSLHGA TRFGLEGDIG GLGGGRRADL VLLDDGFKPV 370 380 390 400 410 420 NTWYGGELVV ENRKITPLLD TALSNRYRYP EAAYHTVKLP KAVKLTPELP TARVVAHTIR 430 440 450 460 470 480 TELPGITLGH ERITLEPSNH WQDHFDRHGL CFVAVVERHG KSAGNVAHGL LSNFNLKRGA 490 500 510 520 530 540 VASSVGHDSH NIIVAGTNEA DMQVALRAIE EAQGGVCVVM DGKVTAMVPL PIAGLLSDKR 550 560 570 580 590 600 VTEVAEEVKA LKVEWEKAGC SIPYMGFNLI PLSVIPEIRI TDKGLVLVPE MEIVQLFEAA

References

[1]

"Complete sequence of chromosome of Mesorhizobium sp. BNC1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P. Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000390 Genomic DNA. Translation: ABG62479.1.
RefSeq	YP_673644.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4181242.
GenomeReviews	Gene locus Meso_1082 in contig CP000390_GR.
KEGG	mes:Meso_1082.
NMPDR	fig|266779.1.peg.2499.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q11JE6.
OMA	Q11JE6. DSHEIGN.
Enzyme and pathway databases
BioCyc	MSP266779:MESO_1082-MON.
Family and domain databases
HAMAP	MF_01518. [Tree]
InterPro	IPR006680. Amidohydro_1. [Graphical view]
Pfam	PF01979. Amidohydro_1. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ADEC_MESSB

Accession

Primary (citable) accession number: Q11JE6

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 24, 2007
Last sequence update:	August 22, 2006
Last modified:	June 16, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)