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Q11HJ2 (PNCB_CHESB) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:Meso_1739
OrganismChelativorans sp. (strain BNC1) [Complete proteome] [HAMAP]
Taxonomic identifier266779 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeChelativorans

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 434434Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000146843

Sequences

Sequence LengthMass (Da)Tools
Q11HJ2 [UniParc].

Last modified August 22, 2006. Version 1.
Checksum: 5B36D2848B3F2D3E

FASTA43450,295
        10         20         30         40         50         60 
MTVTDIARRV YNHTWKLDPI CRSLLDTDFY KLLMLQMIWG LYQDVDATFS LTNRNHRVRL 

        70         80         90        100        110        120 
ADEIDEAELR AQLDHARTIR FSKKEMIWLA GNSFYGRKQI FSPEFLAWLA DFQLPEYELR 

       130        140        150        160        170        180 
RRDGQFELHF YGRWMETTMW EIPALAIINE LRSRAAMRTL GRFALDVLYA RAKAKVWEKV 

       190        200        210        220        230        240 
ERLKKYPDIR ISDFGTRRRH SFLWQRWCVE ALKEGIGESF TGTSNVLLAM DTDLEALGTN 

       250        260        270        280        290        300 
AHELPMVLAA LSSSDEELKA SPYQVLKDWQ SYYGGNLLIV LPDTFGTESF LEDAPGWVAD 

       310        320        330        340        350        360 
WTGFRPDSAP PIEGGERIIS WWEQHGRDPR EKLLIFSDAL DVDTIEQTYR HFKGRSRLSF 

       370        380        390        400        410        420 
GWGTNLTNDF DGCAPEKIDR LKAISLVCKV SSANGRPAVK LSDNPEKATG RPEEIQRYLR 

       430 
VFGSRNRVHQ PVEV 

« Hide

References

[1]"Complete sequence of chromosome of Mesorhizobium sp. BNC1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.
Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BNC1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000390 Genomic DNA. Translation: ABG63133.1.
RefSeqYP_674298.1. NC_008254.1.

3D structure databases

ProteinModelPortalQ11HJ2.
SMRQ11HJ2. Positions 1-426.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING266779.Meso_1739.

Proteomic databases

PRIDEQ11HJ2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABG63133; ABG63133; Meso_1739.
GeneID4182502.
KEGGmes:Meso_1739.
PATRIC21343534. VBICheSp72577_2395.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284929.
KOK00763.
OMAQAVFHRY.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycCSP266779:GI09-1766-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERPTHR11098:SF1. PTHR11098:SF1. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_CHESB
AccessionPrimary (citable) accession number: Q11HJ2
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: August 22, 2006
Last modified: June 11, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways