Reviewed, UniProtKB/Swiss-Prot Q11CK5 (COAA_MESSB)

Names and origin

Protein names

Recommended name:
    Pantothenate kinase
    EC=2.7.1.33
Alternative name(s):
    Pantothenic acid kinase

Gene names

Name:	coaA
Ordered Locus Names:	Meso_3499

Organism

Mesorhizobium sp. (strain BNC1) [Complete proteome] [HAMAP]

Taxonomic identifier

266779 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Mesorhizobium

Protein attributes

Sequence length	319 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate. HAMAP MF_00215
Pathway	Cofactor biosynthesis; coenzyme A biosynthesis; coenzyme A from pantothenate: step 1/5. HAMAP MF_00215
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the prokaryotic pantothenate kinase family.

Ontologies

Keywords
Biological process	Coenzyme A biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme A biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP pantothenate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 319	319	Pantothenate kinase HAMAP MF_00215		PRO_0000325556
Regions
	Nucleotide binding	97 – 104	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q11CK5-1 [UniParc]. Last modified March 18, 2008. Version 2. Checksum: 8D20A9B873BD120B	FASTA	319	36,707
	10 20 30 40 50 60 MDQLVPAERY SPYRFFSAED WAKFRADTPL TLTEDEVRRL RSLNDPVNLE EVRRIYLSMS 70 80 90 100 110 120 RLLSAHVEAS QLLFQQRQVF FDSDHAVKTP FIIGIAGSVA VGKSTTARVL KELLTRWPSS 130 140 150 160 170 180 PKVDLITTDG FLLPNAVLSH EGLMERKGFP ESYDVGAILR FLSGIKAGLP NMRAPIYSHL 190 200 210 220 230 240 TYDVVPGEFA VIDRPDILIF EGINVLQTRD LPRDGKAVPF VSDFFDFSIY IDAPEELIHE 250 260 270 280 290 300 WYVDRFMRLR ETAFRDPNSF FHRYSTLPEV EARTIAEELW TNINLKNLRE NILPTRPRAD 310 LILRKGTNHL VQEVALRKL

References

[1]

"Complete sequence of chromosome of Mesorhizobium sp. BNC1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P. Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000390 Genomic DNA. Translation: ABG64870.1. Different initiation.
RefSeq	YP_676035.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4182159.
GenomeReviews	Gene locus Meso_3499 in contig CP000390_GR.
KEGG	mes:Meso_3499.
NMPDR	fig|266779.1.peg.1035.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q11CK5.
Enzyme and pathway databases
BioCyc	MSP266779:MESO_3499-MON.
Family and domain databases
HAMAP	MF_00215. [Tree]
InterPro	IPR004566. PanK_bact. [Graphical view]
PANTHER	PTHR10285:SF7. PanK_bact. 1 hit.
PIRSF	PIRSF000545. Pantothenate_kin. 1 hit.
TIGRFAMs	TIGR00554. panK_bact. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COAA_MESSB

Accession

Primary (citable) accession number: Q11CK5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	March 18, 2008
Last modified:	June 16, 2009
This is version 21 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)