ID   ADD_MESSB               Reviewed;         325 AA.
AC   Q11C48;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   05-MAY-2009, entry version 19.
DE   RecName: Full=Adenosine deaminase;
DE            EC=3.5.4.4;
DE   AltName: Full=Adenosine aminohydrolase;
GN   Name=add; OrderedLocusNames=Meso_3659;
OS   Mesorhizobium sp. (strain BNC1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Phyllobacteriaceae; Mesorhizobium.
OX   NCBI_TaxID=266779;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R.,
RA   Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Richardson P.;
RT   "Complete sequence of chromosome of Mesorhizobium sp. BNC1.";
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Adenosine + H(2)O = inosine + NH(3).
CC   -!- SIMILARITY: Belongs to the adenosine and AMP deaminases family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000390; ABG65027.1; -; Genomic_DNA.
DR   RefSeq; YP_676192.1; -.
DR   GeneID; 4179536; -.
DR   GenomeReviews; CP000390_GR; Meso_3659.
DR   KEGG; mes:Meso_3659; -.
DR   NMPDR; fig|266779.1.peg.878; -.
DR   HOGENOM; Q11C48; -.
DR   OMA; Q11C48; DPPFFHT.
DR   BioCyc; MSP266779:MESO_3659-MON; -.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:HAMAP.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynt...; IEA:HAMAP.
DR   HAMAP; MF_00540; -; 1.
DR   InterPro; IPR006650; A/AMP_deam_AS.
DR   InterPro; IPR001365; A/AMP_deaminase.
DR   InterPro; IPR006330; A_deaminase.
DR   PANTHER; PTHR11409; A/AMP_deaminase; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   TIGRFAMs; TIGR01430; aden_deam; 1.
DR   PROSITE; PS00485; A_DEAMINASE; FALSE_NEG.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Nucleotide metabolism.
FT   CHAIN         1    325       Adenosine deaminase.
FT                                /FTId=PRO_1000017666.
FT   ACT_SITE    186    186       Potential.
FT   ACT_SITE    234    234       Potential.
FT   ACT_SITE    267    267       Potential.
FT   ACT_SITE    268    268       Potential.
SQ   SEQUENCE   325 AA;  35034 MW;  58A2E1806AE4B0B3 CRC64;
     MLLKAELHCH IEGAASPALV KAQARKYGAD ISSFIRGGAY YWQDFTTFLL AYDQAASLFR
     TQEDYALLAE TYLKELAAGG AIYSEFFTSP DHAERAGLSP QAYTDGLAEG MVQAKAATGI
     ESRMIVTGVR HFGPEAVEKA ARFAASCEHP LVTGFGMAGD ERAGHPRDFA YAFDIAREAG
     LGISIHAGEF GGAESVEAAL DHIRPSRIGH GVRAIENPDL VRRIADEGVV LEVCPVSNVV
     LKVFPEFARH PFPQLVAAGC RVTLNSDDPP HFHTSLAREY AVAAEYFGLD ETTLNAITST
     AIEAAFVDEK TRAALFARLK PVVES
//