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Protein

Putative thymidine phosphorylase

Gene

Meso_3880

Organism
Chelativorans sp. (strain BNC1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

  1. phosphorylase activity Source: InterPro
  2. thymidine phosphorylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pyrimidine nucleobase metabolic process Source: InterPro
  2. pyrimidine nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciCSP266779:GI09-3943-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylaseUniRule annotation (EC:2.4.2.4UniRule annotation)
Alternative name(s):
TdRPaseUniRule annotation
Gene namesi
Ordered Locus Names:Meso_3880
OrganismiChelativorans sp. (strain BNC1)
Taxonomic identifieri266779 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeChelativorans
ProteomesiUP000001820: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 509509Putative thymidine phosphorylasePRO_0000314702Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi266779.Meso_3880.

Structurei

3D structure databases

ProteinModelPortaliQ11BH8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000252767.
KOiK00758.
OMAiHAKVGYR.
OrthoDBiEOG61ZTGG.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPiMF_00703. Thymid_phosp_2.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000478. TP_PyNP. 1 hit.
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q11BH8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTALVSPAGP EQPSLRVRRL LLHTQHQPVV VMHTDCHVCR SEGLAARSQV
60 70 80 90 100
LLTNGARQVH ATLFQVDGDA VLSHDEVGLS ETAWDLLGVA EGDEVRVSHP
110 120 130 140 150
PALESLASVR RRIYGHRLDA QALSEIVRDV AAGRYTDVHL AAFLTASAAL
160 170 180 190 200
PLDENETADL TGAMIAVGDR MEWDAPTVVD KHCVGGLPGN RTTPIVVAIV
210 220 230 240 250
AANGLVMPKT SSRAITSPAG TADTMETLAP VDLDLATLRR VVEAEGGCIA
260 270 280 290 300
WGGAVHLSPA DDIFVRVERE LDVDTEGQLI ASVLSKKISA GSTHVVIDIP
310 320 330 340 350
VGPTAKVRGE DAASHLASRI TAVASRFGLA ATCVQTDGSQ PVGRGIGPAL
360 370 380 390 400
EAFDVLAVLQ NASDAPDDLR RRAATLAGAA LEIGRKAGKG EGTALALETL
410 420 430 440 450
ADGRAWKKFE AICEAQGGLR APPRAAHVHP LVAPRAGRVV HINNRKLSRL
460 470 480 490 500
AKLAGAPESK AGGVHMDVRL GDEIDRGQPL LHVHAETTGE LAYALDYAAR

AGDIVEIEA
Length:509
Mass (Da):53,390
Last modified:August 22, 2006 - v1
Checksum:i585D372C3D867E70
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000390 Genomic DNA. Translation: ABG65247.1.
RefSeqiWP_011583188.1. NC_008254.1.
YP_676412.1. NC_008254.1.

Genome annotation databases

EnsemblBacteriaiABG65247; ABG65247; Meso_3880.
GeneIDi4181668.
KEGGimes:Meso_3880.
PATRICi21348140. VBICheSp72577_4670.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000390 Genomic DNA. Translation: ABG65247.1.
RefSeqiWP_011583188.1. NC_008254.1.
YP_676412.1. NC_008254.1.

3D structure databases

ProteinModelPortaliQ11BH8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi266779.Meso_3880.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG65247; ABG65247; Meso_3880.
GeneIDi4181668.
KEGGimes:Meso_3880.
PATRICi21348140. VBICheSp72577_4670.

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000252767.
KOiK00758.
OMAiHAKVGYR.
OrthoDBiEOG61ZTGG.

Enzyme and pathway databases

BioCyciCSP266779:GI09-3943-MONOMER.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPiMF_00703. Thymid_phosp_2.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000478. TP_PyNP. 1 hit.
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BNC1.

Entry informationi

Entry nameiTYPH_CHESB
AccessioniPrimary (citable) accession number: Q11BH8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 22, 2006
Last modified: January 7, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.