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Q11BC3

- PNP_CHESB

UniProt

Q11BC3 - PNP_CHESB

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Protein
Polyribonucleotide nucleotidyltransferase
Gene
pnp, Meso_3935
Organism
Chelativorans sp. (strain BNC1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction By similarity.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi488 – 4881Magnesium By similarity
Metal bindingi494 – 4941Magnesium By similarity

GO - Molecular functioni

  1. 3'-5'-exoribonuclease activity Source: InterPro
  2. RNA binding Source: UniProtKB-HAMAP
  3. magnesium ion binding Source: UniProtKB-HAMAP
  4. polyribonucleotide nucleotidyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. RNA processing Source: InterPro
  2. mRNA catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

Magnesium, Metal-binding, RNA-binding

Enzyme and pathway databases

BioCyciCSP266779:GI09-4000-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferase (EC:2.7.7.8)
Alternative name(s):
Polynucleotide phosphorylase
Short name:
PNPase
Gene namesi
Name:pnp
Ordered Locus Names:Meso_3935
OrganismiChelativorans sp. (strain BNC1)
Taxonomic identifieri266779 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeChelativorans
ProteomesiUP000001820: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 715715Polyribonucleotide nucleotidyltransferaseUniRule annotation
PRO_0000329710Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi266779.Meso_3935.

Structurei

3D structure databases

ProteinModelPortaliQ11BC3.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini555 – 61460KH
Add
BLAST
Domaini624 – 69269S1 motif
Add
BLAST

Sequence similaritiesi

Contains 1 KH domain.
Contains 1 S1 motif domain.

Phylogenomic databases

eggNOGiCOG1185.
HOGENOMiHOG000218327.
KOiK00962.
OMAiPRWDWVA.
OrthoDBiEOG6WT8CC.

Family and domain databases

Gene3Di1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPiMF_01595. PNPase.
InterProiIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. RNA-binding_domain_S1.
[Graphical view]
PANTHERiPTHR11252. PTHR11252. 1 hit.
PfamiPF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
[Graphical view]
PIRSFiPIRSF005499. PNPase. 1 hit.
SMARTiSM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsiTIGR03591. polynuc_phos. 1 hit.
PROSITEiPS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q11BC3-1 [UniParc]FASTAAdd to Basket

« Hide

MFNHHKVEIE WGGRPLILET GKIARQADGA VLATYGETVV LATVVSAKEP    50
KPGIDFFPLT VNYQEKTFAA GKIPGGYFKR EGRPSEKETL VSRLIDRPIR 100
PLFVEGYKND TQVIITVLQH DLENDPDILS MVAASAALTL SGVPFMGPVG 150
AARVGYVGGE YILNPHLDEM AETKLDLVVA GTSDAVLMVE SEAHELPEDV 200
MLGAVMFGHR NFQPVIDAII KLAEVAAKEP REFLPEDLSA LEAEMLKVVE 250
ADLRDAYKIT NKQARYDAVN AAKAKVKEAF LPEGAEAYKW TPEQVATVFK 300
ALQAKIVRWN ILDTGSRIDG RDLRSVRPIV AEVGVLPRTH GSAVFTRGET 350
QALVVATLGT GEDEQYVDSL TGTVKETFML HYNFPPYSVG ETGRMGSPGR 400
REIGHGKLAW RAVHPLLPAP EQFPYTIRVV SEITESNGSS SMATVCGTSL 450
ALMDAGVPLA KPVAGIAMGL IKEDDRFAVL SDILGDEDHL GDMDFKVAGT 500
AEGVTSLQMD IKITGITEEI MKVALEQAKD GRLHILGEMA NALSESRGEL 550
GEFAPRIEVM HIPTDKIRDV IGTGGKVIRE IVEKTGAKIN IEDDGTVKIA 600
SSNGKEIEAA RKWIHSIVAE PEVGEIYEGT VVKTADFGAF VNFFGPRDGL 650
VHISQLAPER VQKTTDVVKE GDKVFVKLMG FDERGKVRLS MKVVDQETGK 700
EIVQEKKEEK QEAEG 715
Length:715
Mass (Da):77,890
Last modified:August 22, 2006 - v1
Checksum:i10D51FC956F2CB0E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000390 Genomic DNA. Translation: ABG65302.1.
RefSeqiWP_011583243.1. NC_008254.1.
YP_676467.1. NC_008254.1.

Genome annotation databases

EnsemblBacteriaiABG65302; ABG65302; Meso_3935.
GeneIDi4180416.
KEGGimes:Meso_3935.
PATRICi21348260. VBICheSp72577_4728.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000390 Genomic DNA. Translation: ABG65302.1 .
RefSeqi WP_011583243.1. NC_008254.1.
YP_676467.1. NC_008254.1.

3D structure databases

ProteinModelPortali Q11BC3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 266779.Meso_3935.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG65302 ; ABG65302 ; Meso_3935 .
GeneIDi 4180416.
KEGGi mes:Meso_3935.
PATRICi 21348260. VBICheSp72577_4728.

Phylogenomic databases

eggNOGi COG1185.
HOGENOMi HOG000218327.
KOi K00962.
OMAi PRWDWVA.
OrthoDBi EOG6WT8CC.

Enzyme and pathway databases

BioCyci CSP266779:GI09-4000-MONOMER.

Family and domain databases

Gene3Di 1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPi MF_01595. PNPase.
InterProi IPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. RNA-binding_domain_S1.
[Graphical view ]
PANTHERi PTHR11252. PTHR11252. 1 hit.
Pfami PF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
[Graphical view ]
PIRSFi PIRSF005499. PNPase. 1 hit.
SMARTi SM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsi TIGR03591. polynuc_phos. 1 hit.
PROSITEi PS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BNC1.

Entry informationi

Entry nameiPNP_CHESB
AccessioniPrimary (citable) accession number: Q11BC3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: August 22, 2006
Last modified: September 3, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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