Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q119Z5

- SYE_TRIEI

UniProt

Q119Z5 - SYE_TRIEI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamate--tRNA ligase

Gene

gltX

Organism
Trichodesmium erythraeum (strain IMS101)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).By similarity

Catalytic activityi

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei251 – 2511ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutamate-tRNA ligase activity Source: UniProtKB-EC
  3. tRNA binding Source: InterPro

GO - Biological processi

  1. glutamyl-tRNA aminoacylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTERY203124:GJDR-190-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate--tRNA ligase (EC:6.1.1.17)
Alternative name(s):
Glutamyl-tRNA synthetase
Short name:
GluRS
Gene namesi
Name:gltX
Ordered Locus Names:Tery_0188
OrganismiTrichodesmium erythraeum (strain IMS101)
Taxonomic identifieri203124 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeOscillatorialesTrichodesmium
ProteomesiUP000008878: Chromosome

Subcellular locationi

Cytoplasm By similarity. Cell membrane Curated; Multi-pass membrane protein Curated

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei809 – 82921HelicalSequence AnalysisAdd
BLAST
Transmembranei832 – 85221HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
  2. integral component of membrane Source: UniProtKB-KW
  3. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 881881Glutamate--tRNA ligasePRO_0000367797Add
BLAST

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi203124.Tery_0188.

Structurei

3D structure databases

ProteinModelPortaliQ119Z5.
SMRiQ119Z5. Positions 2-480.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 480480Glutamyl-tRNA synthetaseAdd
BLAST
Regioni481 – 881401UnknownAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi9 – 1911"HIGH" regionAdd
BLAST
Motifi248 – 2525"KMSKS" region

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi510 – 772263Thr-richAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0008.
KOiK01885.
OrthoDBiEOG6DRPF7.

Family and domain databases

Gene3Di1.10.10.350. 1 hit.
1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00022_B. Glu_tRNA_synth_B.
InterProiIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR025564. CAAD_dom.
IPR004527. Glu-tRNA-ligase_bac/mito.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF14159. CAAD. 1 hit.
PF00749. tRNA-synt_1c. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF48163. SSF48163. 1 hit.
TIGRFAMsiTIGR00464. gltX_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q119Z5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSVRVRLAPS PTGNLHIGTA RTAVFNWLFA RNQKGKFILR IEDTDQERSR
60 70 80 90 100
PEYTDNILEG LSWLGLEWDE GPFYQCQRYE LYQKATQSLL DKGLAYRCYC
110 120 130 140 150
TAAELEEMRE AQKARKEAPR YDNRHRNLTD LEKKAFEAEG RQAVIRFRID
160 170 180 190 200
DDQIITWNDM VRGKVTWKGS DLGGDMVISR AAGGDEVGQP LYNMAVVVDD
210 220 230 240 250
MDMEITHVIR GEDHIANTAK QILLYEALGG KIPEFGHTPL ILNKEGRKLS
260 270 280 290 300
KRDGVTSISD FQELGFTPEA LANYMCLLGW TPPDATEEIF TLAQAGQNFS
310 320 330 340 350
FERVNKAGAK FDWDKLDWIS SQYLHNLPVK QLTDKLIPIW QKAGYELDPE
360 370 380 390 400
GDRSWLEQLV TLIRPSLTRL TDAVEMSELF FFPTVELNED AKTQMQNEDS
410 420 430 440 450
VKSINSILEI INADAPLLVA DVKQTIKKVT QKVHVKKGVV MRSLRASLTG
460 470 480 490 500
AMQGPDLIES WLLLHQKGFD ILRFKKSIGQ EIEDTKIEDT KKAETTPHKS
510 520 530 540 550
KGEGNVLLKT TTPKSPALSK EQTQTTKPPK KGQTATPVAT TPTATDVTEN
560 570 580 590 600
TSVGTQETQS QITTPVATTP TATDVTENTS VGTQETQSQI TTPVATTPTA
610 620 630 640 650
TDVTENTSVE TQETQSQITT PVATTPTATD VTENTSVETQ ETQSQITTPV
660 670 680 690 700
ATTPTATDVT ENTSVGTQET QSQITTPVAT TPTATDVTEN TSVETQETQS
710 720 730 740 750
QITTPVATTS TATDVTENTS VETQETQSQI TTPVATTPTA TDAETREQKV
760 770 780 790 800
ATQVETSILD DQKPVDTVTN QTVEVEQPNK IKEQFINIFF NFPDYINQLY
810 820 830 840 850
QQYQGQLKLF GWLALVILTF TFMAVVIEAL DGIPILSIIF ELIGVIYLVW
860 870 880
FVYRYLLKRS NRQELLDKIE NIKREIFGKP S
Length:881
Mass (Da):98,269
Last modified:August 22, 2006 - v1
Checksum:i1C675432E0CA07E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000393 Genomic DNA. Translation: ABG49679.1.
RefSeqiWP_011610076.1. NC_008312.1.
YP_720152.1. NC_008312.1.

Genome annotation databases

EnsemblBacteriaiABG49679; ABG49679; Tery_0188.
GeneIDi4242194.
KEGGiter:Tery_0188.
PATRICi23983588. VBITriEry99848_0240.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000393 Genomic DNA. Translation: ABG49679.1 .
RefSeqi WP_011610076.1. NC_008312.1.
YP_720152.1. NC_008312.1.

3D structure databases

ProteinModelPortali Q119Z5.
SMRi Q119Z5. Positions 2-480.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 203124.Tery_0188.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG49679 ; ABG49679 ; Tery_0188 .
GeneIDi 4242194.
KEGGi ter:Tery_0188.
PATRICi 23983588. VBITriEry99848_0240.

Phylogenomic databases

eggNOGi COG0008.
KOi K01885.
OrthoDBi EOG6DRPF7.

Enzyme and pathway databases

BioCyci TERY203124:GJDR-190-MONOMER.

Family and domain databases

Gene3Di 1.10.10.350. 1 hit.
1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPi MF_00022_B. Glu_tRNA_synth_B.
InterProi IPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR025564. CAAD_dom.
IPR004527. Glu-tRNA-ligase_bac/mito.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR10119. PTHR10119. 1 hit.
Pfami PF14159. CAAD. 1 hit.
PF00749. tRNA-synt_1c. 1 hit.
[Graphical view ]
PRINTSi PR00987. TRNASYNTHGLU.
SUPFAMi SSF48163. SSF48163. 1 hit.
TIGRFAMsi TIGR00464. gltX_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IMS101.

Entry informationi

Entry nameiSYE_TRIEI
AccessioniPrimary (citable) accession number: Q119Z5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: August 22, 2006
Last modified: October 29, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3