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Q119Z5

- SYE_TRIEI

UniProt

Q119Z5 - SYE_TRIEI

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Protein
Glutamate--tRNA ligase
Gene
gltX, Tery_0188
Organism
Trichodesmium erythraeum (strain IMS101)
Status
Reviewed - Annotation score: 4 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) By similarity.UniRule annotation

Catalytic activityi

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei251 – 2511ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutamate-tRNA ligase activity Source: UniProtKB-EC
  3. tRNA binding Source: InterPro

GO - Biological processi

  1. glutamyl-tRNA aminoacylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTERY203124:GJDR-190-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate--tRNA ligase (EC:6.1.1.17)
Alternative name(s):
Glutamyl-tRNA synthetase
Short name:
GluRS
Gene namesi
Name:gltX
Ordered Locus Names:Tery_0188
OrganismiTrichodesmium erythraeum (strain IMS101)
Taxonomic identifieri203124 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeOscillatorialesTrichodesmium
ProteomesiUP000008878: Chromosome

Subcellular locationi

Cytoplasm By similarity. Cell membrane; Multi-pass membrane protein Reviewed prediction UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei809 – 82921Helical; Reviewed prediction
Add
BLAST
Transmembranei832 – 85221Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. integral component of membrane Source: UniProtKB-KW
  3. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 881881Glutamate--tRNA ligaseUniRule annotation
PRO_0000367797Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi203124.Tery_0188.

Structurei

3D structure databases

ProteinModelPortaliQ119Z5.
SMRiQ119Z5. Positions 2-480.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 480480Glutamyl-tRNA synthetaseUniRule annotation
Add
BLAST
Regioni481 – 881401UnknownUniRule annotation
Add
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi9 – 1911"HIGH" regionUniRule annotation
Add
BLAST
Motifi248 – 2525"KMSKS" regionUniRule annotation

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi510 – 772263Thr-richUniRule annotation
Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0008.
KOiK01885.
OrthoDBiEOG6DRPF7.

Family and domain databases

Gene3Di1.10.10.350. 1 hit.
1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00022_B. Glu_tRNA_synth_B.
InterProiIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR025564. CAAD_dom.
IPR004527. Glu-tRNA-ligase_bac/mito.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF14159. CAAD. 1 hit.
PF00749. tRNA-synt_1c. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF48163. SSF48163. 1 hit.
TIGRFAMsiTIGR00464. gltX_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q119Z5-1 [UniParc]FASTAAdd to Basket

« Hide

MSVRVRLAPS PTGNLHIGTA RTAVFNWLFA RNQKGKFILR IEDTDQERSR    50
PEYTDNILEG LSWLGLEWDE GPFYQCQRYE LYQKATQSLL DKGLAYRCYC 100
TAAELEEMRE AQKARKEAPR YDNRHRNLTD LEKKAFEAEG RQAVIRFRID 150
DDQIITWNDM VRGKVTWKGS DLGGDMVISR AAGGDEVGQP LYNMAVVVDD 200
MDMEITHVIR GEDHIANTAK QILLYEALGG KIPEFGHTPL ILNKEGRKLS 250
KRDGVTSISD FQELGFTPEA LANYMCLLGW TPPDATEEIF TLAQAGQNFS 300
FERVNKAGAK FDWDKLDWIS SQYLHNLPVK QLTDKLIPIW QKAGYELDPE 350
GDRSWLEQLV TLIRPSLTRL TDAVEMSELF FFPTVELNED AKTQMQNEDS 400
VKSINSILEI INADAPLLVA DVKQTIKKVT QKVHVKKGVV MRSLRASLTG 450
AMQGPDLIES WLLLHQKGFD ILRFKKSIGQ EIEDTKIEDT KKAETTPHKS 500
KGEGNVLLKT TTPKSPALSK EQTQTTKPPK KGQTATPVAT TPTATDVTEN 550
TSVGTQETQS QITTPVATTP TATDVTENTS VGTQETQSQI TTPVATTPTA 600
TDVTENTSVE TQETQSQITT PVATTPTATD VTENTSVETQ ETQSQITTPV 650
ATTPTATDVT ENTSVGTQET QSQITTPVAT TPTATDVTEN TSVETQETQS 700
QITTPVATTS TATDVTENTS VETQETQSQI TTPVATTPTA TDAETREQKV 750
ATQVETSILD DQKPVDTVTN QTVEVEQPNK IKEQFINIFF NFPDYINQLY 800
QQYQGQLKLF GWLALVILTF TFMAVVIEAL DGIPILSIIF ELIGVIYLVW 850
FVYRYLLKRS NRQELLDKIE NIKREIFGKP S 881
Length:881
Mass (Da):98,269
Last modified:August 22, 2006 - v1
Checksum:i1C675432E0CA07E9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000393 Genomic DNA. Translation: ABG49679.1.
RefSeqiYP_720152.1. NC_008312.1.

Genome annotation databases

EnsemblBacteriaiABG49679; ABG49679; Tery_0188.
GeneIDi4242194.
KEGGiter:Tery_0188.
PATRICi23983588. VBITriEry99848_0240.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000393 Genomic DNA. Translation: ABG49679.1 .
RefSeqi YP_720152.1. NC_008312.1.

3D structure databases

ProteinModelPortali Q119Z5.
SMRi Q119Z5. Positions 2-480.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 203124.Tery_0188.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG49679 ; ABG49679 ; Tery_0188 .
GeneIDi 4242194.
KEGGi ter:Tery_0188.
PATRICi 23983588. VBITriEry99848_0240.

Phylogenomic databases

eggNOGi COG0008.
KOi K01885.
OrthoDBi EOG6DRPF7.

Enzyme and pathway databases

BioCyci TERY203124:GJDR-190-MONOMER.

Family and domain databases

Gene3Di 1.10.10.350. 1 hit.
1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPi MF_00022_B. Glu_tRNA_synth_B.
InterProi IPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR025564. CAAD_dom.
IPR004527. Glu-tRNA-ligase_bac/mito.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR10119. PTHR10119. 1 hit.
Pfami PF14159. CAAD. 1 hit.
PF00749. tRNA-synt_1c. 1 hit.
[Graphical view ]
PRINTSi PR00987. TRNASYNTHGLU.
SUPFAMi SSF48163. SSF48163. 1 hit.
TIGRFAMsi TIGR00464. gltX_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IMS101.

Entry informationi

Entry nameiSYE_TRIEI
AccessioniPrimary (citable) accession number: Q119Z5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: August 22, 2006
Last modified: February 19, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3