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Protein

Histidine kinase

Gene

Tery_0661

Organism
Trichodesmium erythraeum (strain IMS101)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.SAAS annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphorelay sensor kinase activity Source: InterPro
  3. phosphorus-oxygen lyase activity Source: InterPro

GO - Biological processi

  1. cyclic nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotation, Transferase

Keywords - Biological processi

Two-component regulatory systemSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciTERY203124:GJDR-667-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Histidine kinaseSAAS annotation (EC:2.7.13.3SAAS annotation)
Gene namesi
Ordered Locus Names:Tery_0661Imported
OrganismiTrichodesmium erythraeum (strain IMS101)Imported
Taxonomic identifieri203124 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeOscillatorialesTrichodesmium
ProteomesiUP000008878: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

PhosphoproteinSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi203124.Tery_0661.

Structurei

3D structure databases

ProteinModelPortaliQ118H4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains histidine kinase domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0642.
HOGENOMiHOG000120898.
OMAiITHTHEM.
OrthoDBiEOG6G4VQG.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR004010. Cache_domain.
IPR011006. CheY-like_superfamily.
IPR003661. EnvZ-like_dim/P.
IPR003660. HAMP_linker_domain.
IPR003594. HATPase_C.
IPR029787. Nucleotide_cyclase.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF02743. Cache_1. 1 hit.
PF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00044. CYCc. 1 hit.
SM00304. HAMP. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF52172. SSF52172. 1 hit.
SSF55073. SSF55073. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
PS50109. HIS_KIN. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q118H4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFKSLSLNL GRIFSKLSLK TILIVPYVIQ ILGAFGALGY IAFLNGQQTV
60 70 80 90 100
DDLGKKLTNK ISDRIQQHVL GYLNQSHQVL RITNDAIESA NLDIYNFVAL
110 120 130 140 150
RRYFWEVVKE KDLQDYLFFG NEEGEFIGVE HFAEGEIYLK SCKIPTQSLC
160 170 180 190 200
ETYLLNNQGN ISQYLNSKEY DPRDTPWYLV AKKLGEPTWS PILSSFSGQN
210 220 230 240 250
SSLDIFAVQP IFDSTENLLG VLSNKTTLVK LTNFLKNLYI SPNGQSFIIE
260 270 280 290 300
RSGNLIASSE VMEPFVIKGT QENRKIERLP ATASENKIVS MTTKHLQQKF
310 320 330 340 350
SSFAEITHTH EMNFPIEEEW YYASVIPVID GRGINWLAVV VIPEDDFMEK
360 370 380 390 400
VNMNIRTTIL LSFAALTITV LLGIVTTNWI TKPILQLNSA AKEISQGKWE
410 420 430 440 450
TQLKIYREDE LGELANSFDQ MASQLKKSFE TLEAQNKQLT ELDRLKDEFL
460 470 480 490 500
ANTSHELRTP LNGIIGIGEF LLEENTKNLN SITTSNLAII VSSARRLSNL
510 520 530 540 550
VNDILDFSKI RYHKLELQVR AIDVRIVVES VITLNRVLVG KNKNLQLTNA
560 570 580 590 600
IPTDLPPVLA DENRLQQILY NLIANAIKFT ESGKVEISAS LYSPKEDQDE
610 620 630 640 650
ATEIIIMVSD TGIGIPPDQL DRIFESFEQG EGSIIRKYGG TGLGLAVTKE
660 670 680 690 700
LVELQGGRIW VESEVGVGSR FNVTLPISNQ LVPNSSLNFP SPTVNNIHYL
710 720 730 740 750
IKNIETTIRS KPLGSKIPNG DFHVLVVDDE PINIQVLNNY LKANNYQVTQ
760 770 780 790 800
ALSGKEALAA LENNHNFDLI LLDVMMPNMS GYEVCSQIRE KYPAQSLPVL
810 820 830 840 850
MLTAKNQIAD LVMGFQFGAN DYLTKPFAKD ELLTRIQTHI KLSKITKAYE
860 870 880 890 900
RFVPHEYVEL LSKESIINVK LGDRVSTKMA IFFSDIRSFT TISEQMTSQE
910 920 930 940 950
TFAFVNGYLK EVCPEIRDRN GLIIKFLGDG IMAVFPDGAD DALEAAIAQL
960 970 980 990 1000
KRLQEYNQVL LSTGWMPIKI GIGIHWGHIM VGIVGEKGRM SGDAFSNNVN
1010 1020 1030 1040 1050
LTSRLEGLTK FYGVSLLISE SAFNYLKNPQ KYQIRFLDRA SVKGIDEPIN
1060 1070 1080 1090 1100
VYEVLDGEVD EIRELKLQTQ VDFALGLESY RVGELVDAKD YFEKVLAVNY
1110 1120 1130
SDKTAQLYLE RIDDLMVTGV PKNWNGVWAF TQK
Length:1,133
Mass (Da):127,530
Last modified:August 22, 2006 - v1
Checksum:iCEE3F83838FF0FD5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000393 Genomic DNA. Translation: ABG50100.1.
RefSeqiYP_720573.1. NC_008312.1.

Genome annotation databases

EnsemblBacteriaiABG50100; ABG50100; Tery_0661.
GeneIDi4243168.
KEGGiter:Tery_0661.
PATRICi23984769. VBITriEry99848_0825.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000393 Genomic DNA. Translation: ABG50100.1.
RefSeqiYP_720573.1. NC_008312.1.

3D structure databases

ProteinModelPortaliQ118H4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi203124.Tery_0661.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG50100; ABG50100; Tery_0661.
GeneIDi4243168.
KEGGiter:Tery_0661.
PATRICi23984769. VBITriEry99848_0825.

Phylogenomic databases

eggNOGiCOG0642.
HOGENOMiHOG000120898.
OMAiITHTHEM.
OrthoDBiEOG6G4VQG.

Enzyme and pathway databases

BioCyciTERY203124:GJDR-667-MONOMER.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR004010. Cache_domain.
IPR011006. CheY-like_superfamily.
IPR003661. EnvZ-like_dim/P.
IPR003660. HAMP_linker_domain.
IPR003594. HATPase_C.
IPR029787. Nucleotide_cyclase.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF02743. Cache_1. 1 hit.
PF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00044. CYCc. 1 hit.
SM00304. HAMP. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF52172. SSF52172. 1 hit.
SSF55073. SSF55073. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
PS50109. HIS_KIN. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IMS101Imported.

Entry informationi

Entry nameiQ118H4_TRIEI
AccessioniPrimary (citable) accession number: Q118H4
Entry historyi
Integrated into UniProtKB/TrEMBL: August 22, 2006
Last sequence update: August 22, 2006
Last modified: March 4, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.