tal

Functionⁱ

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityⁱ

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotation

Pathwayⁱ: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:

no protein annotated in this organism
Transaldolase (Tery_0519), Transaldolase (tal), Transaldolase (tal)
no protein annotated in this organism

This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Active siteⁱ	141	Schiff-base intermediate with substrateUniRule annotation		1

GO - Molecular functionⁱ

sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Source: UniProtKB-EC

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

carbohydrate metabolic process Source: InterPro
pentose-phosphate shunt Source: UniProtKB-UniPathway

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Transferase
Biological process	Pentose shunt
Ligand	Schiff base

Enzyme and pathway databases

BioCycⁱ	TERY203124:G1G6S-700-MONOMER
UniPathwayⁱ	UPA00115; UER00414

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: TransaldolaseUniRule annotation (EC:2.2.1.2UniRule annotation)
Gene namesⁱ	Name:talUniRule annotation Ordered Locus Names:Tery_0683
Organismⁱ	Trichodesmium erythraeum (strain IMS101)
Taxonomic identifierⁱ	203124 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Terrabacteria group › Cyanobacteria › Oscillatoriophycideae › Oscillatoriales › Microcoleaceae › Trichodesmium › Trichodesmium erythraeum
Proteomesⁱ	UP000008878 Componentⁱ: Chromosome

Subcellular locationⁱ

Cytoplasm
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_00493

GO - Cellular componentⁱ

cytoplasm Source: UniProtKB-SubCell

View the complete GO annotation on QuickGO ...

Keywords - Cellular componentⁱ

Cytoplasm

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_1000026533	1 – 380	TransaldolaseAdd BLAST		380

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	203124.Tery_0683

STRINGⁱ

203124.Tery_0683

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q118F4
SMRⁱ	Q118F4
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the transaldolase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGⁱ	ENOG4107QQX Bacteria COG0176 LUCA
HOGENOMⁱ	HOG000226074
KEGG Orthology (KO) More...KOⁱ	K00616
OMAⁱ	ATECYYQ
Database of Orthologous Groups More...OrthoDBⁱ	POG091H05PS

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00955 Transaldolase_like, 1 hit
Gene3Dⁱ	3.20.20.701 hit
HAMAPⁱ	MF_00493 Transaldolase_2, 1 hit
InterProⁱ	View protein in InterPro IPR013785 Aldolase_TIM IPR001585 TAL/FSA IPR004732 Transaldolase_2 IPR018225 Transaldolase_AS
PANTHERⁱ	PTHR10683 PTHR10683, 1 hit PTHR10683:SF19 PTHR10683:SF19, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00923 TAL_FSA, 1 hit
PIRSFⁱ	PIRSF036915 Trnald_Bac_Plnt, 1 hit
TIGRFAMsⁱ	TIGR00876 tal_mycobact, 1 hit
PROSITEⁱ	View protein in PROSITE PS01054 TRANSALDOLASE_1, 1 hit PS00958 TRANSALDOLASE_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q118F4-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MVTNHLLEIE NLGQSIWMDN LSRNIIESGE LKSMIGKKGI RGITSNPAIF 
        60         70         80         90        100
EKAIAGNAIY DADIEAGIKA SKSVIEIYES LVFKDIRDAC DIFMPVYEET 
       110        120        130        140        150
KGLDGYISIE VPPTIAKDTE STISEAIRYY TAIGRENLMI KIPGTPEGLP 
       160        170        180        190        200
AVTRVISEGI NVNVTLLFSV ESYINTAWAY IEGLEARAAK GEDIDKIASV 
       210        220        230        240        250
ASFFLSRIDS NIDGLIDEKL KKVTDETVKA KLEAVKGKVA IANAKIAYQE 
       260        270        280        290        300
YKKIIQSDRW KALSAKGAKE QRLLWASTST KNPAYSDVMY VDELIGPNTV 
       310        320        330        340        350
NTLPPPTIDA CADHCDVDNR VETNIEVTKE VMENLKDPDI NINIDQVMEQ 
       360        370        380
LLVEGIDKFI KPFTSLINSL EEKVKKLTPV

Length:380

Mass (Da):42,023

Last modified:August 22, 2006 - v1

Checksum:ⁱAC0C4ED2B9F16FE1

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000393 Genomic DNA Translation: ABG50120.1
NCBI Reference Sequences More...RefSeqⁱ	WP_011610513.1, NC_008312.1

Genome annotation databases

EnsemblBacteriaⁱ	ABG50120; ABG50120; Tery_0683
KEGGⁱ	ter:Tery_0683

Similar proteinsⁱ

50% Identity

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q118F4	P48983 A0A235IHD3 A0A2L2NRU0 A0A2K8SSM2 A0A2L2NDP6 A0A235IEH3 A0A235IQ44 A0A2D0HF84 A0A1E2WS16 UPI000D0699F0 +203	Nostoc punctiforme (strain ATCC 29133 / PCC 73102) Nostoc sp. 'Peltigera membranacea cyanobiont' 210A Nostoc sp. 'Lobaria pulmonaria (5183) cyanobiont' Nostoc flagelliforme CCNUN1 Nostoc sp. 'Peltigera membranacea cyanobiont N6' Nostoc sp. 'Peltigera membranacea cyanobiont' 213 Nostoc sp. 'Peltigera membranacea cyanobiont' 232 Nostoc sp. 'Peltigera malacea cyanobiont' DB3992 Nostoc sp. KVJ20 Pleurocapsa sp. CCALA 161 And more	381	UniRef50_P48983	Cluster: Transaldolase 2	214

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000393 Genomic DNA Translation: ABG50120.1
NCBI Reference Sequences More...RefSeqⁱ	WP_011610513.1, NC_008312.1

3D structure databases

ProteinModelPortalⁱ	Q118F4
SMRⁱ	Q118F4
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	203124.Tery_0683

STRINGⁱ

203124.Tery_0683

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	ABG50120; ABG50120; Tery_0683
KEGGⁱ	ter:Tery_0683

Phylogenomic databases

eggNOGⁱ	ENOG4107QQX Bacteria COG0176 LUCA
HOGENOMⁱ	HOG000226074
KEGG Orthology (KO) More...KOⁱ	K00616
OMAⁱ	ATECYYQ
Database of Orthologous Groups More...OrthoDBⁱ	POG091H05PS

Enzyme and pathway databases

UniPathwayⁱ	UPA00115; UER00414
BioCycⁱ	TERY203124:G1G6S-700-MONOMER

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00955 Transaldolase_like, 1 hit
Gene3Dⁱ	3.20.20.701 hit
HAMAPⁱ	MF_00493 Transaldolase_2, 1 hit
InterProⁱ	View protein in InterPro IPR013785 Aldolase_TIM IPR001585 TAL/FSA IPR004732 Transaldolase_2 IPR018225 Transaldolase_AS
PANTHERⁱ	PTHR10683 PTHR10683, 1 hit PTHR10683:SF19 PTHR10683:SF19, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00923 TAL_FSA, 1 hit
PIRSFⁱ	PIRSF036915 Trnald_Bac_Plnt, 1 hit
TIGRFAMsⁱ	TIGR00876 tal_mycobact, 1 hit
PROSITEⁱ	View protein in PROSITE PS01054 TRANSALDOLASE_1, 1 hit PS00958 TRANSALDOLASE_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	TAL_TRIEI
Accessionⁱ	Q118F4Primary (citable) accession number: Q118F4
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
	Last sequence update:	August 22, 2006
	Last modified:	February 28, 2018
	This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q118F4 (TAL_TRIEI)

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Transaldolase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">‘Function’</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: pentose phosphate pathway

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

Pathwayⁱ: pentose phosphate pathway

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ