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Protein

Methionyl-tRNA formyltransferase

Gene

fmt

Organism
Trichodesmium erythraeum (strain IMS101)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.UniRule annotation

Catalytic activityi

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionTransferase
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Methionyl-tRNA formyltransferaseUniRule annotation (EC:2.1.2.9UniRule annotation)
Gene namesi
Name:fmtUniRule annotation
Ordered Locus Names:Tery_1769
OrganismiTrichodesmium erythraeum (strain IMS101)
Taxonomic identifieri203124 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeOscillatorialesMicrocoleaceaeTrichodesmium
Proteomesi
  • UP000008878 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000202001 – 336Methionyl-tRNA formyltransferaseAdd BLAST336

Interactioni

Protein-protein interaction databases

STRINGi203124.Tery_1769

Structurei

3D structure databases

ProteinModelPortaliQ114P5
SMRiQ114P5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni112 – 115Tetrahydrofolate (THF) bindingUniRule annotation4

Sequence similaritiesi

Belongs to the Fmt family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CAE Bacteria
COG0223 LUCA
HOGENOMiHOG000261177
KOiK00604
OMAiLRIVFMG
OrthoDBiPOG091H01YM

Family and domain databases

Gene3Di3.10.25.10, 1 hit
HAMAPiMF_00182 Formyl_trans, 1 hit
InterProiView protein in InterPro
IPR005794 Fmt
IPR005793 Formyl_trans_C
IPR037022 Formyl_trans_C_sf
IPR002376 Formyl_transf_N
IPR036477 Formyl_transf_N_sf
IPR011034 Formyl_transferase-like_C_sf
IPR001555 GART_AS
PfamiView protein in Pfam
PF02911 Formyl_trans_C, 1 hit
PF00551 Formyl_trans_N, 1 hit
SUPFAMiSSF50486 SSF50486, 1 hit
SSF53328 SSF53328, 1 hit
TIGRFAMsiTIGR00460 fmt, 1 hit
PROSITEiView protein in PROSITE
PS00373 GART, 1 hit

Sequencei

Sequence statusi: Complete.

Q114P5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMKIIFFGTP LFAVPTLKKL LDNPKIEVTA VVTQPDKRRG RGNKLIPSPV
60 70 80 90 100
KSVAVAHNIP VWQPRRVKKN PETLNLLREA QADVFVVVAY GQILSTEILE
110 120 130 140 150
MPKLGCVNVH GSILPKYRGA APIQWSIYHG EAETGNTTML MDVGMDTGPM
160 170 180 190 200
LLKSIIPIGL LDNAVSIAEI LAKDGADLLL ETLLRLEDKE IEPIPQDNSL
210 220 230 240 250
ATYAPLIQNS DYEIDWSRSA LDIHNQIRGF FPNCFTSFRG QSLKVMATIP
260 270 280 290 300
VGTEYWSELP PELQKLEKVW SSESEVVGNI GEVVKVIKGL GPVVQTGSGW
310 320 330
LLLWQVQLAG KKVVSGWDFA NGTRLLVGEV SEVFSR
Length:336
Mass (Da):37,076
Last modified:August 22, 2006 - v1
Checksum:iE5CAFA7CF39AACFF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000393 Genomic DNA Translation: ABG51029.1

Genome annotation databases

EnsemblBacteriaiABG51029; ABG51029; Tery_1769
KEGGiter:Tery_1769

Similar proteinsi

Entry informationi

Entry nameiFMT_TRIEI
AccessioniPrimary (citable) accession number: Q114P5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 22, 2006
Last modified: March 28, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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